Metal Redistribution in Largemouth Bass (Micropterus salmoides) in Response to Restrainment Stress and Dietary Cadmium: Role of Metallothionein and Other Metal-Binding Proteins

Authors

Daniel N. Weber, University of Wisconsin - MilwaukeeFollow
Sara Eisch, St. Norbert College
Richard E. Spieler, University of Wisconsin - Milwaukee; Milwaukee Public MuseumFollow
David H. Petering, University of Wisconsin-Milwaukee

Document Type

Article

Publication Title

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

ISSN

0306-4492

Publication Date

2-1992

Keywords

Cadmium/administration & dosage, Bass/metabolism, Animals, Cadmium/pharmacology, Copper/metabolism, Stress, Zinc, Hydrocortisone, Intestines, Muscles, Ovary, Tissue Distribution

Abstract

1. Fish stressed by restrainment displayed elevated serum cortisol, copper and zinc levels; dietary cadmium had no effect.

2. Stress/dietary cadmium increased liver copper levels in a metal pool containing metallothionein and non-metallothionein proteins but decreased intestinal zinc bound as low molecular weight forms.

3. After restrainment, zinc losses occurred in dorsal skeletal muscle, ovary and spleen: copper decreased in intestine and pyloric caecum.

4. Dietary cadmium altered intestinal zinc distribution and raised hepatic Cu-binding protein levels but did not alter plasma zinc, copper or cortisol levels.

5. Alterations in zinc and copper concentrations during stress contrast with mammalian models.

DOI

10.1016/0742-8413(92)90270-H

Volume

101

Issue

2

First Page

255

Last Page

262

Comments

©1992 Published by Elsevier Inc.

Additional Comments

Grant Support

• ES 04184/ES/NIEHS NIH HHS/United States
• RR-03326/RR/NCRR NIH HHS/United States

NSUWorks Citation

Daniel N. Weber, Sara Eisch, Richard E. Spieler, and David H. Petering. 1992. Metal Redistribution in Largemouth Bass (Micropterus salmoides) in Response to Restrainment Stress and Dietary Cadmium: Role of Metallothionein and Other Metal-Binding Proteins .Comparative Biochemistry and Physiology Part C: Comparative Pharmacology , (2) : 255 -262. https://nsuworks.nova.edu/occ_facarticles/181.