Faculty Articles

Cognitive Rehabilitation of Mildly Impaired Alzheimer's Disease Patients On Cholinesterase Inhibitors

Document Type

Article

Publication Title

The American Journal of Geriatric Psychiatry

ISSN

1064-7481

Publication Date

Summer 2004

Abstract

The authors evaluated the efficacy of a new cognitive rehabilitation program on memory and functional performance of mildly impaired Alzheimer disease (AD) patients receiving a cholinesterase inhibitor. Twenty-five participants in the Cognitive Rehabilitation (CR) condition participated in two 45-minute sessions twice per week for 24 total sessions. CR training included face-name association tasks, object recall training, functional tasks (e.g., making change, paying bills), orientation to time and place, visuo-motor speed of processing, and the use of a memory notebook. Nineteen participants in the Mental Stimulation (MS) condition had equivalent therapist contact and number of sessions, which consisted of interactive computer games involving memory, concentration, and problem-solving skills. Compared with the MS condition, participants in CR demonstrated improved performance on tasks that were similar to those used in training. Gains in recall of face-name associations, orientation, cognitive processing speed, and specific functional tasks were present post-intervention and at a 3-month follow-up. A systematic program of cognitive rehabilitation can result in maintained improvement in performance on specific cognitive and functional tasks in mildly impaired AD patients.

DOI

10.1097/00019442-200407000-00007

Volume

12

Issue

4

First Page

395

Last Page

402

Peer Reviewed

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