Biology Faculty Articles
Title
The 14-3-3 (YWHA) Proteins in Signalling and Development of the Fruit Fly, Drosophila melanogaster
Document Type
Article
Publication Date
12-8-2019
Publication Title
International Annals of Science
Keywords
14-3-3, YWHA, Drosophila, Signaling, Development
ISSN
2456-7132
Volume
9
Issue/No.
1
First Page
80
Last Page
85
Abstract
The 14-3-3 (YWHA or Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation proteins) are a family of highly conserved, homologous proteins critical to diverse cellular events including cell cycle, signal transduction and embryonic development. Various species-specific isoforms of 14-3-3 exist, encoded by separate genes. They are expressed in a wide variety of organisms ranging from plants to animals, including the fruit fly or Drosophila melanogaster. Drosophila is one of the most universally accepted model systems to study complex cellular mechanisms of signalling and development. However, regulation of these processes in fruit flies by the 14-3-3 proteins have not been entirely understood. This mini review encapsulates the expression, distribution, interactions and regulatory roles of the 14-3-3 proteins in Drosophila. The analysis would help to elucidate some of the molecular bases of key cell-signalling mechanisms and development.
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
NSUWorks Citation
De, Santanu. 2019. "The 14-3-3 (YWHA) Proteins in Signalling and Development of the Fruit Fly, Drosophila melanogaster." International Annals of Science 9, (1): 80-85. doi:10.21467/ias.9.1.80-85.
ORCID ID
0000-0002-9739-4039
DOI
10.21467/ias.9.1.80-85
Comments
Copyright © 2019. The Author(s). Published by AIJR Publisher. This is an open access article under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits any non-commercial use, distribution, adaptation, and reproduction in any medium, as long as the original work is properly cited.