Faculty Books and Book Chapters

Neuronal Hormones and the Sympathetic/Parasympathetic Regulation of the Heart

Neuronal Hormones and the Sympathetic/Parasympathetic Regulation of the Heart

ISBN or ISSN

978-0-12-803111-7

Chapter

8

Publication Date / Copyright Date

2016

First Page

207

Last Page

227

Publisher

Elsevier Academic Press

DOI Number

10.1016/C2014-0-04170-6

Abstract

The primary purpose of the heart is to contract and pump blood to the entire body and all peripheral organs. Heart rate and cardiac output are tightly regulated so the heart can adjust to meet the needs of the organism under any given circumstance. This regulation is provided by the autonomic nervous system, including hormones and other secreted factors. In this chapter, we discuss the physiological mechanisms by which cardiac function is controlled and modulated by the autonomic (sympathetic & parasympathetic) nervous system, by the endocrine organs (mainly pituitary and adrenal glands), and, finally, by its own intrinsic endocrine system (cardiac hormones). Particular emphasis is given to molecular receptor signaling mechanisms underlying these processes.

Disciplines

Medicine and Health Sciences | Pharmacy and Pharmaceutical Sciences

Keywords

autonomic nervous system, cardiac function, molecular receptor signaling mechanisms

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Neuronal Hormones and the Sympathetic/Parasympathetic Regulation of the Heart
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