Title of Project

Analysis of D1S80 Locus, an introductory Bioinformatics analysis study in Human Genotype

Researcher Information

Ana Paula Delgado

Project Type

Event

Start Date

2011 12:00 AM

End Date

2011 12:00 AM

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Analysis of D1S80 Locus, an introductory Bioinformatics analysis study in Human Genotype

DNA profile analysis focuses on hyper variable regions of DNA. This project seeks to study a specific variability called VNTR (variable number of tandem repeats). DNA sequencing data of D1S80 locus was obtained from individuals from African American, Caucasian, and Hispanic databases was analyzed. The data collected had been previously processed by PCR and DNA cloning using E. Coli. This data was provided by Dr. Duncan from the Broward’s Sheriff Lab. The study demonstrated that variation of D1S80 alleles are predominantly due to the number of repeat units contained within the amplicons obtained from PCR. Also, it was demonstrated that this type of micro variation can be the result of mutations such as insertion and deletions.