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Biology Faculty Articles
Title
A Radiation Hybrid Mapping Panel for the Rhesus Macacque
Document Type
Article
Publication Date
11-2001
Publication Title
Journal of Heredity
ISSN
0022-1503
Volume
92
Issue/No.
6
First Page
516
Last Page
519
Abstract
The genomes of nonhuman primates have recently become highly visible candidates for full genome analysis, as they provide powerful models of human disease and a better understanding of the evolution of the human genome. We describe the creation of a 5000 rad radiation hybrid (RH) mapping panel for the rhesus macaque. Duplicate genotypes of 84 microsatellite and coding gene sequence tagged sites from six macaque chromosomes produced an estimated whole genome retention frequency of 0.33. To test the mapping ability of the panel, we constructed RH maps for macaque chromosomes 7 and 9 and compared them to orthologous locus orders in existing human and baboon maps derived from different methodologies. Concordant marker order between all three species maps suggests that the current panel represents a powerful mapping resource for generating high-density comparative maps of the rhesus macaque and other species genomes.
Additional Comments
GenBank accession #s: AF455790-AF455802
NSUWorks Citation
Murphy, William J.; J. E. Page; C. Smith Jr.; Ronald C. Desrosiers; and Stephen J. O'Brien. 2001. "A Radiation Hybrid Mapping Panel for the Rhesus Macacque." Journal of Heredity 92, (6): 516-519. https://nsuworks.nova.edu/cnso_bio_facarticles/603
ORCID ID
0000-0001-7353-8301
ResearcherID
N-1726-2015
Comments
©2001 The American Genetic Association