Biology Faculty Articles
Large Sequence Divergence Among Mitochondrial DNA Genotypes Within Populations of Eastern African Black-Backed Jackals
Proceedings of the National Academy of Sciences of the United States of America
Canidae, Genetic variability, Intraspecific phylogeny
In discussions about the relative rate of molecular evolution, intraspecific variability in rate is rarely considered. An underlying assumption is that intraspecific sequence differences are small, and thus variations in rate would be difficult to detect or would not affect comparisons among distantly related taxa. However, several studies on mammalian mitochondrial DNA (mtDNA) have revealed considerable intraspecific sequence divergence. In this report, we test for differences in the rate of intraspecific evolution by comparing mtDNA sequences, as inferred from restriction site polymorphisms and direct sequencing, between mtDNA genotypes of the eastern African black-backed jackal, Canis mesomelas elongae, and those of two other sympatric jackal species. Our results are unusual for several reasons. First, mtDNA sequence divergence within several contiguous blackbacked jackal populations is large (8.0%). Previous intraspecific studies of terrestrial mammals have generally found values of
Wayne, Robert K.; A. Meyer; N. Lehman; B. Van Valkenburgh; P. W. Kat; T. K. Fuller; D. Girman; and Stephen J. O'Brien. 1990. "Large Sequence Divergence Among Mitochondrial DNA Genotypes Within Populations of Eastern African Black-Backed Jackals." Proceedings of the National Academy of Sciences of the United States of America 87, (5): 1772-1776. https://nsuworks.nova.edu/cnso_bio_facarticles/239
Grants from the National Science Foundation, National Institutes of Health, and the Keck Fellowship.