Simvastatin and Oncolytic Vesicular Stomatitis Virus Actions on HeLa Cells
Current Topics in Pharmacology
Publication Date / Copyright Date
Research Trends (P) Ltd.
Statins, the cholesterol-lowering drugs, are known to exert pleiotropic actions including anticancer and antiviral effects. The interaction between simvastatin and oncolytic vesicular stomatitis virus (VSV), a potential candidate for anticancer therapy, was investigated. HeLa cells in culture were exposed to simvastatin and/or VSV-green fluorescence protein (GFP) at different times and concentrations.
Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences
antiviral, apoptosis, simvastatin, vesicular stomatitis virus
Faria-Waziry, Paula A.; Puerta, Francisco; Rottaro, Giulio; Castejon, Ana M.; and Cubeddu, Luigi X., "Simvastatin and Oncolytic Vesicular Stomatitis Virus Actions on HeLa Cells" (2017). Faculty Articles. 274.