Journey or the Milestones: Epigenetic Changes as Timestamp Along the Way of Human Evolution
Author Bio(s)
Malav Trivedi, Ph.D., is an assistant professor at NSU’s College of Pharmacy. He has authored several manuscripts implicating the role of metabolic changes and epigenetic-based gene expression changes in neurodevelopmental and neuropsychiatric disorders. His continuing preclinical and clinical research indicates that opioids and food-derived opioid peptides induce oxidative stress and epigenetic changes. This can affect inflammatory status and potentially contribute to gastrointestinal and neurological manifestations. Exemplifying the university’s multidisciplinary approach to research and collaboration, Trivedi’s work includes the fields of molecular biology, nutritional biochemistry, pharmacology, and neuroscience. His research interests also include mitochondrionomics, epigenetic and transcriptional changes in neurodevelopmental disorders (e.g., Autism), drug addiction and withdrawal, neurodegenerative diseases (i.e., Alzheimer’s and Parkinson’s), and tumor biology and the microenvironment. Trivedi has developed a unique skill set and expertise in the research community; is involved in several regional, national, and international collaborations; and receives grant support for his work.
Talk Description
Epigenetic changes are an epi-phenomenon that happens on—not in—the genetic code of an individual. These marks regulate cellular and physiological phenotypic trait variations caused by external or environmental factors, which switches genes on and off without changes in the DNA sequence throughout evolution. Epigenetic changes may not only serve as a memory timestamp for the day-to-day lifestyle of an individual, but are also an evolutionary timestamp and have contributed to who we are as a species.
Recommended Citation
Trivedi, Ph.D., Malav, "Journey or the Milestones: Epigenetic Changes as Timestamp Along the Way of Human Evolution" (2016). TEDxNSU. 17.
https://nsuworks.nova.edu/tedxnsu/17
