The Human Homolog of the Moloney Leukemia Virus Integration 2 Locus (MLVI2) Maps to Band p14 of Chromosome 5

Authors

• Nicholas P. Anagnou, University of Crete - Greece; Foundation for Research and Technology - Greece
• Agathe Economou-Pachnis, Fox Chase Cancer Center
• Stephen J. O'Brien, National Cancer Institute at FrederickFollow
• William S. Modi, National Cancer Institute at Frederick
• Arthur W. Nienhuis, National Heart, Lung, and Blood Institute
• Philip N. Tsichlis, Fox Chase Cancer Center

ORCID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Document Type

Article

Publication Title

Genomics

ISSN

0888-7543

Publication Date

8-1989

Abstract

The Moloney leukemia virus integration 2 (MLVI2) locus represents a common region for proviral integration and a putative oncogene involved in the induction of thymic lymphomas in rodents. The human homolog of the MLVI2 locus has been cloned and studies have been intiated to determine its possible role in the induction and progression of human neoplasms. In this study we used a panel of human × rodent somatic cell hybrids and in situ hybridization to metaphase chromosomes to map MLVI2 to the short arm of the human chromosome 5, band p14.

Volume

5

Issue

2

First Page

354

Last Page

358

Comments

© 1989 Published by Elsevier Inc.

NSUWorks Citation

Anagnou, Nicholas P.; Agathe Economou-Pachnis; Stephen J. O'Brien; William S. Modi; Arthur W. Nienhuis; and Philip N. Tsichlis. 1989. "The Human Homolog of the Moloney Leukemia Virus Integration 2 Locus (MLVI2) Maps to Band p14 of Chromosome 5." Genomics 5, (2): 354-358. https://nsuworks.nova.edu/cnso_bio_facarticles/345