Title

AIDS: A role for host genes

Authors

Stephen J. O'brien, National Cancer Institute (NCI)Follow

Document Type

Article

Publication Date

7-15-1998

Publication Title

Hospital Practice

Volume

33

Issue/No.

7

First Page

53

Last Page

79

Abstract

Suspicion that human genes affect the natural history of AIDS has been confirmed by discoveries of three such genes, one of which comers near-total immunity ha about 1% of Caucasians. The findings suggest a novel therapeutic target: not HIV but the host's cooperation with it. They also herald an era in which genomes are seen as having been shaped by the evolutionary pressures of infection, and may thus hold evolution-tested therapies.

NSUWorks Citation

O'brien, Stephen J.. 1998. "AIDS: A role for host genes." Hospital Practice 33, (7): 53-79. doi:10.3810/hp.1998.07.96.

DOI

10.3810/hp.1998.07.96