Prevalence and correlates of Capgras syndrome in Alzheimer's disease.
ISBN or ISSN
International journal of geriatric psychiatry
Publication Date / Copyright Date
OBJECTIVES: This study examined the prevalence and clinical correlates of Capgras syndrome (CS) in Alzheimer's disease.
DESIGN: Cross-sectional study of elderly patients evaluated at an outpatient memory disorders clinic classified according to the presence or absence of CS.
SUBJECTS: One hundred and fifty-one consecutive patients diagnosed with probable (N=110) or possible (N=48) Alzheimer's disease (AD) utilizing NINCDS-ADRDA diagnostic criteria.
MATERIALS: The Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD), Mini-Mental State Examination (MMSE) and Blessed Dementia Scale (BDS).
RESULTS: CS was observed in 10% of the sample (N=16). Associated factors included other delusions, lower MMSE scores and higher BDS scores. The relation between CS and both cognitive and functional status remained significant after controlling for other delusions.
CONCLUSION: CS was prevalent in approximately 10% of our community-dwelling AD sample. This syndrome was more common at the later stages of the illness and showed relations with increased functional impairment and other psychotic symptomatology.
Medical Specialties | Medicine and Health Sciences | Osteopathic Medicine and Osteopathy
Aged, Aged, 80 and over, Alzheimer Disease, Capgras Syndrome, Cognition Disorders, Cross-Sectional Studies, Delusions, Disease Progression, Female, Humans, Incidence, Male, Outpatients, Prevalence, Psychiatric Status Rating Scales
Harwood, Dylan G.; Barker, Warren W.; Ownby, Raymond L.; and Duara, Ranjan, "Prevalence and correlates of Capgras syndrome in Alzheimer's disease." (1999). College of Osteopathic Medicine Faculty Articles. 52.