Faculty Articles
Aging, Regional Cerebral Blood Flow, and Neuropsychological Functioning.
Document Type
Article
Publication Title
Journal of the American Geriatrics Society
ISSN
0002-8614
Publication Date
10-1984
Abstract
Previous studies found changes in regional cerebral blood flow (rCBF) patterns related to both age and various cognitive tasks. However, no study has yet demonstrated a relationship between rCBF and performance on the Luria-Nebraska Neuropsychological Battery (LNNB) in an elderly group. Seventy-nine elderly volunteers (56-88 years old), both healthy and demented, underwent the 133xenon inhalation rCBF procedure and were given the LNNB. The decrements in the gray-matter blood flow paralleled decrements in performance on the LNNB. Using partial correlations, a significant proportion of shared variance was observed between gray-matter blood flow and the LNNB scales. However, there was much less of a relationship between white-matter blood flow and performance on the LNNB. This study suggests that even within a restricted age sample rCBF is related in a global way to neuropsychological functioning.
Volume
32
Issue
10
First Page
712
Last Page
718
NSUWorks Citation
MacInnes, W. D.,
Golden, C. J.,
Gillen, R. W.,
Sawicki, R. F.,
Quaife, M.,
Uhl, H. S.,
Greenhouse, A. H.
(1984). Aging, Regional Cerebral Blood Flow, and Neuropsychological Functioning.. Journal of the American Geriatrics Society, 32(10), 712-718.
Available at: https://nsuworks.nova.edu/cps_facarticles/650