Capstone Title

Ciguatera Fish Poisoning: Origin and Chemistry of Toxins, Pharmacology in Mammalian Systems, and Public Health Impacts in the Caribbean

Defense Date


Document Type


Degree Name

M.S. Marine Biology

First Advisor

Richard Spieler

Second Advisor

Richard E. Dodge


Statement of Purpose

Ciguatera is a unique problem that has remained elusive to researchers for the last several decades. Investigations into ciguatera have involved the work of researchers from several different disciplines, including marine scientists, chemists, botanists, ichthyologists, pharmacologists, physicians, and epidemiologists. The purpose of this paper is to provide a review of the ecology of ciguatera production and transmission, the primary modes of action of ciguatera toxins in humans, and the impacts of ciguatera on public health in areas where it is endemic.

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