Faculty Articles
Regional Cerebral Blood Flow in Schizophrenics. Tests Using the Xenon Xe 133 Inhalation Method.
Document Type
Article
Publication Date
3-1983
Publication Title
Archives of General Psychiatry
Volume
40
Issue/Number
3
First Page
258
ISSN
0003-990X
Last Page
263
Abstract/Excerpt
Measurements of intrahemispheric and bilateral regional cerebral blood flow (CBF) for gray and white matter were compared in 29 schizophrenic patients and 22 normal controls, using the xenon Xe 133 inhalation method. Results showed significantly lower CBF values for all brain regions in the schizophrenic group, and post hoc comparisons showed relatively greater reduced gray-matter CBF values in the anterior areas of the brain. There was also a left-hemisphere frontal loss similar to that reported previously, although it was in the context of a generalized loss in anterior functioning. Interhemispheric comparison within both groups showed no differences between homologous regions for gray matter, and greater white-matter CBF values in the right hemisphere than in the left hemisphere. The findings support a hypothesis of a bilateral anterior deficit in schizophrenia.
DOI
10.1001/archpsyc.1983.01790030028003
NSUWorks Citation
Ariel, R. N.,
Golden, C. J.,
Berg, R. A.,
Quaife, M.,
Dirksen, J. W.,
Forsell, T.,
Wilson, J.,
Graber, B.
(1983). Regional Cerebral Blood Flow in Schizophrenics. Tests Using the Xenon Xe 133 Inhalation Method.. Archives of General Psychiatry, 40(3), 258-263.
Available at: https://nsuworks.nova.edu/cps_facarticles/760