Medical & Clinical Case Reports Journal
Androgenetic alopecia, Platelet-rich plasma, Randomized controlled trials
Androgenetic Alopecia (AGA), the most common form of hair loss in both males and females, is characterized by the progression of large, pigmented terminal hair to thin, fine vellus hair. In recent years, there has been growing interest in exploring Platelet-Rich Plasma (PR) as a therapeutic option for AGA. PRP is a mixture of numerous cytokines and growth factors that have shown the ability to facilitate wound healing and collagen development. PRP is a mixture of numerous cytokines and growth factors that have shown the ability to facilitate wound healing and collagen development. Utilizing the databases PubMed, Medline EBSCO, and CINAHL, a comprehensive search was performed to identify studies that demonstrated whether PRP is effective in treating androgenic alopecia by increasing the hair density, thickness, or width of the area. We included studies published from 2016 to 2023 based on the inclusion criteria as follows: as follows: (1) adults 19+ years of age, (2) fully accessible texts, (3) English language (4) published between 2016-2023, (5) androgenic alopecia (6) controlled with a saline injection group,
(7) articles on human subjects. The results showed a statistically significant increase in hair density with the PRP treatment compared to baseline. However, when compared to the placebo, most studies were insignificant. These studies also showed improvement in hair diameter or caliber. The current data involving randomized controlled trials (RCTs) is limited and further RCTs need to be performed to establish a correlation.
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Kunder, Viktor; Munoz, Cristina; and Palonpon, Judd Ivan, "Platelet-Rich Plasma’s Effects in Patients with Androgenetic Alopecia: A Scoping Review" (2023). HPD Articles. 359.
© 2023 Kunder, V., et al.