Chemistry and Physics Faculty Proceedings, Presentations, Speeches, Lectures

Title

Oxidative Deamination of Amino Acids by Molecular Oxygen with Pyridoxal Phosphate and Cu(II) Ion as Catalysts

Event Name/Location

8th International Symposium on Vitamin B6 and Carbonyl Catalysis, Osaka, Japan, October 15-19, 1990

Document Type

Conference Proceeding

Publication Date

1991

Keywords

Oxidative deamination, Pyridoxal phosphate, p-suifophenylglycine, Oxygen insertion, Oxime formation, Monooxygenase model

Abstract

This paper reports the quantitative oxidation by molecular oxygen of the Cu(II) chelate of the Schiff base formed from vitamin B6 (pyridoxal phosphate, PLP) and p-sulfophenylglycine to the keto acid, p-sulfophenyl-glyoxylic acid, and the Cu(II) chelate of PLP oxime. In the presence of excess amino acid the Cu(II) chelate of the oxime becomes an intermediate in the oxidative deamination of the amino acid to the corresponding keto acid and ammonia, with Cu(II) and PLP as catalysts.

Comments

© 1991 Pergamon Press plc. Published by Elsevier Ltd. All rights reserved.

Conference Proceeding Title

Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds As Cofactors

ISBN

978-0-08-040820-0

Publisher

Pergamon Press

DOI

10.1016/B978-0-08-040820-0.50078-9

First Page

365

Last Page

369

This document is currently not available here.

Share

COinS