Biology Faculty Articles
Title
State of Cat Genomics
Document Type
Article
Publication Date
6-1-2008
Publication Title
Trends in Genetics
ISSN
0168-9525
Volume
24
Issue/No.
6
First Page
268
Last Page
279
Abstract
Our knowledge of cat family biology was recently expanded to include a genomics perspective with the completion of a draft whole genome sequence of an Abyssinian cat. The utility of the new genome information has been demonstrated by applications ranging from disease gene discovery and comparative genomics to species conservation. Patterns of genomic organization among cats and inbred domestic cat breeds have illuminated our view of domestication, revealing linkage disequilibrium tracks consequent of breed formation, defining chromosome exchanges that punctuated major lineages of mammals and suggesting ancestral continental migration events that led to 37 modern species of Felidae. We review these recent advances here. As the genome resources develop, the cat is poised to make a major contribution to many areas in genetics and biology.
Additional Comments
National Cancer Institute contract #: N01-CO-12400
NSUWorks Citation
O'Brien, Stephen J.; Warren E. Johnson; Carlos A. Driscoll; J. U. Pontius; Jill Pecon-Slattery; and Marilyn Menotti-Raymond. 2008. "State of Cat Genomics." Trends in Genetics 24, (6): 268-279. https://nsuworks.nova.edu/cnso_bio_facarticles/487
ORCID ID
0000-0001-7353-8301
ResearcherID
N-1726-2015
Comments
©2008 Elsevier Ltd.