Marine & Environmental Sciences Faculty Articles

Metal Redistribution in Largemouth Bass (Micropterus salmoides) in Response to Restrainment Stress and Dietary Cadmium: Role of Metallothionein and Other Metal-Binding Proteins

Document Type

Article

Publication Date

2-1992

Publication Title

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

Keywords

Cadmium/administration & dosage, Bass/metabolism, Animals, Cadmium/pharmacology, Copper/metabolism, Stress, Zinc, Hydrocortisone, Intestines, Muscles, Ovary, Tissue Distribution

ISSN

0306-4492

Volume

101

Issue/No.

2

First Page

255

Last Page

262

Abstract

1. Fish stressed by restrainment displayed elevated serum cortisol, copper and zinc levels; dietary cadmium had no effect.

2. Stress/dietary cadmium increased liver copper levels in a metal pool containing metallothionein and non-metallothionein proteins but decreased intestinal zinc bound as low molecular weight forms.

3. After restrainment, zinc losses occurred in dorsal skeletal muscle, ovary and spleen: copper decreased in intestine and pyloric caecum.

4. Dietary cadmium altered intestinal zinc distribution and raised hepatic Cu-binding protein levels but did not alter plasma zinc, copper or cortisol levels.

5. Alterations in zinc and copper concentrations during stress contrast with mammalian models.

Comments

©1992 Published by Elsevier Inc.

DOI

10.1016/0742-8413(92)90270-H

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