Biology Faculty Articles
Document Type
Article
Publication Date
3-7-2014
Publication Title
Journal of Acquired Immune Deficiency Syndromes
ISSN
1525-4135
Volume
65
Issue/No.
Supplement 2
First Page
59
Last Page
59
Abstract
As genome wide association studies plus whole genome sequence analyses for complex human disease determinants are expanding, it seems useful to develop strategies to facilitate large data sharing, rapid replication and validation of provocative statistical associations that straddle the threshold for genome wide significance. At this conference, we shall announce GWATCH, (Genome Wide Association Tracks Chromosome Highway) a web based data release platform that can freely display and inspect unabridged genome tracked association data without compromising privacy or Informed Consent constrictions, allowing for rapid discovery and replication opportunities. We illustrate the utility with HIV-AIDS resistance genes screened in combined large multicenter cohort studies GWAS (MACS, HGDS, MHGS, ALLIVE, LSOCA HOMER) developed and studied over the last decades.
Creative Commons License
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NSUWorks Citation
O'Brien, Stephen J.; Anton Svitin; Sergey Malov; Nikolay Cherkasov; Pavel Dobrynin; Paul Geerts; Jennifer L. Troyer; Sher L. Hendrickson; Efe Sezgin; and Holli Hutcheson. 2014. "Gene Discovery and Data Sharing in Genome Wide Association Analyses: Lessons Form AIDS Genetic Restriction Genes." Journal of Acquired Immune Deficiency Syndromes 65, (Supplement 2): 59-59. https://nsuworks.nova.edu/cnso_bio_facarticles/722
Comments
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