Are Molecules Involved in Neuritogenesis and Axon Guidance Related to Autism Pathogenesis?, Jan Bakos, Zuzana Bacova, Stephen G. Grant, Ana Maria Castejon, Ostatnikova Daniela
Faculty Articles

Regulation and Disregulation of Mammalian Nucleotide Excision Repair: A Pathway to Nongermline Breast Carcinogenesis, Jean Johanna Latimer, Vongai J. Majekwana, Yashira R. Pabón-Padín, Manasi R. Pimpley, Stephen G. Grant
Faculty Articles

ELEVATED EXPRESSION OF NUCLEOTIDE EXCISION REPAIR GENES UPON RELAPSE OF ACUTE LYMPHOCYTIC LEUKEMIA, Stephen G. Grant, Omar Ibrahim, Homood As Sobeai, Jean J. Latimer
Health Professions Division REACH Day

WNT10B/β-catenin Signalling Induces HMGA2 and Proliferation in Metastatic Triple-negative Breast Cancer, Peter Wend, Stephanie Runke, Korinna Wend, Brenda Anchondo, Maria Yesayan, Meghan Jardon, Natalie Hardie, Christoph Loddenkemper, Ilya Ulasov, Maciej S. Lesniak, Rebecca Wolsky, Laurent A. Bentolila, Stephen G. Grant, David Elashoff, Stephan Lehr, Jean J. Latimer, Shikha Bose, Hussain Sattar, Susan A. Krum, Gustavo A. Miranda-Carboni
Faculty Articles

Translating Mutagenesis into Carcinogenesis, Stephen G. Grant
Faculty Articles

Active and Passive Tobacco Smoke Exposure Cause DNA Damage and Increased Cancer Risk Beginning in the Womb, Stephen G. Grant
Health Professions Division REACH Day

The Context for Ancestry in the Breast Cancer Stem Cell Paradigm, Jean J. Latimer, Nicole T. Myers, Stephen G. Grant
Health Professions Division REACH Day

Mutational Biomonitoring of Breast Cancer Chemotherapy Patients Reveals Dichotomy in Bone Marrow Response, Stephen G. Grant, Nicole T. Myers, Joseph L. Kelley, Victor G. Vogel
Health Professions Division REACH Day

Identification of Hydroxysteroid (17β) Dehydrogenase Type 12 (HSD17B12) as a CD8+ T-cell-defined Human Tumor Antigen of Human Carcinomas, Carmen Visus, Diasuke Ito, Rajiv Dhir, Miroslaw J. Szcezepanski, Yoo Jung Chang, Jean J. Latimer, Stephen G. Grant, Albert B. DeLeo
Faculty Articles

Nucleotide Excision Repair Deficiency is Intrinsic in Sporadic Stage I Breast Cancer, Jean J. Latimer, Jennifer M. Johnson, Crystal M. Kelly, Tiffany D. Miles, Kelly A. Beaudry-Rodgers, Nancy A. Lalanne, Victor G. Vogel, Amal Kanbour-Shakir, Joseph L. Kelley, Ronald R. Johnson, Stephen G. Grant
Faculty Articles

Tobacco Smoke Exposure and Somatic Mutation in Newborns, Stephen G. Grant
Faculty Articles

Permanently Blocked Stem Cells Derived from Breast Cancer Cell Lines, Gangadharan B. Sajithlal, Kristi Rothermund, Fang Zhang, David J. Dabbs, Jean J. Latimer, Stephen G. Grant, Edward V. Prochownik
Faculty Articles

Melatonin and Breast Cancer: A Review of Clinical Studies, Cellular Mechanisms and Future Perspectives, Stephen G. Grant, Melanie A. Melan, Jean J. Latimer, Paula A. Witt-Enderby
Faculty Articles

(Z)-1,1-Dichloro-2-(4-methoxyphenyl)-3-phenylcyclopropane Induces Concentration-dependent Growth Inhibition, Apoptosis, and Coordinates Regulation of Apoptotic Genes in TRAMP Cells, Cathy A. Thomas, Stephen G. Grant, Beth R. Pflug, Robert H. Getzenberg, Billy W. Day
Faculty Articles

Cell-type-specific Level of DNA Nucleotide Excision Repair in Primary Human Mammary and Ovarian Epithelial Cell Cultures, Jean Johanna Latimer, Jennifer M. Johnson, Tiffany D. Miles, Jason M. Dimsdale, Robert P. Edwards, James L. Kelley, Stephen G. Grant
Faculty Articles

Elevated Levels of Somatic Mutation in a Manifesting BRCA1 Mutation Carrier, Stephen G. Grant, Rubina Das, Christine M. Cerceo, Wendy S. Rubinstein, Jean Johanna Latimer
Faculty Articles

Association between Biomarkers of Environmental Exposure and Increased Risk of Breast Cancer, Maryanne Donovan, Tiffany D. Miles, Jean Johanna Latimer, Stephen G. Grant, Evelyn Talbott, Annie J. Sasco, Devra L. Davis
Faculty Articles

Prospective Screening Study of 0.5 Tesla Dedicated Magnetic Resonance Imaging for the Detection of Breast Cancer in Young, High Risk Women, Wendy S. Rubinstein, Jean Johanna Latimer, Jules H. Sumkin, Michelle Huerbin, Stephen G. Grant, Victor G. Vogel
Faculty Articles

Qualitatively and Quantitatively Similar Effects of Active and Passive Maternal Tobacco Smoke Exposure on in Utero Mutagenesis at the HPRT Locus, Stephen G. Grant
Faculty Articles

Haploinsufficiency for BRCA1 is Associated with Normal Levels of DNA Nucleotide Excision Repair in Breast Tissue and Blood Lymphocytes, Jean Johanna Latimer, Wendy S. Rubinstein, Jennifer M. Johnson, Amal Kanbour-Shakir, Victor G. Vogel, Stephen G. Grant
Faculty Articles

Unusual Pattern of Bone Marrow Somatic Mutation in Pediatric Patients Referred for Cytogenetic Analysis, Stephen G. Grant, Reagan K. McLoughlin, Sharon L. Wenger
Faculty Articles

The GPA in Vivo Somatic Mutation Assay, Stephen G. Grant
Faculty Articles

HPRT Gene Alterations in Umbilical Cord Blood T-lymphocytes in Newborns of Mothers Exposed to Tobacco Smoke during Pregnancy, Phouthone Keohavong, Liqiang Xi, Richard D. Day, Lifang Zhang, Stephen G. Grant, Billy W. Day, Roberta B. Ness, William L. Bigbee
Faculty Articles

Use of the Glycophorin A Bone Marrow Somatic Mutation Assay for Rapid, Unambiguous Identification of Fanconi anemia Homozygotes Regardless of GPA Genotype, Viktoria N. Evdokimova, Reagan K. McLoughlin, Sharon L. Wenger, Stephen G. Grant
Faculty Articles

Comparison of Established Cell Lines at Different Passages by Karyotype and Comparative Genomic Hybridization, Sharon L. Wenger, Jamie R. Senft, Linda M. Sargent, Narendra Bairwa, Stephen G. Grant
Faculty Articles

Unique Tissue-specific Level of DNA Nucleotide Excision Repair in Primary Human Mammary Epithelial Cultures, Stephen G. Grant, Jean Johanna Latimer, Tariq Nazir, Lisa C. Flowers, Michael J. Forlenza, Kelly Beaudry-Rodgers
Faculty Articles

Mutational Spectrum of N-hydroxy-N-acetyl-4-aminobiphenyl at Exon 3 of the HPRT Gene, Beatriz Zayas-Rivera, Lifang Zhang, Stephen G. Grant, Phouthone Keohavong, Billy W. Day
Faculty Articles

A Mathematical Model of in Vitro Cancer Cell Growth and Treatment with the Antimitotic Agent Curacin A, Frank Kozusko, Pao-Hsiu Chen, Stephen G. Grant, Billy W. Day, John C. Panetta
Faculty Articles

Physicochemical and Graph Theoretical Descriptors in Developmental Toxicity SAR: A Comparative Study, Orest T. Macina, Nancy B. Sussman, H Gregg Claycamp, Stephen G. Grant
Faculty Articles

Molecular Epidemiology of Human Cancer: Biomarkers of Genotoxic Exposure and Susceptibility, Stephen G. Grant
Faculty Articles

Z-1,1-Dichloro-2,3-diphenylcyclopropanes Block Human Prostate Carcinoma Cell Proliferation, Inhibit Prostate-specific Antigen Expression, and Initiate Apoptosis, Raghavan Balachandran, Stephen G. Grant, Manda J. Welsh, Billy W. Day
Faculty Articles

Analysis of Genomic Instability using Multiple Assays in a Patient with Rothmund-Thomson Syndrome, Stephen G. Grant, Sharon L. Wenger, Jean Johanna Latimer, Darcy Thull, L W. Burke
Faculty Articles

Genetic Instability and Hematologic Disease Risk in Werner Syndrome Patients and Heterozygotes, Michael J. Moser, William L. Bigbee, Stephen G. Grant, Mary J. Emond, Richard G. Langlois, Ronald H. Jensen, Junko Oshima, Raymond J. Monnat, Jr
Faculty Articles

Modeling the Mouse Lymphoma Forward Mutational Assay: The Gene-Tox Program Database, Stephen G. Grant, Ying Ping Zhang, Gilles Klopman, Herbert S. Rosenkranz
Faculty Articles

Impact of Maternal Lifestyle Factors on Newborn HPRT Mutant Frequencies and Molecular Spectrum—Initial Results from the Prenatal Exposures and Preeclampsia Prevention (PEPP) Study, William L. Bigbee, Richard D. Day, Stephen G. Grant, Phouthone Keohavong, Liqiang Xi, Lifang Zhang, Roberta B. Ness
Faculty Articles

Myeloperoxidase-catalyzed Redox-cycling of Phenol Promotes Lipid Peroxidation and Thiol Oxidation in HL-60 Cells, Radolav Goldman, H Gregg Claycamp, Michael A. Sweetland, Andrew V. Sedlov, Vladimir A. Tyurin, Elena R. Kisin, Yulia Y. Tyurina, Vladimir B. Ritov, Sharon L. Wenger, Stephen G. Grant, Valerian E. Kagan
Faculty Articles

Induction of Human Breast Cancer Cell Apoptosis from G2/M Preceded by Stimulation into the Cell Cycle by Z-1,1-dichloro-2,3-diphenylcyclopropane, Raghavan Balachandran, Ernst ter Haar, Jack C. Yalowich, Manda J. Welsh, Stephen G. Grant, Billy W. Day
Faculty Articles

Development, Characterization and Application of Predictive-toxicology Models, Herbert S. Rosenkranz, Albert R. Cunningham, Ying Ping Zhang, H Gregg Claycamp, Orest T. Macina, Nancy B. Sussman, Stephen G. Grant, Gilles Klopman
Faculty Articles

Diagnosis of Ataxia Telangiectasia with the Glycophorin A Somatic Mutation Assay, Stephen G. Grant, Wendy Reeger, S L. Wenger
Faculty Articles

Increased Sensitivity of the Antiestrogen-resistant MCF7/LY2 Human Breast Carcinoma Cell Line to Apoptosis Induced by the Novel Microtubule-stabilizing Agent (+)-Discodermolide, Raghavan Balachandran, Stephen G. Grant, Manda J. Welsh, Billy W. Day
Faculty Articles

Induction of Forward Mutations at the Thymidine Kinase Locus of Mouse Lymphoma Cells: Evidence for Electrophilic and Non-electrophilic Mechanisms, Barbara Henry, Stephen G. Grant, Gilles Klopman, Herbert S. Rosenkranz
Faculty Articles

Human in Vivo Somatic Mutation Measured at Two Loci: Individuals with Stably Elevated Background Erythrocyte Glycophorin A (gpa) Variant Frequencies Exhibit Normal T-lymphocyte hprt Mutant Frequencies, William L. Bigbee, James C. Fuscoe, Stephen G. Grant, Irene M. Jones, Ann E. Gorvad, Karen Harrington-Brock, Cheryl L. Strout, Cynthia B. Thomas, Martha M. Moore
Faculty Articles

The Potent Microtubule-stabilizing Agent (+)-Discodermolide Induces Apoptosis in Human Breast Carcinoma Cells—Preliminary Comparisons to Paclitaxel, Raghavan Balachandran, Ernst ter Haar, Manda J. Welsh, Stephen G. Grant, Billy W. Day
Faculty Articles

Radiobiological Evaluation of Immigrants from the Vicinity of Chernobyl, Gordon K. Livingston, Ronald H. Jensen, Edward B. Silberstein, Jerry D. Hinnefeld, Gary Pratt, William L. Bigbee, Richard G. Langlois, Stephen G. Grant, Rakesh Shukla
Faculty Articles

Glycophorin A as a Biological Dosimeter for Radiation Dose to the Bone Marrow from Iodine-131, Ronald H. Jensen, James C. Reynolds, Jacob Robbins, William L. Bigbee, Stephen G. Grant, Richard G. Langlois, J Desiree Pineda, Taisheng Lee, W Craig Barker
Faculty Articles

Structural and Mechanistic Bases for the Induction of Mitotic Chromosomal Loss and Duplication ('Malsegregation') in the Yeast Saccharomyces cerevisiae: Relevance to Human Carcinogenesis and Developmental Toxicology, Mei Liu, Stephen G. Grant, Orest T. Macina, Gilles Klopman, Herbert S. Rosenkranz
Faculty Articles

SfaNI Polymorphism Distinguishes the Alleles of the Glycophorin A Locus that Determine the MN Blood Group, Sharon H. Leos, William L. Bighee, Ronald H. Jensen, Stephen G. Grant
Faculty Articles

Glycophorin A Somatic Cell Mutation Frequencies in Finnish Reinforced Plastics Workers Exposed to Styrene, William L. Bigbee, Stephen G. Grant, Richard G. Langlois, Ronald H. Jensen, Ahti Anttila, Pirkko Pfäffli, Kaija Pekari, Hannu Norppa
Faculty Articles

Sensitivity of Somatic Mutations in Human Umbilical Cord Blood to Maternal Environments, David K. Manchester, Janice A. Nicklas, J Patrick O'Neill, Malcolm J. Lippert, Stephen G. Grant, Richard G. Langlois, Dan H. Moore, 3rd, Ronald H. Jensen, Richard J. Albertini, William L. Bigbee
Faculty Articles

Elevated Frequency of Glycophorin A Mutations in Erythrocytes from Chernobyl Accident Victims, Ronald H. Jensen, Richard G. Langlois, William L. Bigbee, Stephen G. Grant, Dan Moore, 2nd, Maria Pilinskaya, Irena Vorobtsova, Pavel Pleshanov
Faculty Articles

Molecular Characterization of Glycophorin A Transcripts in Human Erythroid Cells using RT-PCR, Allele-specific Restriction, and Sequencing, B R. DuPont, Stephen G. Grant, Sharon H. Oto, William L. Bigbee, Ronald H. Jensen, Richard G. Langlois
Faculty Articles

Use of Allele-specific Glycophorin A Antibodies to Enumerate Fetal Erythroid Cells in Maternal Circulation, William L. Bigbee, Stephen G. Grant
Faculty Articles

Bone Marrow Somatic Mutation after Genotoxic Cancer Therapy, Stephen G. Grant, William L. Bigbee
Faculty Articles

Analysis of Somatic Cell Mutations at the Glycophorin A Locus in Atomic Bomb Survivors: A Comparative Study of Assay Methods, Richard G. Langlois, Mitoshi Akiyama, Yoichiro Kusunoki, Barbara R. DuPont, Dan H. Moore, 2nd, William L. Bigbee, Stephen G. Grant, Ronald H. Jensen
Faculty Articles

In vivo Somatic Mutation and Segregation at the Human Glycophorin A (GPA) Locus: Phenotypic Variation Encompassing both Gene-specific and Chromosomal Mechanisms, Stephen G. Grant, William L. Bigbee
Faculty Articles

Flow Cytometric Isolation of Differentiated Cell-types from Embryoid Bodies, Roger A. Pedersen, Stephen G. Grant, Carol A. Burdsal, Jean Johanna Latimer
Faculty Articles

Use of the Glycophorin A Human Mutation Assay to Study Workers Exposed to Styrene, Penelope J. Compton-Quintana, Ronald H. Jensen, William L. Bigbee, Stephen G. Grant, Richard G. Langlois, Martyn T. Smith, Stephen M. Rappaport
Faculty Articles

Allele Loss at the Human GPA Locus: A Model for Recessive Oncogenesis with Potential Clinical Application, Stephen G. Grant, William L. Bigbee, Richard G. Langlois, Ronald H. Jensen
Faculty Articles

Laser-based Flow Cytometric Analysis of Genotoxicity of Humans Exposed to Ionizing Radiation during the Chernobyl accident, Ronald H. Jensen, William L. Bigbee, Richard G. Langlois, Stephen G. Grant, Pavel G. Pleshanov, Andre A. Chirkov, Maria A. Pilinskaya
Faculty Articles

Detailed Genetic Mapping of the A-raf Proto-oncogene on the Mouse X Chromosome, Stephen G. Grant, Verne M. Chapman
Faculty Articles

Characterization of a Murine cDNA Encoding a Member of the Carboxylesterase Multigene Family, Mariana Ovnic, Katherine Tepperman, Sukumar Medda, Rosemary W. Elliott, Dennis A. Stephenson, Stephen G. Grant, Roger E. Ganschow
Faculty Articles

Somatic Cell Genotoxicity at the Glycophorin A Locus in Humans, Ronald H. Jensen, Stephen G. Grant, Richard G. Langlois, William L. Bigbee
Faculty Articles

Mechanisms of X-chromosome Regulation, Stephen G. Grant, Verne M. Chapman
Faculty Articles

Identification of an X-linked Member of the Odc Gene Family in the Mouse, Dennis A. Stephenson, Rosemary W. Elliott, Verne M. Chapman, Stephen G. Grant
Faculty Articles

X-chromosome Gene Order in Different Mus Species Crosses, Dennis A. Stephenson, Stephen G. Grant, Linda J. Mullins, Amy E. Scolese, Amanda J. O'Reilly, Verne M. Chapman
Faculty Articles

X-chromosome Linked Mutations Affecting Mosaic Expression of the Mouse X Chromosome, Verne M. Chapman, Stephen G. Grant, Rebecca A. Benz, Darla R. Miller, Dennis A. Stephenson
Faculty Articles

The Effect of Lactamide on the Mutant eyeless-2, Stephen G. Grant
Faculty Articles