Recovery of binocular responses by cortical neurons after early monocular lesions
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A small lesion of the retina in one eye deprives normally binocular neurons in a sector of primary visual cortex of activating inputs from the lesioned eye, but not from the other, intact eye. Here we demonstrate that after monocular lesions early in life followed by years of recovery, deprived cortical neurons become robustly responsive to stimulation via new receptive fields in a zone of preserved retina around the retinal lesion, while maintaining receptive fields for the intact eye. These neurons respond similarly to comparable stimuli in two different locations, possibly producing a local diplopia or blur.
Chino, Yuzo M.; Smith, Earl L. III; Zhang, Bin; Matsuura, Kazuki; Mori, Takafumi; and Kaas, Jon H., "Recovery of binocular responses by cortical neurons after early monocular lesions" (2001). Faculty Articles. 3.