carcinoid-triggered fibrosis, valvular prosthesis, valvular fibrosis, quadruple valve replacement, carcinoid heart disease
This report details a rare case of left-sided carcinoid heart disease (CHD). In CHD, vasoactive substances released from carcinoid tumors cause fibrous tissue formation on the right side of the heart. These substances are usually inactivated by monoamine oxidase A in the lungs, safeguarding the left side of the heart. Exceptions include the presence of a patent foramen ovale (PFO), pulmonary metastasis, or elevated serotonin levels. Intriguingly, our patient exhibited significant left-sided involvement without these factors, ultimately requiring a quadruple valve replacement surgery. After eight months post-operation, the patient is stable with no cardiovascular complications. This rare case of CHD, along with its outcome, hints at potential unidentified etiologies for left-sided CHD and underscores valve replacement as a viable treatment.
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Beyer, Maria; Kasarla, Rishabh; Shoap, Seth; and Beyer, Erik, "Quadruple Valve Replacement in Carcinoid Heart Disease: A Case Report" (2023). HPD Articles. 287.
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