Faculty Articles

Title

Simvastatin and Oncolytic Vesicular Stomatitis Virus Actions on HeLa Cells

Publication Title

Current Topics in Pharmacology

Volume

21

Publication Date / Copyright Date

2017

First Page

17

Last Page

25

Publisher

Research Trends (P) Ltd.

Abstract

Statins, the cholesterol-lowering drugs, are known to exert pleiotropic actions including anticancer and antiviral effects. The interaction between simvastatin and oncolytic vesicular stomatitis virus (VSV), a potential candidate for anticancer therapy, was investigated. HeLa cells in culture were exposed to simvastatin and/or VSV-green fluorescence protein (GFP) at different times and concentrations.

Disciplines

Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences

Keywords

antiviral, apoptosis, simvastatin, vesicular stomatitis virus

Peer Reviewed

Find in your library

Share

 
COinS