Title

Mapping of 53 Loci in American Mink (Mustela vison)

Authors

S. B. Kuznetsov, Institute of Cytology and Genetics - Russia; Federal University of Rio de Janeiro - Brazil
N. M. Matveeva, Institute of Cytology and Genetics - Russia
William J. Murphy, National Cancer Institute at Frederick
Stephen J. O'Brien, National Cancer Institute at FrederickFollow
O. L. Serov, Institute of Cytology and Genetics - Russia

Document Type

Article

Publication Date

9-2003

Publication Title

Journal of Heredity

ISSN

0022-1503

Volume

94

Issue/No.

5

First Page

386

Last Page

391

Abstract

Fifty-three genes were mapped in the American mink genome using polymerase chain reaction (PCR)-based analysis of a Chinese hamster–American mink somatic cell hybrid panel. Heterologous primers designed for cat gene mapping were used in this study. Forty-nine of these loci were localized into expected chromosome regions according to Zoo-FISH data, whereas four loci—ALPL, CDC20, ERF-2, and Fc(Mv)23617—were mapped out of expected conserved regions. PCR products amplified with primers corresponding to these four markers were partly sequenced and verified using BLAST. The results showed the homology to be more than 90% between mink and human or cat counterparts. At present, the gene map of American mink has expanded to 127 loci.

Comments

©2003 The American Genetic Association

Additional Comments

Russian Fund of Basic Research grant #: 01-01-48859

NSUWorks Citation

Kuznetsov, S. B.; N. M. Matveeva; William J. Murphy; Stephen J. O'Brien; and O. L. Serov. 2003. "Mapping of 53 Loci in American Mink (Mustela vison)." Journal of Heredity 94, (5): 386-391. https://nsuworks.nova.edu/cnso_bio_facarticles/583

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015