Biology Faculty Articles
Title
Molecular Dating and Biogeography of the Early Placental Mammal Radiation
Document Type
Article
Publication Date
3-2001
Publication Title
Journal of Heredity
ISSN
0022-1503
Volume
92
Issue/No.
2
First Page
212
Last Page
219
Abstract
The timing and phylogenetic hierarchy of early placental mammal divergences was determined based on combined DNA sequence analysis of 18 gene segments (9779 bp) from 64 species. Using rooted and unrooted phylogenies derived from distinct theoretical approaches, strong support for the divergence of four principal clades of eutherian mammals was achieved. Minimum divergence dates of the earliest nodes in the placental mammal phylogeny were estimated with a quartet-based maximum-likelihood method that accommodates rate variation among lineages using conservative fossil calibrations from nine different nodes in the eutherian tree. These minimum estimates resolve the earliest placental mammal divergence nodes at periods between 64 and 104 million years ago, in essentially every case predating the Cretaceous-Tertiary (K-T) boundary. The pattern and timing of these divergences allow a geographic interpretation of the primary branching events in eutherian history, likely originating in the southern supercontinent Gondwanaland coincident with its breakup into Africa and South America 95–105 million years ago. We propose an integrated genomic, paleontological, and biogeographic hypothesis to account for these earliest splits on the placental mammal family tree and address current discrepancies between fossil and molecular evidence.
NSUWorks Citation
Eizirik, Eduardo; William J. Murphy; and Stephen J. O'Brien. 2001. "Molecular Dating and Biogeography of the Early Placental Mammal Radiation." Journal of Heredity 92, (2): 212-219. https://nsuworks.nova.edu/cnso_bio_facarticles/615
ORCID ID
0000-0001-7353-8301
ResearcherID
N-1726-2015
Comments
©2001 The American Genetic Association