Title

Forensic DNA Analysis

Authors

Bruce R. McCord, Florida International University
Quentin Gauthier, Florida International University
Sohee Cho, Seoul National University - South Korea
Meghan N. Roig, Florida International University
Georgiana C. Gibson-Daw, Florida International University
Brian Young, Niche Vision, Inc.
Fabiana Taglia, Florida International University
Sara C. Zapico, Florida International University
Roberta Fogliatto Mariot, Florida International University
Steven B. Lee, San Jose State University
George Duncan, Florida International UniversityFollow

Document Type

Article

Publication Date

11-28-2018

Publication Title

Analytical Chemistry

ISSN

1520-6882

First Page

1

Last Page

52

Abstract

This review focuses on recent developments in forensic DNA typing. It highlights important recent advances and issues in forensic human identification and identifies representative papers. It is not intended to be comprehensive. The review is divided into several important topic areas. These include developments in forensic serology using RNA, proteomic, and Epigenetic markers, and methods for human identification using short tandem repeats, single nucleotide polymorphisms, and insertion deletions. Sequencing methods for autosomal DNA, sex linked DNA, and mitochondrial DNA are included as well as for the human microbiome. New technologies are also featured, such as real time PCR, microfluidics, integrated rapid PCR systems, and massively parallel sequencing. Expert systems have also been developed to assist with the analysis of data from these complex analytical tools.

Comments

©2018 American Chemical Society

NSUWorks Citation

McCord, Bruce R.; Quentin Gauthier; Sohee Cho; Meghan N. Roig; Georgiana C. Gibson-Daw; Brian Young; Fabiana Taglia; Sara C. Zapico; Roberta Fogliatto Mariot; Steven B. Lee; and George Duncan. 2018. "Forensic DNA Analysis." Analytical Chemistry , (): 1-52. doi:10.1021/acs.analchem.8b05318.

ORCID ID

0000-0002-4931-5316

DOI

10.1021/acs.analchem.8b05318