Title

Comparative Chromosome Mapping of Musk Ox and the X Chromosome among Some Bovidae Species

Authors

Anastasiya A. Proskuryakova, Institute of Molecular and Cell Biology - Novosibirsk, Russia
Anastasia I. Kulemzina, Institute of Molecular and Cell Biology - Novosibirsk, Russia
Polina L. Perelman, Institute of Molecular and Cell Biology - Novosibirsk, Russia; Novosibirsk State University - Russia
Dmitry V. Yudkin, Federal Service for Surveillance on Consuemr Rights Protection and Human Well-Being - Koltsovo, Russia
Natalya A. Lemskaya, Institute of Molecular and Cell Biology - Novosibirsk, Russia; Federal Service for Surveillance on Consuemr Rights Protection and Human Well-Being - Koltsovo, Russia
Innokentii M. Okhlopkov, Institute for Biological Problems of Cryolithozone Siberian Branch of RAS - Russia
Egor V. Kirillin, Institute for Biological Problems of Cryolithozone Siberian Branch of RAS - Russia
Marta Farré, University of London - United Kingdom; University of Kent - United Kingdom
Denis M. Larkin, University of London - United Kingdom
M. Roelke-Parker, National Cancer Institute at Frederick
Stephen James O'Brien, Saint Petersburg State University - Russia; Nova Southeastern UniversityFollow
Mitchell Bush, Smithsonian Institution
Alexander S. Graphodatsky, Institute of Molecular and Cell Biology - Novosibirsk, Russia; Novosibirsk State University - Russia

Document Type

Article

Publication Date

11-2019

Publication Title

Genes

Keywords

BAC-clones, Chromosome painting, Kirk's dikdik, Musk ox, Saola, Nilgai bull, Gaur

ISSN

2073-4425

Volume

10

Issue/No.

11

First Page

1

Last Page

14

Abstract

Bovidae, the largest family in Pecora infraorder, are characterized by a striking variability in diploid number of chromosomes between species and among individuals within a species. The bovid X chromosome is also remarkably variable, with several morphological types in the family. Here we built a detailed chromosome map of musk ox (Ovibos moschatus), a relic species originating from Pleistocene megafauna, with dromedary and human probes using chromosome painting. We trace chromosomal rearrangements during Bovidae evolution by comparing species already studied by chromosome painting. The musk ox karyotype differs from the ancestral pecoran karyotype by six fusions, one fission, and three inversions. We discuss changes in pecoran ancestral karyotype in the light of new painting data. Variations in the X chromosome structure of four bovid species nilgai bull (Boselaphus tragocamelus), saola (Pseudoryx nghetinhensis), gaur (Bos gaurus), and Kirk’s Dikdik (Madoqua kirkii) were further analyzed using 26 cattle BAC-clones. We found the duplication on the X in saola. We show main rearrangements leading to the formation of four types of bovid X: Bovinae type with derived cattle subtype formed by centromere reposition and Antilopinae type with Caprini subtype formed by inversion in XSB1.

Comments

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

Additional Comments

Russian Science Foundation grant #: 19-14-00034; Biotechnology and Biological Sciences Research Council grant #: BB/P020062/1; Russian Foundation for Basic Research grant #: 17-00-00145

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

NSUWorks Citation

Proskuryakova, Anastasiya A.; Anastasia I. Kulemzina; Polina L. Perelman; Dmitry V. Yudkin; Natalya A. Lemskaya; Innokentii M. Okhlopkov; Egor V. Kirillin; Marta Farré; Denis M. Larkin; M. Roelke-Parker; Stephen James O'Brien; Mitchell Bush; and Alexander S. Graphodatsky. 2019. "Comparative Chromosome Mapping of Musk Ox and the X Chromosome among Some Bovidae Species." Genes 10, (11): 1-14. doi:10.3390/genes10110857.

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015

DOI

10.3390/genes10110857