Stewardship of Human Biospecimens, DNA, Genotype, and Clinical Data in the GWAS Era

Authors

• Stephen J. O'Brien, National Cancer Institute at FrederickFollow

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

Annual Review of Genomics and Human Genetics

ISSN

1527-8204

Publication Date

2009

Keywords

Biobanks, Policy, Ethics, GWAS population cohorts

Abstract

An ethical quandary is emerging over custodianship of and access to DNA specimens and attached data, clinical and genetic, held in large disease cohort collections. The balance of patients’ rights and science/society's quest for broad open access must be resolved in order to realize the promise of gene association studies of complex human disease. A way forward may be to convene a colloquium of international medical and science organizations charged with developing global consensus guidance and ethical principles for access to and use of genomic biobanks.

Volume

10

First Page

193

Last Page

209

Comments

©2009 by Annual Reviews. All rights reserved

NSUWorks Citation

O'Brien, Stephen J.. 2009. "Stewardship of Human Biospecimens, DNA, Genotype, and Clinical Data in the GWAS Era." Annual Review of Genomics and Human Genetics 10, (): 193-209. https://nsuworks.nova.edu/cnso_bio_facarticles/466