Department of Nutrition Student Projects

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Submission Date


Document Type


Degree Name

Master of Nutrition Science (MS)

First Mentor

Anne Davis, PhD, MS, RDN, LDN, FAND


Deutenomics, mitochondria, health, ketogenic diet, cancer, disease, nutrition, diabetes, metabolic water


Background: Deuterium depletion is an untapped area of energy metabolism and health.

Objectives: The purpose of this scoping review is to examine the health effects through deuterium depletion via deuterium-depleted water and a deuterium-depleted diet (ketogenic).

Methods: A protocol process approach was used to retrieve current research in deuterium depletion.

Results: 15 research articles were used. Deuterium depletion was found to have beneficial health effects in the following conditions: cancer prevention, cancer treatment, depression, diabetes, long-term memory, anti-aging, and sports performance.

Conclusion: Even with limited data, consistent deuterium depletion was seen across all conditions reviewed. More randomized control trials are recommended to confirm cause and effect.