Department of Health Sciences Faculty Articles

Title

Disseminated Conidiobolus Infection With Endocarditis in a Cocaine Abuser.

ISBN or ISSN

0003-9985

Volume

114

Issue

12

Publication Date / Copyright Date

12-1990

First Page

1276

Last Page

1278

Publisher

College of American Pathologists

Abstract

A crack cocaine abuser developed disseminated infection caused by a species of Conidiobolus not known to cause disease in vertebrates. The fungus gained entry via skin abrasions on the lower extremities, spread through the hematogenous route, and caused endocarditis. There was evidence of fungal infection in the lungs, heart, kidneys, skeletal muscles, and brain. An additional complication was extensive rhabdomyolysis, with a marked elevation of creatine kinase of up to 1.2 million U/L.

Disciplines

Medicine and Health Sciences

Keywords

Cocaine, Endocarditis, Entomophthora, Mycoses, Substance-Related Disorders

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