Biology Faculty Articles
Title
Human Phylogenetic Relationships According to the D1S80 Locus
Document Type
Article
Publication Date
1-1996
Publication Title
Genetica
Keywords
Amplified fragment length polymorphism, Forensic PCR analysis, Subpopulation structure
ISSN
0016-6707
Volume
98
Issue/No.
3
First Page
277
Last Page
287
Abstract
By analyzing the allelic frequencies at the D1S80 locus in 43 human populations, we show that the locus is polymorphic globally and that it can be used to discriminate between major racial groups and subpopulations through phylogenetic analysis. Although the use of informative multiple loci generally provides more accurate phylogenetic relationships, in instances where time and/or target DNA availability is limited, D1S80 could provide useful data to discriminate between human groups. Also, knowledge of which loci independently provide accurate phylogenetic relationships, such as the D1S80, can be used to design more accurate multi-locus combinations. In addition, allele frequencies at the locus are reported, for the first time, for Bahamian individuals of African origin and for Chimila, Bari, and Navajo (Cañoncito Valley) native Americans. Allelic data was obtained using standard polymerase chain reaction (PCR) techniques. In the four new populations, 65 genotypes and 20 segregating alleles were observed. All populations conformed to Hardy-Weinberg expectations except the Chimila.
NSUWorks Citation
Duncan, George; Emmanuel Thomas; Juan C. Gallol; Lynn S. Baird; Jennifer Garrison; and Rene J. Herrera. 1996. "Human Phylogenetic Relationships According to the D1S80 Locus." Genetica 98, (3): 277-287. doi:10.1007/BF00057592.
ORCID ID
0000-0002-4931-5316
DOI
10.1007/BF00057592
Comments
©1996 Kluwer Academic Publishers