Title

The Human Homolog of the Moloney Leukemia Virus Integration 2 Locus (MLVI2) Maps to Band p14 of Chromosome 5

Authors

Nicholas P. Anagnou, University of Crete - Greece; Foundation for Research and Technology - Greece
Agathe Economou-Pachnis, Fox Chase Cancer Center
Stephen J. O'Brien, National Cancer Institute at FrederickFollow
William S. Modi, National Cancer Institute at Frederick
Arthur W. Nienhuis, National Heart, Lung, and Blood Institute
Philip N. Tsichlis, Fox Chase Cancer Center

Document Type

Article

Publication Date

8-1989

Publication Title

Genomics

ISSN

0888-7543

Volume

5

Issue/No.

2

First Page

354

Last Page

358

Abstract

The Moloney leukemia virus integration 2 (MLVI2) locus represents a common region for proviral integration and a putative oncogene involved in the induction of thymic lymphomas in rodents. The human homolog of the MLVI2 locus has been cloned and studies have been intiated to determine its possible role in the induction and progression of human neoplasms. In this study we used a panel of human × rodent somatic cell hybrids and in situ hybridization to metaphase chromosomes to map MLVI2 to the short arm of the human chromosome 5, band p14.

Comments

© 1989 Published by Elsevier Inc.

NSUWorks Citation

Anagnou, Nicholas P.; Agathe Economou-Pachnis; Stephen J. O'Brien; William S. Modi; Arthur W. Nienhuis; and Philip N. Tsichlis. 1989. "The Human Homolog of the Moloney Leukemia Virus Integration 2 Locus (MLVI2) Maps to Band p14 of Chromosome 5." Genomics 5, (2): 354-358. https://nsuworks.nova.edu/cnso_bio_facarticles/345

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015