The Feline Genome Project

Authors

• Stephen J. O'Brien, National Cancer Institute at FrederickFollow
• Marilyn Menotti-Raymond, National Cancer Institute at Frederick
• William J. Murphy, National Cancer Institute at Frederick
• Naoya Yuhki, National Cancer Institute at Frederick

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

Annual Review of Genetics

ISSN

0066-4197

Publication Date

1-1-2002

Keywords

Feline, Comparative, Genome, Genetic map, Cat

Abstract

The compilation of a dense gene map and eventually a whole genome sequence (WGS) of the domestic cat holds considerable value for human genome annotation, for veterinary medicine, and for insight into the evolution of genome organization among mammals. Human association and veterinary studies of the cat, its domestic breeds, and its charismatic wild relatives of the family Felidae have rendered the species a powerful model for human hereditary diseases, for infectious disease agents, for adaptive evolutionary divergence, for conservation genetics, and for forensic applications. Here we review the advantages, rationale, and present strategy of a feline genome project, and we describe the disease models, comparative genomics, and biological applications posed by the full resolution of the cat's genome.

Volume

36

Issue

1

First Page

657

Last Page

686

Comments

©2002 Annual Reviews, Inc.

NSUWorks Citation

O'Brien, Stephen J.; Marilyn Menotti-Raymond; William J. Murphy; and Naoya Yuhki. 2002. "The Feline Genome Project." Annual Review of Genetics 36, (1): 657-686. https://nsuworks.nova.edu/cnso_bio_facarticles/606