The Promise of Comparative Genomics in Mammals

Authors

• Stephen J. O'Brien, National Cancer Institute at FrederickFollow
• Marilyn Menotti-Raymond, National Cancer Institute at Frederick
• William J. Murphy, National Cancer Institute at Frederick
• William Nash, National Cancer Institute at Frederick
• Johannes Wienberg, National Cancer Institute at Frederick
• Roscoe Stanyon, National Cancer Institute at Frederick
• Neal G. Copeland, National Cancer Institute at Frederick
• Nancy A. Jenkins, National Cancer Institute at Frederick
• James E. Womack, Texas A&M University - College Station
• Jennifer A. Marshall Graves, LaTrobe University - Melbourne, Australia

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

Science

ISSN

0036-8075

Publication Date

10-15-1999

Abstract

Dense genetic maps of human, mouse, and rat genomes that are based on coding genes and on microsatellite and single-nucleotide polymorphism markers have been complemented by precise gene homolog alignment with moderate-resolution maps of livestock, companion animals, and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species.

Volume

286

Issue

5439

First Page

458

Last Page

462, +479-481

Comments

©1999 American Association for the Advancement of Science

NSUWorks Citation

O'Brien, Stephen J.; Marilyn Menotti-Raymond; William J. Murphy; William Nash; Johannes Wienberg; Roscoe Stanyon; Neal G. Copeland; Nancy A. Jenkins; James E. Womack; and Jennifer A. Marshall Graves. 1999. "The Promise of Comparative Genomics in Mammals." Science 286, (5439): 458-462, +479-481. https://nsuworks.nova.edu/cnso_bio_facarticles/644