Comparative Genomics: Lessons From Cats

Authors

• Stephen J. O'Brien, National Cancer Institute at FrederickFollow
• J. Wienberg, University of Cambridge
• Leslie A. Lyons, National Cancer Institute at Frederick

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

Trends in Genetics

ISSN

0168-9525

Publication Date

10-1997

Abstract

The genomics era, spearheaded by dazzling technological developments in human and mouse gene mapping, has additionally provoked extensive comparative gene mapping projects for domestic species of several vertebrate orders. As the human genome project promises a one dimensional string of 100 000 genes and sequences, comparative mapping will extend that inference to a second dimension representing index species of the 20 living mammalian orders and to a third dimension by phylogenetic description of the genomes of mammal ancestors. We review here the remarkable extent of genome homology conservation among mammals illustrated by technology applications in the feline genome project.

Volume

13

Issue

10

First Page

393

Last Page

400

Comments

© 1997 Published by Elsevier Ltd.

NSUWorks Citation

O'Brien, Stephen J.; J. Wienberg; and Leslie A. Lyons. 1997. "Comparative Genomics: Lessons From Cats." Trends in Genetics 13, (10): 393-400. https://nsuworks.nova.edu/cnso_bio_facarticles/688