Biology Faculty Proceedings, Presentations, Speeches, Lectures
Modeling and Simulation of Caenorhabditis elegans Chemotaxis in Response to a Dynamic Engineered Bacteria
Event Name/Location
Human Anatomy and Physiology Society Southern Regional Conference, Fort Lauderdale, Florida, October 22, 2016
Presntation Date
10-22-2016
Document Type
Conference Proceeding
ORCID ID
0000-0002-4900-3099
Description
Nematodes remain important causative agents of diseases. While several studies have examined how nematodes behave in response to a chemoattractant, how the characteristics of the chemoattractant affect chemotaxis has yet to be explored. A mathematical model was created to examine how characteristics of chemoattractants affect chemotaxis in Caenorhabditis elegans. Specifically, toxic bacteria were engineered to express a chemoattractant. Under static conditions, the chemoattractant’s diffusion rate was proportional to attraction. If the nematodes learn that the chemoattractant is associated with toxicity, attraction is counterintuitively reduced with increasing diffusion rate. Results may have implications in novel treatments of parasitic infections.
NSUWorks Citation
Pandya, Divya A.; Haskell, Evan; Smith, Robert; and Blanar, Christopher A., "Modeling and Simulation of Caenorhabditis elegans Chemotaxis in Response to a Dynamic Engineered Bacteria" (2016). Biology Faculty Proceedings, Presentations, Speeches, Lectures. 379.
https://nsuworks.nova.edu/cnso_bio_facpres/379
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