Dispermic origin and clinical outcome of three complete hydatidiform moles with 46,XY karyotype
American Journal of Obstetrics and Gynecology
Three new cases of complete, classic hydatidiform mole with a 46,XY karyotype are described. They originated by dispermy as demonstrated by chromosome and enzyme analyses. Levels of human chorionic gonadotropin decreased to normal spontaneously within a short time, indicating a benign course in these three cases. Of a total of 18 cases reported to date, postoperative clinical information was available for 10 patients. Two of these 10 patients had a malignant course with lung metastases. It is of theoretical and clinical importance to establish the magnitude of the risk of malignancy for hydatidiform mole with a 46,XY karyotype. © 1982.
Surti, U.; A. E. Szulman; and S. O'Brien. 1982. "Dispermic origin and clinical outcome of three complete hydatidiform moles with 46,XY karyotype." American Journal of Obstetrics and Gynecology 144, (1): 84-87. doi:10.1016/0002-9378(82)90399-4.