A Mutation in LTBP2 Causes Congenital Glaucoma in Domestic Cats (Felis catus), Markus H. Kuehn, Koren A. Lipsett, Marilyn Menotti-Raymond, S. Scott Whitmore, Todd E. Scheetz, Victor A. David, Stephen J. O'Brien, Zhongyuan Zhao, Jackie K. Jens, Elizabeth M. Snella, N. Matthew Ellinwood, Gillian J. McLellan
Stephen O'Brien

Signal Localization: A New Approach in Signal Discovery, Sergey Malov, Alexey Antonik, Minzhong Tang, Alexandre Berred, Yi Zeng, Stephen J. O'Brien
Stephen O'Brien

On Survival Categorical Methods Based on an Extended Actuarial Estimator, Sergey Malov, Stephen J. O'Brien
Stephen O'Brien

Signal Localization: A New Approach in Signal Discovery, Sergey Malov, Alexey Antonik, Minzhong Tang, Alexandre Berred, Yi Zeng, Stephen J. O'Brien
Biology Faculty Articles

A Genome-To-Genome Analysis of Associations between Human Genetic Variation, HIV-1 Sequence Diversity, and Viral Control, Istvan Bartha, Jonathan M. Carlson, Chanson J. Brumme, Paul J. McLaren, Zabrina L. Brumme, Mina John, David W. Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio Lopez-Galindez, Concepcion Casado, Andri Rauch, Huldrych F. Gunthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J. O'Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltan Kutalik, Todd M. Allen, Viktor Muller, P. Richard Harrigan, David Heckerman, Amalio Telenti, Jacques Fellay
Stephen O'Brien

A Novel Form of Human Polymorphism Involving the hDHFR-ψ1 Pseudogene Identifies Three RFLPs, Nicholas P. Anagnou, S. E. Antonarakis, Stephen J. O'Brien, Arthur W. Nienhuis
Stephen O'Brien

A Population-Based Study to Investigate Host Genetic Factors Associated with Hepatitis B Infection and Pathogenesis in the Chinese Population, Zheng Zheng, Li Guan, Ping An, Shan Sun, Stephen J. O'Brien, Cheryl Winkler
Stephen O'Brien

Accounting for Multiple Comparisons in a Genome-Wide Association Study (GWAS), Randall C. Johnson, George W. Nelson, Jennifer L. Troyer, J. A. Lautenberger, Bailey Kessing, Cheryl Winkler, Stephen J. O'Brien
Stephen O'Brien

APOBEC3G Genetic Variants and Their Influence on the Progression to AIDS, Ping An, Gabriela Bleiber, Priya Duggal, George Nelson, Margaret May, Bastien Mangeat, Irene Alobwede, Didier Trono, David Vlahov, Sharyne Donfield, James J. Goedert, John Phair, Susan Buchbinder, Stephen J. O'Brien, Amalio Telenti, Cheryl Winkler
Stephen O'Brien

An ∼140-kb Deletion Associated with Feline Spinal Muscular Atrophy Implies an Essential LIX1 Function for Motor Neuron Survival, John C. Fyfe, Marilyn Menotti-Raymond, Victor A. David, Lars Brichta, Alejandro A. Schaffer, R. Agarwala, William J. Murphy, William J. Wedemeyer, Brittany L. Gregory, Bethany G. Buzzell, Meghan C. Drummond, Brunhilde Wirth, Stephen J. O'Brien
Stephen O'Brien

Association of DC-SIGN Promoter Polymorphism with Increased Risk for Parenteral, but Not Mucosal, Acquisition of Human Immunodeficiency Virus Type 1 Infection, Maureen P. Martin, Michael M. Lederman, Holli B. Hutcheson, James J. Goedert, George W. Nelson, Yvette van Kooyk, Roger Detels, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington
Stephen O'Brien

Chromosomal Localization of Nucleic Acid-Binding Proteins by Affinity Mapping: Assignment of the IRE-Binding Protein Gene to Human Chromosome 9, Matthias W. Hentze, Hector Seuanez, Stephen J. O'Brien, Joe B. Harford, Richard D. Klausner
Stephen O'Brien

Common Genetic Variation and the Control of HIV-1 in Humans, Jacques Fellay, Dongliang Ge, Kevin V. Shianna, Sara Colombo, Bruno Ledergerber, Elizabeth T. Cirulli, Thomas J. Urban, Kunlin Zhang, Curtis Gumbs, Jason P. Smith, Antonella Castagna, Alessandro Cozzi-Lepri, Andrea de Luca, Philippa Easterbrook, Huldrych F. Gunthard, Simon Mallal, Cristina Mussini, Judith Dalmau, Javier Martinez-Picado, Jose M. Miro, Niels Obel, Steven M. Wolinsky, Jeremy J. Martinson, Roger Detels, Joseph Margolick, Lisa Jacobson, Patrick Descombes, Stylianos E. Antonarakis, Jacques S. Beckmann, Stephen J. O'Brien, Norman L. Letvin, Andrew J. McMichael, Barton F. Haynes, Mary Carrington, Sheng Feng, Amalio Telenti, David B. Goldstein
Stephen O'Brien

Consistent Effects of TSG101 Genetic Variability on Multiple Outcomes of Exposure to Human Immunodeficiency Virus Type 1, Arman A. Bashirova, Gabriela Bleiber, Ying Qi, Holli Hutcheson, Traci Yamashita, Randall C. Johnson, Jie Cheng, Galit Alter, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Margaret May, Frank Maldarelli, Lisa Jacobson, Stephen J. O'Brien, Amalio Telenti, Mary Carrington
Stephen O'Brien

Effect of a Single Amino Acid Change in MHC Class I Molecules on the Rate of Progression to AIDS, Xiaojiang Gao, George W. Nelson, Peter Karacki, Maureen P. Martin, John Phair, Richard A. Kaslow, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington
Stephen O'Brien

Emerging Viruses in the Felidae: Shifting Paradigms, Stephen J. O'Brien, Jennifer L. Troyer, Meredith Brown, Warren E. Johnson, Agostinho Antunes, Melody E. Roelke, Jill Pecon-Slattery
Stephen O'Brien

Evaluation and Integration of Genetic Signature for Prediction Risk of Nasopharyngeal Carcinoma in Southern China, Xiuchan Guo, Cheryl Winkler, Ji Li, Li Guan, Minzhong Tang, Jian Liao, Hong Deng, Guy de The, Yi Zeng, Stephen J. O'Brien
Stephen O'Brien

Evolution of a Major Drug Metabolizing Enzyme Defect in the Domestic Cat and Other Felidae: Phylogenetic Timing and the Role of Hypercarnivory, Binu Shrestha, J. Michael Reed, Philip T. Starks, Gretchen E. Kaufman, Jared V. Goldstone, Melody E. Roelke, Stephen J. O'Brien, Klaus-Peter Koepfli, Laurence Frank, Michael H. Court
Stephen O'Brien

Extensive Conservation of Sex Chromosome Organization Between Cat and Human Revealed by Parallel Radiation Hybrid Mapping, William J. Murphy, Shan Sun, Zhang-Qun Chen, Jill Pecon-Slattery, Stephen J. O'Brien
Stephen O'Brien

GWATCH: A Web Platform for Automated Gene Association Discovery Analysis, Anton Svitin, Sergey Malov, Nikolay Cherkasov, Paul Geerts, Mikhail Rotkevich, Pavel Dobrynin, Andrey Shevchenko, Li Guan, Jennifer L. Troyer, Sher L. Hendrickson, Holli Hutcheson Dilks, T. K. Oleksyk, Sharyne Donfield, Edward Gomperts, Douglas A. Jabs, Efe Sezgin, Mark Van Natta, P. Richard Harrigan, Zabrina L. Brumme, Stephen J. O'Brien
Stephen O'Brien

Genetic Factors Leading to Chronic Epstein–Barr Virus Infection and Nasopharyngeal Carcinoma in South East China: Study Design, Methods and Feasibility, Xiu Chan Guo, Kevin Scott, Yan Liu, Michael Dean, Victor David, George W. Nelson, Randall C. Johnson, Holli H. Dilks, J. A. Lautenberger, Bailey Kessing, Janice S. Martenson, Li Guan, Shan Sun, Hong Deng, Yuming Zheng, Guy de The, Jian Liao, Yi Zeng, Stephen J. O'Brien, Cheryl Winkler
Stephen O'Brien

Genetic Characterization of Feline Leukemia Virus from Florida Panthers, Meredith Brown, Mark W. Cunningham, Alfred L. Roca, Jennifer L. Troyer, Warren E. Johnson, Stephen J. O'Brien
Stephen O'Brien

Genetic Characterization of Human c-rel Sequences, Elise Brownell, Stephen J. O'Brien, William Nash, Nancy Rice
Stephen O'Brien

Genetic Polymorphisms of CYP2E1, GSTP1, NQO1 and MPO and the Risk of Nasopharyngeal Carcinoma in a Han Chinese Population of Southern China, Xiuchan Guo, Yi Zeng, Hong Deng, Jian Liao, Yuming Zheng, Ji Li, Bailey Kessing, Stephen J. O'Brien
Stephen O'Brien

Genetic Protection against Hepatitis B Virus Conferred by CCR5Δ32: Evidence that CCR5 Contributes to Viral Persistence, Chloe L. Thio, Jacquie Astemborski, Arman A. Bashirova, Timothy L. Mosbruger, Spencer Greer, Mallory D. Witt, James J. Goedert, Margaret Hilgartner, Audrey Majesk, Stephen J. O'Brien, David L. Thomas, Mary Carrington
Stephen O'Brien

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression, Sher L. Hendrickson, J. A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Lawrence Kingsley, James J. Goedert, Gregory D. Kirk, Edward Gomperts, Susan Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien
Stephen O'Brien

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND), Sudha K. Iyengar, John R. Sedor, Barry I. Freedman, W. H. Linda Kao, Matthias Kretzler, Benjamin J. Keller, Hanna E. Abboud, Sharon G. Adler, Lyle G. Best, Donald W. Bowden, Allison Burlock, Yii-Der Ida Chen, Shelley A. Cole, Mary E. Comeau, Jeffrey M. Curtis, Jasmin DIvers, Christiane Drechsler, Ravi Duggirala, Robert C. Elston, Xiuqing Guo, Huateng Huang, Michael M. Hoffmann, Barbara V. Howard, Eli Ipp, Paul L. Kimmel, Michael J. Klag, William C. Knowler, Orly F. Kohn, Tennille S. Leak, David J. Leehey, Man Li, Alka Malhotra, Winfried Marz, Viji Nair, Robert G. Nelson, Susanne B. Nicholas, Stephen J. O'Brien, Madeleine V. Pahl, Rulan S. Parekh, Marcus G. Pezzolesi, Rebekah S. Rasooly, Charles N. Rotimi, Jerome I. Rotter, Jeffrey R. Schelling, Michael F. Seldin, Vallabh O. Shah, Adam M. Smiles, Michael W. Smith, Kent D. Taylor, Farook Thameem, Denyse P. Thornley-Brown, Barbara J. Truitt, Christoph Wanner, E. Jennifer Weil, Cheryl Winkler, Philip G. Zager, Robert P. Igo Jr., Robert L. Hanson, Carl D. Langefeld
Stephen O'Brien

Genome-Wide and Differential Proteomic Analysis of Hepatitis B Virus and Aflatoxin B1 Related Hepatocellular Carcinoma in Guangxi, China, Lu-Nan Qi, Le-Qun Qi, Yuan-Yuan Chen, Zhao-Hong Chen, Tao Bai, Bang-De Xiang, Xiao Qin, Kai-Yin Xiao, Min-Hao Peng, Zhi-Ming Liu, Tang-Wei Liu, Xue Qin, Shan Li, Ze-Guang Han, Zeng-Nan Mo, Regina M. Santella, Cheryl Winkler, Stephen J. O'Brien, Tao Peng
Stephen O'Brien

Genomic Organization, Sequence Divergence, and Recombination of Feline Immunodeficiency Virus from Lions in the Wild, Jill Pecon-Slattery, Carrie L. McCracken, Jennifer L. Troyer, Sue VandeWoude, Melody E. Roelke, Kerry Sondgeroth, Christiaan Winterbach, Stephen J. O'Brien
Stephen O'Brien

Genomically Intact Endogenous Feline Leukemia Viruses of Recent Origin, Alfred L. Roca, Jill Pecon-Slattery, Stephen J. O'Brien
Stephen O'Brien

HLA-Cw*04 and Hepatitis C Virus Persistence, Chloe L. Thio, Xiaojiang Gao, James J. Goedert, David Vlahov, Kenrad E. Nelson, Margaret Hilgartner, Stephen J. O'Brien, Peter Karacki, Jacquie Astemborski, Mary Carrington, David L. Thomas
Stephen O'Brien

Host Genomic Influences on HIV/AIDS, Stephen J. O'Brien, Sher L. Hendrickson
Stephen O'Brien

Identifying Selected Regions from Heterozygosity and Divergence Using a Light-Coverage Genomic Dataset from Two Human Populations, T. K. Oleksyk, Kai Zhao, Francisco M. De La Vega, Dennis A. Gilbert, Stephen J. O'Brien, Michael W. Smith
Stephen O'Brien

Insertional Polymorphisms of Endogenous Feline Leukemia Viruses, Alfred L. Roca, William G. Nash, Joan C. Menninger, William J. Murphy, Stephen J. O'Brien
Stephen O'Brien

Influence of the CCR2-V64I Polymorphism on Human Immunodeficiency Virus Type 1 Coreceptor Activity and on Chemokine Receptor Function of CCR2b, CCR3, CCR5, and CXCR4, Benhur Lee, Benjamin J. Doranz, Shalini Rana, Yanji Yi, Mario Mellado, Jose M. R. Frade, Carlos Martinez-A., Stephen J. O'Brien, Michael Dean, Ronald G. Collman, Robert W. Doms
Stephen O'Brien

MHC Class I Molecules and Progression to AIDS, Mary Carrington, Xiaojiang Gao, Stephen J. O'Brien
Stephen O'Brien

KIR/HLA Pleiotropism: Protection against Both HIV and Opportunistic Infections, Ying Qi, Maureen P. Martin, Xiaojiang Gao, Lisa Jacobson, James J. Goedert, Susan Buchbinder, Gregory D. Kirk, Stephen J. O'Brien, John Trowsdale, Mary Carrington
Stephen O'Brien

Mannose Binding Lectin Genotypes Influence Recovery from Hepatitis B Virus Infection, Chloe L. Thio, Timothy L. Mosbruger, Jacquie Astemborski, Spencer Greer, Gregory D. Kirk, Stephen J. O'Brien, David L. Thomas
Stephen O'Brien

Phylogenetic Associations of Human and Simian T-Cell Leukemia/Lymphotropic Virus Type I Strains: Evidence for Interspecies Transmission, Igor J. Koralnik, Enzo Boeri, W. Carl Saxinger, Anita Lo Monico, Jake Fullen, Antoine Gessain, Hong-Guang Guo, Robert C. Gallo, Phillip Markham, Vaniambadi Kalyanaraman, Vanessa Hirsch, Jonathan Allan, Krishna Murthy, Patricia Alford, Jill Pecon-Slattery, Stephen J. O'Brien, Genoveffa Ranchini
Stephen O'Brien

Polymorphisms of CUL5 are Associated with CD4+ T Cell Loss in HIV-1 Infected Individuals, Ping An, Priya Duggal, Li Hua Wang, Stephen J. O'Brien, Sharyne Donfield, James J. Goedert, John Phair, Susan Buchbinder, Gregory D. Kirk, Cheryl Winkler
Stephen O'Brien

Prevalence of Antibodies to Feline Parvovirus, Calicivirus, Herpesvirus, Coronavirus, and Immunodeficiency Virus and of Feline Leukemia Virus Antigen and the Interrelationship of These Viral Infections in Free-Ranging Lions in East Africa, Regina Hofmann-Lehmann, Daniela Fehr, Markus Grob, Muhamed Elgizoli, Craig Packer, Janice S. Martenson, Stephen J. O'Brien, Hans Lutz
Stephen O'Brien

Regulatory Polymorphisms in the Cyclophilin A Gene, PPIA, Accelerate Progression to AIDS, Ping An, Li Hua Wang, Holli Hutcheson-Dilks, George Nelson, Sharyne Donfield, James J. Goedert, Charles Rinaldo, Susan Buchbinder, Gregory D. Kirk, Stephen J. O'Brien, Cheryl Winkler
Stephen O'Brien

Reconstructing the Genomic Architecture of Mammalian Ancestors Using Multispecies Comparative Maps, William J. Murphy, Guillaume Bourque, Glenn Tesler, Pavel Pevzner, Stephen J. O'Brien
Stephen O'Brien

Role of Exonic Variation in Chemokine Receptor Genes on AIDS: CCRL2 F167Y Association with Pneumocystis Pneumonia, Ping An, Rongling Li, Ji Ming Wang, Teizo Yoshimura, Munehisa Takahashi, Ram Samudralal, Stephen J. O'Brien, John Phair, James J. Goedert, Gregory D. Kirk, Jennifer L. Troyer, Efe Sezgin, Susan Buchbinder, Sharyne Donfield, George W. Nelson, Cheryl Winkler
Stephen O'Brien

Significant Admixture Linkage Disequilibrium Across 30 cM Around the FY Locus in African Americans, J. A. Lautenberger, J. Claiborne Stephens, Stephen J. O'Brien, Michael W. Smith
Stephen O'Brien

The Case for Selection at CCR5-Δ32, Pardis Sabeti, Emily C. Walsh, Stephen F. Schaffner, Patrick Varilly, Ben Fry, Holli Hutcheson, Mike Cullen, Tarjei S. Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen J. O'Brien, Eric S. Lander
Stephen O'Brien

The Genome Russia Project: Closing the Largest Remaining Omission on the World Genome Map, T. K. Oleksyk, Vladimir Brukhin, Stephen J. O'Brien
Stephen O'Brien

The GLI-Kruppel Family of Human Genes, John M. Ruppert, Kenneth W. Kinzler, Albert J. Wong, Sandra H. Bigner, Fa-Ten Kao, Martha L. Law, Hector Seuanez, Stephen J. O'Brien, Bert Vogelstein
Stephen O'Brien

The Linkage Disequilibrium Maps of Three Human Chromosomes Across Four Populations Reflect Their Demographic History and a Common Underlying Recombination Pattern, Francisco M. De La Vega, Hadar Isaac, Andrew Collins, Charles R. Scafe, Bjarni V. Halldorsson, Xiaoping Su, Ross A. Lippert, Yu Wang, Marion Laig-Webster, Ryan T. Koehler, Janet S. Ziegle, Lewis T. Wogan, Junko F. Stevens, Kyle M. Leinen, Sheri J. Olson, Karl J. Guegler, Xiaoqing You, Lily H. Xu, Heinz G. Hemken, Francis Kalush, Mitsuo Itakura, Yi Zheng, Guy de The, Stephen J. O'Brien, Andrew G. Clark, Sorin Istrail, Michael W. Hunkapiller, Eugene G. Spier, Dennis A. Gilbert
Stephen O'Brien

The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition Groove, Minzhong Tang, J. A. Lautenberger, Xiaojiang Gao, Efe Sezgin, Sher L. Hendrickson, Jennifer L. Troyer, Victor A. David, Li Guan, Carl McIntosh, Xiuchan Guo, Yuming Zheng, Jian Liao, Hong Deng, Michael Malasky, Bailey Kessing, Cheryl Winkler, Mary Carrington, Guy de The, Yi Zeng, Stephen J. O'Brien
Stephen O'Brien

The t(11;14)(p15;q11) in a T-Cell Acute Lymphoblastic Leukemia Cell Line Activates Multiple Transcripts, Including Ttg-1, a Gene Encoding a Potential Zinc Finger Protein, Elizabeth A. McGuire, Richard D. Hockett, Karen M. Pollock, Marty F. Bartholdi, Stephen J. O'Brien, Stanley J. Korsmeyer
Stephen O'Brien

Tissue Sampling Methods and Standards for Vertebrate Genomics, Pamela B. Y. Wong, Edward O. Wiley, Warren E. Johnson, Oliver A. Ryder, Stephen J. O'Brien, David Haussler, Klaus-Peter Koepfli, Marlys L. Houck, Polina L. Perelman, Gabriela Mastromonaco, Andrew C. Bentley, Byrappa Venkatesh, Ya-ping Zhang, Robert W. Murphy
Stephen O'Brien

The κ-Deleting Element: Germline and Rearranged, Duplicated and Dispersed Forms, Winfried B. Graninger, Paula L. Goldman, Cynthia C. Morton, Stephen J. O'Brien, Stanley J. Korsmeyer
Stephen O'Brien

Unusual Polymorphisms in Human Immunodeficiency Virus Type 1 Associated with Nonprogressive Infection, Louis Alexander, Emma Weiskopf, Thomas C. Greenough, Nathan C. Gaddis, Marcy C. Auerbach, MIchael H. Malim, Stephen J. O'Brien, Bruce D. Walker, John L. Sullivan, Ronald C. Desrosiers
Stephen O'Brien

A Mutation in LTBP2 Causes Congenital Glaucoma in Domestic Cats (Felis catus), Markus H. Kuehn, Koren A. Lipsett, Marilyn Menotti-Raymond, S. Scott Whitmore, Todd E. Scheetz, Victor A. David, Stephen J. O'Brien, Zhongyuan Zhao, Jackie K. Jens, Elizabeth M. Snella, N. Matthew Ellinwood, Gillian J. McLellan
Biology Faculty Articles

Effect of Carcinoembryonic Antigen Production by Colorectal Cancer Cells on Tumor Microenvironment and Cancer Progression, Olga Bajenova, I. Evsyukov, Stephen J. O'Brien
Biology Faculty Articles

Putting Russia on the Genome Map, T. K. Oleksyk, Vladimir Brukhin, Stephen J. O'Brien
Biology Faculty Articles

The Genome Russia Project: Closing the Largest Remaining Omission on the World Genome Map, T. K. Oleksyk, Vladimir Brukhin, Stephen J. O'Brien
Biology Faculty Articles

On Survival Categorical Methods Based on an Extended Actuarial Estimator, Sergey Malov, Stephen J. O'Brien
Biology Faculty Proceedings, Presentations, Speeches, Lectures

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND), Sudha K. Iyengar, John R. Sedor, Barry I. Freedman, W. H. Linda Kao, Matthias Kretzler, Benjamin J. Keller, Hanna E. Abboud, Sharon G. Adler, Lyle G. Best, Donald W. Bowden, Allison Burlock, Yii-Der Ida Chen, Shelley A. Cole, Mary E. Comeau, Jeffrey M. Curtis, Jasmin DIvers, Christiane Drechsler, Ravi Duggirala, Robert C. Elston, Xiuqing Guo, Huateng Huang, Michael M. Hoffmann, Barbara V. Howard, Eli Ipp, Paul L. Kimmel, Michael J. Klag, William C. Knowler, Orly F. Kohn, Tennille S. Leak, David J. Leehey, Man Li, Alka Malhotra, Winfried Marz, Viji Nair, Robert G. Nelson, Susanne B. Nicholas, Stephen J. O'Brien, Madeleine V. Pahl, Rulan S. Parekh, Marcus G. Pezzolesi, Rebekah S. Rasooly, Charles N. Rotimi, Jerome I. Rotter, Jeffrey R. Schelling, Michael F. Seldin, Vallabh O. Shah, Adam M. Smiles, Michael W. Smith, Kent D. Taylor, Farook Thameem, Denyse P. Thornley-Brown, Barbara J. Truitt, Christoph Wanner, E. Jennifer Weil, Cheryl Winkler, Philip G. Zager, Robert P. Igo Jr., Robert L. Hanson, Carl D. Langefeld, Family Investigation of Nephropathy and Diabetes (FIND) Research Group
Biology Faculty Articles

GWATCH: A Web Platform for Automated Gene Association Discovery Analysis, Anton Svitin, Sergey Malov, Nikolay Cherkasov, Paul Geerts, Mikhail Rotkevich, Pavel Dobrynin, Andrey Shevchenko, Li Guan, Jennifer L. Troyer, Sher L. Hendrickson, Holli Hutcheson Dilks, T. K. Oleksyk, Sharyne Donfield, Edward Gomperts, Douglas A. Jabs, Efe Sezgin, Mark Van Natta, P. Richard Harrigan, Zabrina L. Brumme, Stephen J. O'Brien
Biology Faculty Articles

Genetic Factors Involved in Human Colorectal Cancer Metastasis, Olga Bajenova, Stephen J. O'Brien
Biology Faculty Articles

Carcinoembryonic Antigen Promotes Colorectal Cancer Progression by Targeting Adherens Junction Complexes, Olga Bajenova, Nina Chaika, Elena Tolkunova, Alexander Davydov-Sinitsyn, Svetlana Gapon, Peter Thomas, Stephen J. O'Brien
Biology Faculty Articles

Evaluation and Integration of Genetic Signature for Prediction Risk of Nasopharyngeal Carcinoma in Southern China, Xiuchan Guo, Cheryl Winkler, Ji Li, Li Guan, Minzhong Tang, Jian Liao, Hong Deng, Guy de The, Yi Zeng, Stephen J. O'Brien
Biology Faculty Articles

Genome-Wide and Differential Proteomic Analysis of Hepatitis B Virus and Aflatoxin B1 Related Hepatocellular Carcinoma in Guangxi, China, Lu-Nan Qi, Le-Qun Qi, Yuan-Yuan Chen, Zhao-Hong Chen, Tao Bai, Bang-De Xiang, Xiao Qin, Kai-Yin Xiao, Min-Hao Peng, Zhi-Ming Liu, Tang-Wei Liu, Xue Qin, Shan Li, Ze-Guang Han, Zeng-Nan Mo, Regina M. Santella, Cheryl Winkler, Stephen J. O'Brien, Tao Peng
Biology Faculty Articles

A Genome-To-Genome Analysis of Associations between Human Genetic Variation, HIV-1 Sequence Diversity, and Viral Control, Istvan Bartha, Jonathan M. Carlson, Chanson J. Brumme, Paul J. McLaren, Zabrina L. Brumme, Mina John, David W. Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio Lopez-Galindez, Concepcion Casado, Andri Rauch, Huldrych F. Gunthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J. O'Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltan Kutalik, Todd M. Allen, Viktor Muller, P. Richard Harrigan, David Heckerman, Amalio Telenti, Jacques Fellay
Biology Faculty Articles

Host Genomic Influences on HIV/AIDS, Stephen J. O'Brien, Sher L. Hendrickson
Biology Faculty Articles

The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition Groove, Minzhong Tang, J. A. Lautenberger, Xiaojiang Gao, Efe Sezgin, Sher L. Hendrickson, Jennifer L. Troyer, Victor A. David, Li Guan, Carl McIntosh, Xiuchan Guo, Yuming Zheng, Jian Liao, Hong Deng, Michael Malasky, Bailey Kessing, Cheryl Winkler, Mary Carrington, Guy de The, Yi Zeng, Stephen J. O'Brien
Biology Faculty Articles

Risk Factors for Symptomatic Hyperlactatemia and Lactic Acidosis Among Combination Antiretroviral Therapy-Treated Adults in Botswana: Results from a Clinical Trial, C. William Wester, Svetlana K. Eden, Bryan E. Shepherd, Herman Bussmann, Vladimir Novitsky, David C. Samuels, Sher L. Hendrickson, Cheryl Winkler, Stephen J. O'Brien, Max Essex, Richard T. D'Aquila, Victor deGruttola, Richard G. Marlink
Biology Faculty Articles

Multicohort Genomewide Association Study Reveals a New Signal of Protection Against HIV-1 Acquisition, Sophie Limou, Olivier Delaneau, Danielle van Manen, Ping An, Efe Sezgin, Sigrid Le Clerc, Cedric Coulonges, Jennifer L. Troyer, Jan H. Veldink, Leonard H. van den Berg, Jean-Louis Spadoni, Lieng Taing, Taoufik Labib, Matthieu Montes, Jean-Francois Delfraissy, Francois Schachter, Stephen J. O'Brien, Susan Buchbinder, Mark Van Natta, Douglas A. Jabs, Philippe Froguel, Hanneke Schuitemaker, Cheryl Winkler, Jean-Francois Zagury
Biology Faculty Articles

Genetic Association and Gene-Gene Interaction Analyses in African American Dialysis Patients With Nondiabetic Nephropathy, Meredith A. Bostrom, W. H. Linda Kao, Man Li, Hanna E. Abboud, Sharon G. Adler, Sudha K. Iyengar, Paul L. Kimmel, Robert L. Hanson, Susanne B. Nicholas, Rebekah S. Rasooly, John R. Sedor, Josef Coresh, Orly F. Kohn, David J. Leehey, Denyse Thornley-Brown, Erwin P. Bottinger, Michael S. Lipkowitz, Lucy A. Meoni, Michael J. Klag, Lingyi Lu, Pamela J. Hicks, Carl D. Langefeld, Rulan S. Parekh, Donald W. Bowden, Barry I. Freedman, Stephen J. O'Brien, Family Investigation of Nephropathy and Diabetes (FIND) Research Group
Biology Faculty Articles

Emerging Viruses in the Felidae: Shifting Paradigms, Stephen J. O'Brien, Jennifer L. Troyer, Meredith Brown, Warren E. Johnson, Agostinho Antunes, Melody E. Roelke, Jill Pecon-Slattery
Biology Faculty Articles

Tissue Sampling Methods and Standards for Vertebrate Genomics, Pamela B. Y. Wong, Edward O. Wiley, Warren E. Johnson, Oliver A. Ryder, Stephen J. O'Brien, David Haussler, Klaus-Peter Koepfli, Marlys L. Houck, Polina L. Perelman, Gabriela Mastromonaco, Andrew C. Bentley, Byrappa Venkatesh, Ya-ping Zhang, Robert W. Murphy, Genome 10K Project Community of Scientists
Biology Faculty Articles

FIV Diversity: FIVPle Subtype Composition May Influence Disease Outcome in African Lions, Jennifer L. Troyer, Melody E. Roelke, Jillian M. Jespersen, Natalie Baggett, Valerie A. Buckley-Beason, Dan MacNulty, Meggan Craft, Craig Packer, Jill Pecon-Slattery, Stephen J. O'Brien
Biology Faculty Articles

Role of Exonic Variation in Chemokine Receptor Genes on AIDS: CCRL2 F167Y Association with Pneumocystis Pneumonia, Ping An, Rongling Li, Ji Ming Wang, Teizo Yoshimura, Munehisa Takahashi, Ram Samudralal, Stephen J. O'Brien, John Phair, James J. Goedert, Gregory D. Kirk, Jennifer L. Troyer, Efe Sezgin, Susan Buchbinder, Sharyne Donfield, George W. Nelson, Cheryl Winkler
Biology Faculty Articles

Association of Host Genetic Risk Factors with the Course of Cytomegalovirus Retinitis in Patients Infected with Human Immunodeficiency Virus, Efe Sezgin, Mark Van Natta, Alka Ahuja, Alice Lyon, Sunil Srivastava, Jennifer L. Troyer, Stephen J. O'Brien, Douglas A. Jabs, Studies of the Ocular Complications of AIDS Research Group
Biology Faculty Articles

Genome-Wide Association Study Implicates PARD3B-Based AIDS Restriction, Jennifer L. Troyer, George W. Nelson, J. A. Lautenberger, Leslie Chinn, Carl McIntosh, Randall C. Johnson, Efe Sezgin, Bailey Kessing, Michael Malasky, Sher L. Hendrickson, Guan Li, J. U. Pontius, M. Tang, Ping An, Cheryl Winkler, Sophie Limou, Sigrid le Clerc, Olivier Delaneau, Jean-Francois Zagury, Hanneke Schuitemaker, Danielle van Manen, Jay H. Bream, Edward Gomperts, Susan Buchbinder, James J. Goedert, Gregory Kirk, Stephen J. O'Brien
Biology Faculty Articles

A Common HLA–DPA1 Variant is a Major Determinant of Hepatitis B Virus Clearance in Han Chinese, Ping An, Cheryl Winkler, Li Guan, Stephen J. O'Brien, Zheng Zeng, HBV Study Consortium
Biology Faculty Articles

Evolution of a Major Drug Metabolizing Enzyme Defect in the Domestic Cat and Other Felidae: Phylogenetic Timing and the Role of Hypercarnivory, Binu Shrestha, J. Michael Reed, Philip T. Starks, Gretchen E. Kaufman, Jared V. Goldstone, Melody E. Roelke, Stephen J. O'Brien, Klaus-Peter Koepfli, Laurence Frank, Michael H. Court
Biology Faculty Articles

Strong Influence of Human Leukocyte Antigen (HLA)-DP Gene Variants on Development of Persistent Chronic Hepatitis B Virus Carriers in the Han Chinese Population, Xiuchan Guo, Yong Zhang, Ji Li, Jingchen Ma, Zuli Wei, Wenjie Tan, Stephen J. O'Brien
Biology Faculty Articles

Genetic Associations of Variants in Genes Encoding HIV-Dependency Factors Required for HIV-1 Infection, Leslie Chinn, M. Tang, Bailey Kessing, J. A. Lautenberger, Jennifer L. Troyer, Michael Malasky, Carl McIntosh, Gregory D. Kirk, Steven M. Wolinsky, Susan Buchbinder, Edward Gomperts, James J. Goedert, Stephen J. O'Brien
Biology Faculty Articles

Widespread Retinal Degenerative Disease Mutation (rdAc) Discovered among a Large Number of Popular Cat Breeds, Marilyn Menotti-Raymond, Victor A. David, Solveig M. Pflueger, Melody E. Roelke, J. S. Kehler, Stephen J. O'Brien, Kristina Narfstrom
Biology Faculty Articles

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression, Sher L. Hendrickson, J. A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Lawrence Kingsley, James J. Goedert, Gregory D. Kirk, Edward Gomperts, Susan Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien
Biology Faculty Articles

Examination of Disease-Based Selection, Demographic History and Population Structure in European Y-Chromosome Haplogroup I, Efe Sezgin, Alyssa Drosdak, Carl McIntosh, Bailey Kessing, J. A. Lautenberger, James J. Goedert, John Phair, Jennifer L. Troyer, Michael W. Smith, Stephen J. O'Brien
Biology Faculty Articles

Effect of Host Genetics on Incidence of HIV Neuroretinal Disorder in Patients with AIDS, Efe Sezgin, Sher L. Hendrickson, Douglas A. Jabs, Mark Van Natta, Richard A. Lewis, Jennifer L. Troyer, Stephen J. O'Brien, SOCA Research Group
Biology Faculty Articles

Effect of Host Genetics on the Development of Cytomegalovirus Retinitis in Patients with AIDS, Efe Sezgin, Douglas A. Jabs, Sher L. Hendrickson, Mark Van Natta, Alexander Zdanov, Richard A. Lewis, Michael W. Smith, Jennifer L. Troyer, Stephen J. O'Brien, SOCA Research Group
Biology Faculty Articles

Genetic Polymorphisms of CYP2E1, GSTP1, NQO1 and MPO and the Risk of Nasopharyngeal Carcinoma in a Han Chinese Population of Southern China, Xiuchan Guo, Yi Zeng, Hong Deng, Jian Liao, Yuming Zheng, Ji Li, Bailey Kessing, Stephen J. O'Brien
Biology Faculty Articles

Mutation Discovered in a Feline Model of Human Congenital Retinal Blinding Disease, Marilyn Menotti-Raymond, Koren Holland Deckman, Victor David, Jaimie Myrkalo, Stephen J. O'Brien, Kristina Narfstrom
Biology Faculty Articles

Haplotype-Dependent HLA Susceptibility to Nasopharyngeal Carcinoma in a Southern Chinese Population, M. Tang, Yi Zeng, A. Poisson, D. Marti, Li Guan, Yuming Zheng, Hong Deng, Jian Liao, Xiuchan Guo, S. Sun, G. Nelson, Guy de The, Cheryl Winkler, Stephen J. O'Brien, Mary Carrington, Xiaojiang Gao
Biology Faculty Articles

Mitochondrial Haplogroups Are Associated With Risk of Neuroretinal Disorder in HIV-Positive Patients, Sher L. Hendrickson, Douglas A. Jabs, Mark Van Natta, Richard Alan Lewis, Douglas C. Wallace, Stephen J. O'Brien
Biology Faculty Articles

Multistage Genomewide Association Study Identifies a Locus at 1q41 Associated with Rate of HIV-1 Disease Progression to Clinical AIDS, Joshua T. Herbeck, Geoffrey S. Gottlieb, Cheryl Winkler, George W. Nelson, Ping An, Brandon S. Maust, Kim G. Wong, Jennifer L. Troyer, James J. Goedert, Bailey Kessing, Roger Detels, Steven M. Wolinsky, Jeremy J. Martinson, Susan Buchbinder, Gregory D. Kirk, Lisa Jacobson, Joseph Margolick, Richard A. Kaslow, Stephen J. O'Brien, James I. Mullins
Biology Faculty Articles

Accounting for Multiple Comparisons in a Genome-Wide Association Study (GWAS), Randall C. Johnson, George W. Nelson, Jennifer L. Troyer, J. A. Lautenberger, Bailey Kessing, Cheryl Winkler, Stephen J. O'Brien
Biology Faculty Articles

Common Genetic Variation and the Control of HIV-1 in Humans, Jacques Fellay, Dongliang Ge, Kevin V. Shianna, Sara Colombo, Bruno Ledergerber, Elizabeth T. Cirulli, Thomas J. Urban, Kunlin Zhang, Curtis Gumbs, Jason P. Smith, Antonella Castagna, Alessandro Cozzi-Lepri, Andrea de Luca, Philippa Easterbrook, Huldrych F. Gunthard, Simon Mallal, Cristina Mussini, Judith Dalmau, Javier Martinez-Picado, Jose M. Miro, Niels Obel, Steven M. Wolinsky, Jeremy J. Martinson, Roger Detels, Joseph Margolick, Lisa Jacobson, Patrick Descombes, Stylianos E. Antonarakis, Jacques S. Beckmann, Stephen J. O'Brien, Norman L. Letvin, Andrew J. McMichael, Barton F. Haynes, Mary Carrington, Sheng Feng, Amalio Telenti, David B. Goldstein, NIAID Center for HIV/AIDS Vaccine Immunology (CHAVI)
Biology Faculty Articles

CCL3L1 and HIV/AIDS Susceptibility, Thomas J. Urban, Amy C. Weintrob, Jacques Fellay, Sara Colombo, Kevin V. Shianna, Curtis Gumbs, Margalida Rotger, Kimberly Pelak, Kristen K. Dang, Roger Detels, Jeremy J. Martinson, Stephen J. O'Brien, Norman L. Letvin, Andrew J. McMichael, Barton F. Haynes, Mary Carrington, Amalio Telenti, Nelson L. Michael, David B. Goldstein
Biology Faculty Articles

Retinal Degeneration in the Abyssinian and Somali Cat (rdAc): Correlation between Genotype and Phenotype and rdAc Allele Frequency in Two Continents, Kristina Narfstrom, Victor David, Oswald Jarret, Julia A. Beatty, Vanessa R. Barrs, David Wilkie, Stephen J. O'Brien, Marilyn Menotti-Raymond
Biology Faculty Articles

Pathological Manifestations of Feline Immunodeficiency Virus (FIV) Infection in Wild African Lions, Melody E. Roelke, Meredith Brown, Jennifer L. Troyer, Hanlie Winterbach, Christiaan Winterbach, Graham Hemson, Dahlem Smith, Randall C. Johnson, Jill Pecon-Slattery, Alfred L. Roca, Kathleen A. Alexander, Lin Klein, Paolo Martelli, Karthiyani Krishnasamy, Stephen J. O'Brien
Biology Faculty Articles

Mitochondrial DNA Haplogroups Influence Lipoatrophy After Highly Active Antiretroviral Therapy, Sher L. Hendrickson, Lawrence Kingsley, Eduardo Ruiz-Pesini, Jason C. Poole, Lisa Jacobson, Frank J. Pallela, Jay Bream, Douglas C. Wallace, Stephen J. O'Brien
Biology Faculty Articles

Extended IL10 Haplotypes and their Association with HIV Progression to AIDS, T. K. Oleksyk, Sadeep Shrestha, Ann L. Truelove, James J. Goedert, Sharyne Donfield, John Phair, Shruti Mehta, Stephen J. O'Brien, M. W. Smith
Biology Faculty Articles

Evaluation of Nonviral Risk Factors for Nasopharyngeal Carcinoma in a High-Risk Population of Southern China, Xiuchan Guo, Randall C. Johnson, Hong Deng, Jian Liao, Li Guan, George W. Nelson, Mingzhong Tang, Yuming Zheng, Guy de The, Stephen J. O'Brien, Cheryl Winkler, Yi Zeng
Biology Faculty Articles

Association of Y Chromosome Haplogroup I with HIV Progression, and HAART Outcome, Efe Sezgin, Joanne M. Lind, Sadeep Shrestha, Sher L. Hendrickson, James J. Goedert, Sharyne Donfield, Gregory D. Kirk, John Phair, Jennifer L. Troyer, Stephen J. O'Brien, Michael W. Smith
Biology Faculty Articles

Stewardship of Human Biospecimens, DNA, Genotype, and Clinical Data in the GWAS Era, Stephen J. O'Brien
Biology Faculty Articles

Unsung Hero Robert C. Gallo, Giovanni Abbadessa, Roberto Accolla, Fernando Aiuti, Adriana Albini, Anna Aldovini, Massimo Alfano, Guido Antonelli, Courtenay Bartholomew, Zvi Bentwich, Umberto Bertazzoni, Jay A. Berzofsky, Peter Biberfeld, Enzo Boeri, Luigi Buonaguro, Franco M. Buonaguro, Michael Bukrinsky, Arsene Burny, Arnaldo Caruso, Sharon Cassol, Prakash Chandra, Luca Ceccherini-Nelli, Luigi Chieco-Bianchi, Mario Clerici, Sandra Colombini-Hatch, Carlo de Giuli Morghen, Andrea de Maria, Anita de Rossi, Manfred Dierich, Riccardo Della-Favera, Antonina Dolei, Daniel Douek, Volker Erfle, Barbara Felber, Simona Fiorentini, Genoveffa Franchini, Jonathan M. Gershoni, Frances Gotch, Patrick Green, Warner C. Greene, William Hall, William Haseltine, Stephens Jacobson, Lars O. Kallings, Vaniambadi S. Kalyanaraman, Hermann Katinger, Kamel Khalili, George Klein, Eva Klein, Mary Klotman, Paul Klotman, Moshe Kotler, Reinhard Kurth, Alain Lafeuillade, Michelangelo La Placa, Jonathan Lewis, Flavia Lillo, Julianna Lisziewicz, Anita Lomonico, Lucia Lopalco, Franco Lori, Paolo Lusso, Beatrice Macchi, Michael Malim, Leonid Margolis, Phillip D. Markham, Myra McClure, Nancy Miller, Maria C. Mingari, Lorenzo Moretta, Douglas Noonan, Stephen J. O'Brien, Takashi Okamoto, Ranajit Pal, Peter Palese, Amos Panet, Giuseppe Pantaleo, George Pavlakis, Mauro Pistello, Stanley Plotkin, Guido Poli, Roger Pomerantz, Antonia Radaelli, Marjorie Robert-Guroff, Mario Roederer, Mangalasseril G. Sarngadharan, Dominique Schols, Paola Secchiero, Gene M. Shearer, Antonio Siccardi, Mario Stevenson, Jan Svoboda, Jim Tartaglia, Giuseppe Torelli, Maria L. Tornesello, Erwin Tschachler, Mauro Vaccarezza, Angelika Vallbracht, Jan van Lunzen, Oliviero Varnier, Elisa Vicenzi, Harald von Melchner, Isaac Witz, Daniel Zagury, Jean-Francois Zagury, Giorgio Zauli, Donaldo Zipeto
Biology Faculty Articles

Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins, Rebecca S. LaRue, Valgerdur Andresdottir, Yannick Blanchard, Silvestro G. Conticello, David Derse, Michael Emerman, Warner C. Greene, Stefan R. Jonsson, Nathaniel R. Landau, Martin Lochelt, Harmit S. Malik, Michael H. Malim, Carsten Munk, Stephen J. O'Brien, Vinay K. Pathak, Klaus Strebel, Simon Wain-Hobson, Xiao-Fang Yu, Naoya Yuhki, Reuben S. Harris
Biology Faculty Articles

Mitochondrial DNA Haplogroups Influence AIDS Progression, Sher L. Hendrickson, Holli Hutcheson, Eduardo Ruiz-Pesini, Jason C. Poole, J. A. Lautenberger, Efe Sezgin, Lawrence Kingsley, James J. Goedert, David Vlahov, Sharyne Donfield, Douglas C. Wallace, Stephen J. O'Brien
Biology Faculty Articles

Host Genetic Influences on Highly Active Antiretroviral Therapy Efficacy and AIDS-Free Survival, Sher L. Hendrickson, Lisa Jacobson, George W. Nelson, John Phair, J. A. Lautenberger, Randall C. Johnson, Lawrence Kingsley, Joseph Margolick, Roger Detels, James J. Goedert, Stephen J. O'Brien
Biology Faculty Articles

Epizootiology and Management of Feline Leukemia Virus in the Florida Puma, Mark W. Cunningham, Meredith Brown, David B. Shindle, Scott P. Terrell, Kathleen A. Hayes, Bambi C. Ferree, R. T. McBride, Emmett L. Blankenship, Deborah Jansen, S. Citino, Melody E. Roelke, Richard A. Kiltie, Jennifer L. Troyer, Stephen J. O'Brien
Biology Faculty Articles

GSTM1 and GSTT1 Gene Deletions and the Risk for Nasopharyngeal Carcinoma in Han Chinese, Xiuchan Guo, Stephen J. O'Brien, Yi Zeng, Cheryl Winkler
Biology Faculty Articles

Evaluation of IL10, IL19 and IL20 Gene Polymorphisms and Chronic Hepatitis B Infection Outcome, Ann L. Truelove, T. K. Oleksyk, Sadeep Shrestha, Chloe L. Thio, James J. Goedert, Sharyne Donfield, Gregory D. Kirk, David L. Thomas, Stephen J. O'Brien, Michael W. Smith
Biology Faculty Articles

Detecting AIDS Restriction Genes: from Candidate Genes to Genome-Wide Association Discovery, Holli Hutcheson, J. A. Lautenberger, G. W. Nelson, J. U. Pontius, Bailey Kessing, Cheryl Winkler, M. W. Smith, R. Johnson, R. Stephens, John Phair, James J. Goedert, Sharyne Donfield, Stephen J. O'Brien
Biology Faculty Articles

Exposure to Disease Agents in the Endangered Iberian Lynx (Lynx pardinus), Melody E. Roelke, Warren E. Johnson, Javier Millan, Francisco Palomares, Eloy Revilla, Alejandro Rodriguez, Javier Calzada, Pablo Ferreras, Luis Leon-Vizcaino, Miguel Delibes, Stephen J. O'Brien
Biology Faculty Articles

Evolution of Feline Immunodeficiency Virus in Felidae: Implications for Human Health and Wildlife Ecology, Jill Pecon-Slattery, Jennifer L. Troyer, Warren E. Johnson, Stephen J. O'Brien
Biology Faculty Articles

FIV Cross-Species Transmission: An Evolutionary Prospective, Jennifer L. Troyer, Sue VandeWoude, Jill Pecon-Slattery, Carl McIntosh, Sam Franklin, Agostinho Antunes, Warren E. Johnson, Stephen J. O'Brien
Biology Faculty Articles

Identifying Selected Regions from Heterozygosity and Divergence Using a Light-Coverage Genomic Dataset from Two Human Populations, T. K. Oleksyk, Kai Zhao, Francisco M. De La Vega, Dennis A. Gilbert, Stephen J. O'Brien, Michael W. Smith
Biology Faculty Articles

Genomic Organization, Sequence Divergence, and Recombination of Feline Immunodeficiency Virus from Lions in the Wild, Jill Pecon-Slattery, Carrie L. McCracken, Jennifer L. Troyer, Sue VandeWoude, Melody E. Roelke, Kerry Sondgeroth, Christiaan Winterbach, Stephen J. O'Brien
Biology Faculty Articles

Genetic Characterization of Feline Leukemia Virus from Florida Panthers, Meredith Brown, Mark W. Cunningham, Alfred L. Roca, Jennifer L. Troyer, Warren E. Johnson, Stephen J. O'Brien
Biology Faculty Articles

A Population-Based Study to Investigate Host Genetic Factors Associated with Hepatitis B Infection and Pathogenesis in the Chinese Population, Zheng Zheng, Li Guan, Ping An, Shan Sun, Stephen J. O'Brien, Cheryl Winkler, HBV Study Consortium
Biology Faculty Articles

A Mutation in KIR3DS1 That Results in Truncation and Lack of Cell Surface Expression, Maureen P. Martin, Veronique Pascal, Meredith Yeager, John Phair, Gregory D. Kirk, Keith Hoots, Stephen J. O'Brien, Stephen K. Anderson, Mary Carrington
Biology Faculty Articles

Regulatory Polymorphisms in the Cyclophilin A Gene, PPIA, Accelerate Progression to AIDS, Ping An, Li Hua Wang, Holli Hutcheson-Dilks, George Nelson, Sharyne Donfield, James J. Goedert, Charles Rinaldo, Susan Buchbinder, Gregory D. Kirk, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Innate Partnership of HLA-B and KIR3DL1 Subtypes Against HIV-1, Maureen P. Martin, Ying Qi, Xiaojiang Gao, Eriko Yamada, Jeffrey N. Martin, Florencia Fereyra, Sara Colombo, Elizabeth E. Brown, W. Lesley Shupert, John Phair, James J. Goedert, Susan Buchbinder, Gregory D. Kirk, Amalio Telenti, Mark Connors, Stephen J. O'Brien, Bruce D. Walker, Peter Parham, Steven G. Deeks, Daniel W. McVicar, Mary Carrington
Biology Faculty Articles

Mutation in CEP290 Discovered for Cat Model of Human Retinal Degeneration, Marilyn Menotti-Raymond, Victor A. David, Alejandro A. Schaffer, R. Stephens, David Wells, Rajendra Kumar-Singh, Stephen J. O'Brien, Kristina Narfstrom
Biology Faculty Articles

Q&A: Stephen J. O'Brien, Stephen J. O'Brien
Biology Faculty Articles

Polymorphisms of CUL5 are Associated with CD4+ T Cell Loss in HIV-1 Infected Individuals, Ping An, Priya Duggal, Li Hua Wang, Stephen J. O'Brien, Sharyne Donfield, James J. Goedert, John Phair, Susan Buchbinder, Gregory D. Kirk, Cheryl Winkler
Biology Faculty Articles

Elevated Male European and Female African Contributions to the Genomes of African American Individuals, Joanne M. Lind, Holli Hutcheson-Dilks, Scott M. Williams, Jason H. Moore, Myron Essex, Eduardo Ruiz-Pesini, Douglas C. Wallace, Sarah A. Tishkoff, Stephen J. O'Brien, Michael W. Smith
Biology Faculty Articles

HLA-B Bw4 Alleles and HIV-1 Transmission in Heterosexual Couples, Tania M. Welzel, Xiaojiang Gao, Ruth M. Pfeiffer, Maureen P. Martin, Stephen J. O'Brien, Mary Carrington, Thomas R. O'Brien
Biology Faculty Articles

Genetic Protection against Hepatitis B Virus Conferred by CCR5Δ32: Evidence that CCR5 Contributes to Viral Persistence, Chloe L. Thio, Jacquie Astemborski, Arman A. Bashirova, Timothy L. Mosbruger, Spencer Greer, Mallory D. Witt, James J. Goedert, Margaret Hilgartner, Audrey Majesk, Stephen J. O'Brien, David L. Thomas, Mary Carrington
Biology Faculty Articles

An ∼140-kb Deletion Associated with Feline Spinal Muscular Atrophy Implies an Essential LIX1 Function for Motor Neuron Survival, John C. Fyfe, Marilyn Menotti-Raymond, Victor A. David, Lars Brichta, Alejandro A. Schaffer, R. Agarwala, William J. Murphy, William J. Wedemeyer, Brittany L. Gregory, Bethany G. Buzzell, Meghan C. Drummond, Brunhilde Wirth, Stephen J. O'Brien
Biology Faculty Articles

Plagues and Adaptation: Lessons from the Felidae Models for SARS and AIDS, Stephen J. O'Brien, Jennifer L. Troyer, Melody E. Roelke, L. Marker, Jill Pecon-Slattery
Biology Faculty Articles

KIR/HLA Pleiotropism: Protection against Both HIV and Opportunistic Infections, Ying Qi, Maureen P. Martin, Xiaojiang Gao, Lisa Jacobson, James J. Goedert, Susan Buchbinder, Gregory D. Kirk, Stephen J. O'Brien, John Trowsdale, Mary Carrington
Biology Faculty Articles

Genetic Variation in the CCL18-CCL3-CCL4 Chemokine Gene Cluster Influences HIV Type 1 Transmission and AIDS Disease Progression, William Modi, J. A. Lautenberger, Ping An, Kevin Scott, James J. Goedert, Gregory D. Kirk, Susan Buchbinder, John Phair, Sharyne Donfield, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Using Mutual Information to Measure the Impact of Multiple Genetic Factors on AIDS, George W. Nelson, Stephen J. O'Brien
Biology Faculty Articles

Consistent Effects of TSG101 Genetic Variability on Multiple Outcomes of Exposure to Human Immunodeficiency Virus Type 1, Arman A. Bashirova, Gabriela Bleiber, Ying Qi, Holli Hutcheson, Traci Yamashita, Randall C. Johnson, Jie Cheng, Galit Alter, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Margaret May, Frank Maldarelli, Lisa Jacobson, Stephen J. O'Brien, Amalio Telenti, Mary Carrington
Biology Faculty Articles

Genetic Factors Leading to Chronic Epstein–Barr Virus Infection and Nasopharyngeal Carcinoma in South East China: Study Design, Methods and Feasibility, Xiu Chan Guo, Kevin Scott, Yan Liu, Michael Dean, Victor David, George W. Nelson, Randall C. Johnson, Holli H. Dilks, J. A. Lautenberger, Bailey Kessing, Janice S. Martenson, Li Guan, Shan Sun, Hong Deng, Yuming Zheng, Guy de The, Jian Liao, Yi Zeng, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

T-Lymphocyte Profiles in FIV-Infected Wild Lions and Pumas Reveal CD4 Depletion, Melody E. Roelke, Jill Pecon-Slattery, S. Taylor, S. Citino, E. Brown, Craig Packer, Sue VandeWoude, Stephen J. O'Brien
Biology Faculty Articles

Diversity of MICA and Linkage Disequilibrium with HLA-B in Two North American Populations, Xiaojiang Gao, Richard M. Single, Peter Karacki, Darlene Marti, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Searching for Signals of Evolutionary Selection in 168 Genes Related to Immune Function, Emily C. Walsh, Pardis Sabeti, Holli Hutcheson, Ben Fry, Stephen F. Schaffner, Paul I. W. de Bakker, Patrick Varilly, Alejandro A. Palma, Jessica Roy, Richard Cooper, Cheryl Winkler, Yi Zeng, Guy de The, Eric S. Lander, Stephen J. O'Brien, David Altshuler
Biology Faculty Articles

A Variant of the Gene Encoding Leukotriene A4 Hydrolase Confers Ethnicity-Specific Risk of Myocardial Infarction, Anna Helgadottir, Andrei Manolescu, Agnar Helgason, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Solveig Gretarsdottir, Kristinn P. Magnusson, Gudmundur Gudmundsson, Andrew Hicks, Thorlakur Jonsson, Struan F. A. Grant, Jesus Sainz, Stephen J. O'Brien, Sigurlaug Sveinbjornsdottir, Einar M. Valdimarsson, Stefan E. Matthiasson, Allan I. Levey, Jerome L. Abramson, Murdach P. Reilly, Viola Vaccarino, Megan L. Wolfe, Vilmundur Gudnason, Arshed A. Quyyumi, Eric J. Topol, Daniel J. Rader, Gudmundur Thorgeirsson, Jeffrey R. Gulcher, Hakon Hakonarson, Augustine Kong, Kari Stefansson
Biology Faculty Articles

Behavioral Risk Exposure and Host Genetics of Susceptibility to HIV-1 Infection, Sadeep Shrestha, Steffanie A. Strathdee, Noya Galai, T. K. Oleksyk, M. Daniele Fallin, Shruti Mehta, Daniel Schaid, David Vlahov, Stephen J. O'Brien, Matthew W. Smith
Biology Faculty Articles

Haplotype Analysis of the SDF-1 (CXCL12) Gene in a Longitudinal HIV-1/AIDS Cohort Study, William Modi, K. Scott, James J. Goedert, David Vlahov, Susan Buchbinder, Roger Detels, Sharyne Donfield, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

AIDS Restriction HLA Allotypes Target Distinct Intervals of HIV-1 Pathogenesis, Xiaojiang Gao, Arman A. Bashirova, Astrid K. N. Iversen, John Phair, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Marcus Altfeld, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Genomes and Evolution: The Power of Comparative Genomics, Stephen J. O'Brien, Claire M. Fraser
Biology Faculty Articles

The Case for Selection at CCR5-Δ32, Pardis Sabeti, Emily C. Walsh, Stephen F. Schaffner, Patrick Varilly, Ben Fry, Holli Hutcheson, Mike Cullen, Tarjei S. Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen J. O'Brien, Eric S. Lander
Biology Faculty Articles

Stromal Cell–Derived Factor–1 Genotype, Coreceptor Tropism, and HIV Type 1 Disease Progression, Eric S. Daar, Henry S. Lynn, Sharyne Donfield, Alice Lail, Stephen J. O'Brien, Wei Huang, Cheryl Winkler
Biology Faculty Articles

An STR Forensic Typing System for Genetic Individualization of Domestic Cat (Felis catus) Samples, J. M. Butler, Leslie Wachter, Marilyn Menotti-Raymond, Stephen J. O'Brien, V. A. David
Biology Faculty Articles

Mannose Binding Lectin Genotypes Influence Recovery from Hepatitis B Virus Infection, Chloe L. Thio, Timothy L. Mosbruger, Jacquie Astemborski, Spencer Greer, Gregory D. Kirk, Stephen J. O'Brien, David L. Thomas
Biology Faculty Articles

Single Nucleotide Polymorphisms and Haplotypes in the IL10 Region Associated with HCV Clearance, T. K. Oleksyk, Chloe L. Thio, Ann L. Truelove, James J. Goedert, Sharyne Donfield, Gregory D. Kirk, D. L. Thomas, Stephen J. O'Brien, M. W. Smith
Biology Faculty Articles

The Linkage Disequilibrium Maps of Three Human Chromosomes Across Four Populations Reflect Their Demographic History and a Common Underlying Recombination Pattern, Francisco M. De La Vega, Hadar Isaac, Andrew Collins, Charles R. Scafe, Bjarni V. Halldorsson, Xiaoping Su, Ross A. Lippert, Yu Wang, Marion Laig-Webster, Ryan T. Koehler, Janet S. Ziegle, Lewis T. Wogan, Junko F. Stevens, Kyle M. Leinen, Sheri J. Olson, Karl J. Guegler, Xiaoqing You, Lily H. Xu, Heinz G. Hemken, Francis Kalush, Mitsuo Itakura, Yi Zheng, Guy de The, Stephen J. O'Brien, Andrew G. Clark, Sorin Istrail, Michael W. Hunkapiller, Eugene G. Spier, Dennis A. Gilbert
Biology Faculty Articles

Insertional Polymorphisms of Endogenous Feline Leukemia Viruses, Alfred L. Roca, William G. Nash, Joan C. Menninger, William J. Murphy, Stephen J. O'Brien
Biology Faculty Articles

The Effect of RANTES Chemokine Genetic Variants on Early HIV-1 Plasma RNA Among African American Injection Drug Users, Priya Duggal, Cheryl Winkler, Ping An, Xiao-Fang Yu, Homayoon Farzadegan, Stephen J. O'Brien, T. H. Beaty, David Vlahov
Biology Faculty Articles

Inherited Motor Neuron Disease in Domestic Cats: A Model of Spinal Muscular Atrophy, Qianchuan He, Charles Lowrie, G. Diane Shelton, Rudy J. Castellani, Marilyn Menotti-Raymond, William J. Murphy, Stephen J. O'Brien, William Swanson, John C. Fyfe
Biology Faculty Articles

Dominant Effects of CCR2-CCR5 Haplotypes in HIV-1 Disease Progression, Cheryl Winkler, Houria Hendel, Mary Carrington, Michael W. Smith, George W. Nelson, Stephen J. O'Brien, John Phair, David Vlahov, Lisa Jacobson, Jay Rappaport, Alexandre Vasilescu, Sebastien Berlin-Maghit, Ping An, Wei Lu, Jean-Marie Andrieu, Francois Schachter, Amu Therwath, Jean-Francois Zagury
Biology Faculty Articles

Association of DC-SIGN Promoter Polymorphism with Increased Risk for Parenteral, but Not Mucosal, Acquisition of Human Immunodeficiency Virus Type 1 Infection, Maureen P. Martin, Michael M. Lederman, Holli B. Hutcheson, James J. Goedert, George W. Nelson, Yvette van Kooyk, Roger Detels, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Lack of Associations Between HLA Class II Alleles and Resistance to HIV-1 Infection Among White, Non-Hispanic Homosexual Men, Chenglong Liu, Mary Carrington, Richard A. Kaslow, Xiaojiang Gao, Charles Rinaldo, Lisa Jacobson, Joseph Margolick, John Phair, Stephen J. O'Brien, Roger Detels
Biology Faculty Articles

APOBEC3G Genetic Variants and Their Influence on the Progression to AIDS, Ping An, Gabriela Bleiber, Priya Duggal, George Nelson, Margaret May, Bastien Mangeat, Irene Alobwede, Didier Trono, David Vlahov, Sharyne Donfield, James J. Goedert, John Phair, Susan Buchbinder, Stephen J. O'Brien, Amalio Telenti, Cheryl Winkler
Biology Faculty Articles

Cytotoxic T-Lymphocyte Antigen 4 Gene and Recovery from Hepatitis B Virus Infection, Chloe L. Thio, Timothy L. Mosbruger, Richard A. Kaslow, Christopher L. Karp, Steffanie A. Strathdee, David Vlahov, Stephen J. O'Brien, Jacquie Astemborski, David L. Thomas
Biology Faculty Articles

Adam's Curse: A Future Without Men, Stephen J. O'Brien
Biology Faculty Proceedings, Presentations, Speeches, Lectures

HLA and NK Cell Inhibitory Receptor Genes in Resolving Hepatitis C Virus Infection, Salim I. Khakoo, Chloe L. Thio, Maureen P. Martin, Collin R. Brooks, Xiaojiang Gao, Jacquie Astemborski, Jie Cheng, James J. Goedert, David Vlahov, Margaret Hilgartner, Steven Cox, Ann-Margeret Little, Graeme J. Alexander, Matthew E. Cramp, Stephen J. O'Brien, William M. C. Rosenberg, David L. Thomas, Mary Carrington
Biology Faculty Articles

An Analysis of Tumor Necrosis Factor α Gene Polymorphisms and Haplotypes with Natural Clearance of Hepatitis C Virus Infection, Chloe L. Thio, James J. Goedert, Timothy L. Mosbruger, David Vlahov, Steffanie A. Strathdee, Stephen J. O'Brien, Jacquie Astemborski, D. L. Thomas
Biology Faculty Articles

MICA and Recovery from Hepatitis C Virus and Hepatitis B Virus Infections, Peter Karacki, Xiaojiang Gao, Chloe L. Thio, D. L. Thomas, James J. Goedert, David Vlahov, Richard A. Kaslow, Steffanie A. Strathdee, Margaret Hilgartner, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Evaluating Association and Transmission of Eight Inflammatory Genes with Viliuisk Encephalomyelitis Susceptibility, T. K. Oleksyk, L. G. Goldfarb, T. Sivtseva, A. P. Danilova, V. L. Osakovsky, S. Shrestha, Stephen J. O'Brien, M. W. Smith
Biology Faculty Articles

Human Genes That Limit AIDS, Stephen J. O'Brien, George W. Nelson
Biology Faculty Articles

A High-Density Admixture Map for Disease Gene Discovery in African Americans, MIchael W. Smith, Nick Patterson, J. A. Lautenberger, Ann L. Truelove, Gavin J. McDonald, Alicja Waliszewska, Andre A. Mignault, Zeng Yi, Guy de The, Myron Essex, Jean-Louis Sankale, Jason H. Moore, Kwabena Poku, John Phair, James J. Goedert, David Vlahov, Scott M. Williams, Sarah A. Tishkoff, Cheryl Winkler, Francisco M. De La Vega, Trevor Woodage, John J. Sninsky, David A. Hafler, David Altshuler, Dennis A. Gilbert, Stephen J. O'Brien, David Reich
Biology Faculty Articles

Methods for High-Density Admixture Mapping of Disease Genes, Nick Patterson, Neil Hattangadi, Barton Lane, Kirk E. Lohmueller, David A. Hafler, Jorge R. Oksenberg, Stephen L. Hauser, MIchael W. Smith, Stephen J. O'Brien, David Altshuler, Mark J. Daly, David Reich
Biology Faculty Articles

Patterns of Ethnic Diversity Among the Genes That Influence AIDS, Cheryl Winkler, Ping An, Stephen J. O'Brien
Biology Faculty Articles

Genomically Intact Endogenous Feline Leukemia Viruses of Recent Origin, Alfred L. Roca, Jill Pecon-Slattery, Stephen J. O'Brien
Biology Faculty Articles

Coronavirus Outbreak in Cheetahs: Lessons for SARS, A. J. Pearks Wilkerson, Emma C. Teeling, Jennifer L. Troyer, Gila Kahila Bar-Gal, Melody E. Roelke, Laurie Marker, Jill Pecon-Slattery, Stephen J. O'Brien
Biology Faculty Articles

Fraction of Cases of Acquired Immunodeficiency Syndrome Prevented by the Interactions of Identified Restriction Gene Variants, M. J. Silverberg, M. W. Smith, Joan S. Chmiel, Roger Detels, Joseph Margolick, Charles Rinaldo, Stephen J. O'Brien, A. Muñoz
Biology Faculty Articles

Seroprevalence of Toxoplasma gondii in American Free-Ranging or Captive Pumas (Felis concolor) and Bobcats (Lynx rufus), Yoko Kikuchi, B. B. Chomel, R. W. Kasten, Janice S. Martenson, Pamela K. Swift, Stephen J. O'Brien
Biology Faculty Articles

Public Stem Cell Banks: Considerations of Justice in Stem Cell Research and Therapy, Ruth R. Faden, Liza Dawson, Alison S. Bateman-House, Dawn Mueller Agnew, Hilary Bok, Dan W. Brock, Aravinda Chakravarti, Xiaojiang Gao, Mark Greene, Patricia A. King, Stephen J. O'Brien, David H. Sachs, Kathryn E. Schill, Andrew Siegel, Davor Solter, Sonia M. Suter, Catherine M. Verfaillie, LeRoy B. Walters, John Gearhart
Biology Faculty Articles

Safety Issues in Cell-Based Intervention Trials, Liza Dawson, Alison S. Bateman-House, Dawn Mueller Agnew, Hilary Bok, Dan W. Brock, Aravinda Chakravarti, Mark Greene, Patricia A. King, Stephen J. O'Brien, David H. Sachs, Kathryn E. Schill, Andrew Siegel, Davor Solter, Sonia M. Suter, Catherine M. Verfaillie, LeRoy B. Walters, John Gearhart, Ruth R. Faden
Biology Faculty Articles

Reconstructing the Genomic Architecture of Mammalian Ancestors Using Multispecies Comparative Maps, William J. Murphy, Guillaume Bourque, Glenn Tesler, Pavel Pevzner, Stephen J. O'Brien
Biology Faculty Articles

Non-Hodgkin's B Cell Lymphoma in Persons with Acquired Immunodeficiency Syndrome is Associated with Increased Serum Levels of IL10, or the IL10 Promoter −592 C/C Genotype, Elizabeth Crabb Breen, W. John Boscardin, Roger Detels, Lisa Jacobson, Michael W. Smith, Stephen J. O'Brien, Joan S. Chmiel, Charles Rinaldo, Shenghan Lai, Otoniel Martinez-Maza
Biology Faculty Articles

MCP-1-MCP-3–Eotaxin Gene Cluster Influences HIV-1 Transmission, William Modi, James J. Goedert, Steffanie A. Strathdee, Susan Buchbinder, Roger Detels, Sharyne Donfield, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

A Dog's Breakfast?, Stephen J. O'Brien, William J. Murphy
Biology Faculty Articles

A Tumor Necrosis Factor-α-Inducible Promoter Variant of Interferon-γ Accelerates CD4+ T Cell Depletion in Human Immunodeficiency Virus-1-Infected Individuals, Ping An, David Vlahov, Joseph Margolick, John Phair, Thomas R. O'Brien, J. A. Lautenberger, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Haplotype Diversity in the Interleukin-4 Gene is Not Associated with HIV-1 transmission and AIDS Progression, William Modi, Thomas R. O'Brien, David Vlahov, Susan Buchbinder, Edward Gomperts, John Phair, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Genetic Influence of CXCR6 Chemokine Receptor Alleles on PCP-Mediated AIDS Progression Among African Americans, Priya Duggal, P. An, T. H. Beaty, Steffanie A. Strathdee, H. Farzadegan, R. D. Markham, L. Johnson, Stephen J. O'Brien, David Vlahov, Cheryl Winkler
Biology Faculty Articles

Quantitative Polymerase Chain Reaction-based Assay for Estimating DNA Yield Extracted from Domestic Cat Specimens, Marilyn Menotti-Raymond, Victor David, Leslie Wachter, Naoya Yuhki, Stephen J. O'Brien
Biology Faculty Articles

Association of Polymorphisms in Human Leukocyte Antigen Class I and Transporter Associated with Antigen Processing Genes with Resistance to Human Immunodeficiency Virus Type 1 Infection, Chenglong Liu, Mary Carrington, Richard A. Kaslow, Xiaojiang Gao, Charles Rinaldo, Lisa Jacobson, Joseph Margolick, John Phair, Stephen J. O'Brien, Roger Detels
Biology Faculty Articles

Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+-T-Cell Responses for Groups of HIV-1-Infected Individuals with Different HLA-B*35 Genotypes, Xia Jin, Xiaojiang Gao, Murugappan Ramanathan Jr., Geoffrey R. Deschenes, George W. Nelson, Stephen J. O'Brien, James J. Goedert, David D. Ho, Thomas R. O'Brien, Mary Carrington
Biology Faculty Articles

Feline Immunodeficiency Virus Integration in B-Cell Lymphoma Identifies a Candidate Tumor Suppressor Gene on Human Chromosome 15q151, Julia Beatty, Anne Terry, Julie MacDonald, Elizabeth Gault, Stanley Cevario, Stephen J. O'Brien, Ewan Cameron, James C. Neil
Biology Faculty Articles

Balanced Polymorphism Selected by Genetic Versus Infectious Human Disease, Michael Dean, Mary Carrington, Stephen J. O'Brien
Biology Faculty Articles

Immunologic Profile of Highly Exposed Yet HIV Type 1-Seronegative Men, Otto Yang, W. John Boscardin, Jose Matud, Mary Ann Hausner, Lance E. Hultin, Patricia M. Hultin, Roger Shih, John Ferbas, Frederick P. Siegal, Michael Shodell, Gene M. Shearer, Edith Grene, Mary Carrington, Stephen J. O'Brien, Charles B. Price, Roger Detels, Beth D. Jamieson, Janis Giorgi
Biology Faculty Articles

Epistatic Interaction Between KIR3DS1 and HLA-B Delays the Progression to AIDS, Maureen P. Martin, Xiaojiang Gao, Jeong-Hee Lee, George W. Nelson, Roger Detels, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, John Trowsdale, Michael Wilson, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Modulating Influence on HIV/Aids by Interacting RANTES Gene Variants, Ping An, George W. Nelson, Lihua Wang, Sharyne Donfield, James J. Goedert, John Phair, David Vlahov, Susan Buchbinder, William L. Farrar, William Modi, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

HLA-Cw*04 and Hepatitis C Virus Persistence, Chloe L. Thio, Xiaojiang Gao, James J. Goedert, David Vlahov, Kenrad E. Nelson, Margaret Hilgartner, Stephen J. O'Brien, Peter Karacki, Jacquie Astemborski, Mary Carrington, David L. Thomas
Biology Faculty Articles

HIV-1 Infection in Individuals With the CCR5-Δ32/Δ32 Genotype: Acquisition of Syncytium-Inducing Virus at Seroconversion, Haynes W. Sheppard, Nelson L. Michael, Stephen J. O'Brien, Michael Dean, Mary Carrington, Dale Dondero, Susan Buchbinder
Biology Faculty Articles

The Importance of Assessing Effect Modification When Asserting Racial Differences in Associations Between Human Leukocyte Antigen Class II Alleles and Hepatitis C Virus Outcomes, Chloe L. Thio, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Considering Genetic Profiles in Functional Studies of Immune Responsiveness to HIV-1, Mary Carrington, George Nelson, Stephen J. O'Brien
Biology Faculty Articles

Markers for Mapping by Admixture Linkage Disequilibrium in African American and Hispanic Populations, Michael W. Smith, J. A. Lautenberger, Hyoung Doo Shin, Jean-Paul Chretien, Sadeep Shrestha, Dennis A. Gilbert, Stephen J. O'Brien
Biology Faculty Articles

HLA and AIDS: A Cautionary Tale, Stephen J. O'Brien, Xiaojiang Gao, Mary Carrington
Biology Faculty Articles

MHC Class I Molecules and Progression to AIDS, Mary Carrington, Xiaojiang Gao, Stephen J. O'Brien
Biology Faculty Articles

Racial Differences in HLA Class II Associations with Hepatitis C Virus Outcomes, Chloe L. Thio, David L. Thomas, James J. Goedert, David Vlahov, Kenrad E. Nelson, Margaret Hilgartner, Stephen J. O'Brien, Peter Karacki, Darlene Marti, Jacquie Astemborski, Mary Carrington
Biology Faculty Articles

Cell Culture Forensics, Stephen J. O'Brien
Biology Faculty Articles

Effect of a Single Amino Acid Change in MHC Class I Molecules on the Rate of Progression to AIDS, Xiaojiang Gao, George W. Nelson, Peter Karacki, Maureen P. Martin, John Phair, Richard A. Kaslow, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Immunologic and Virologic Response to Highly Active Antiretroviral Therapy in the Multicenter AIDS Cohort Study, Traci Yamashita, John Phair, A. Muñoz, Joseph Margolick, Roger Detels, Stephen J. O'Brien, John Mellors, Steven M. Wolinsky, Lisa Jacobson
Biology Faculty Articles

Validation of Genetic Case-Control Studies in AIDS and Application to the CX3CR1 Polymorphism, Houria Hendel, Cheryl Winkler, Ping An, Elisabeth Roemer-Binns, George Nelson, Philippe Haumont, Stephen J. O'Brien, Kamel Khalilli, Jean-Francois Zagury, Jay Rappaport, Jean-Francois Zagury
Biology Faculty Articles

Hepatitis C Virus Load is Associated with Human Immunodeficiency Virus Type 1 Disease Progression in Hemophiliacs, Eric S. Daar, Henry Lynn, Sharyne Donfield, Edward Gomperts, Stephen J. O'Brien, Margaret Hilgartner, Keith Hoots, David Chernoff, Steven Arkin, W.-Y. Wong, Cheryl Winkler, Hemophilia Growth and Development Study
Biology Faculty Articles

Genetic Restriction of HIV-1 Pathogenesis to AIDS by Promoter Alleles of IL10, Hyoung Doo Shin, Cheryl Winkler, J. Claiborne Stephens, Jay Bream, Howard Young, James J. Goedert, Thomas R. O'Brien, David Vlahov, Susan Buchbinder, Janis Giorgi, Charles Rinaldo, Sharyne Donfield, Anne Willoughby, Stephen J. O'Brien, Michael W. Smith
Biology Faculty Articles

Genetic Heterogeneity and Molecular Epidemiology of GB Virus C/Hepatitis G Virus in China, Ping An, H. Luo, T. Lu, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

The Effect of Genetic Variation in Chemokines and Their Receptors on HIV Transmission and Progression to AIDS, Stephen J. O'Brien, John P. Moore
Biology Faculty Articles

Influence of CCR5 Promoter Haplotypes on AIDS Progression in African–Americans, Ping An, Maureen P. Martin, George W. Nelson, Mary Carrington, Michael W. Smith, Kui Gong, David Vlahov, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Unusual Polymorphisms in Human Immunodeficiency Virus Type 1 Associated with Nonprogressive Infection, Louis Alexander, Emma Weiskopf, Thomas C. Greenough, Nathan C. Gaddis, Marcy C. Auerbach, MIchael H. Malim, Stephen J. O'Brien, Bruce D. Walker, John L. Sullivan, Ronald C. Desrosiers
Biology Faculty Articles

Significant Admixture Linkage Disequilibrium Across 30 cM Around the FY Locus in African Americans, J. A. Lautenberger, J. Claiborne Stephens, Stephen J. O'Brien, Michael W. Smith
Biology Faculty Articles

Polygenic and Multifactorial Disease Gene Association in Man: Lessons from AIDS, Stephen J. O'Brien, George W. Nelson, Cheryl Winkler, Michael W. Smith
Biology Faculty Articles

Extensive Conservation of Sex Chromosome Organization Between Cat and Human Revealed by Parallel Radiation Hybrid Mapping, William J. Murphy, Shan Sun, Zhang-Qun Chen, Jill Pecon-Slattery, Stephen J. O'Brien
Biology Faculty Articles

Long-Term Nonprogressive Infection with Human Immunodeficiency Virus Type 1 in a Hemophilia Cohort, Thomas C. Greenough, Doreen B. Brettler, Frank Kirchhoff, Louis Alexander, Stephen J. O'Brien, Mohan Somasundaran, Katherine Luzuriaga, John L. Sullivan
Biology Faculty Articles

Taxonomic Hierarchy of HLA Class I Allele Sequences, L. McKenzie, Jill Pecon-Slattery, Mary Carrington, Stephen J. O'Brien
Biology Faculty Articles

Distribution of Two HIV-1–Resistant Polymorphisms (SDF1-30A and CCR2-64I) in East Asian and World Populations and Its Implication in AIDS Epidemiology, Bing Su, Li Jin, Fang Hu, Junhua Xiao, Jingchun Luo, Daru Lu, Weiling Zhang, Jiayou Chu, Ruofu Du, Zhencheng Geng, Xinfang Qiu, Jinglun Xue, Jiazhen Tan, Stephen J. O'Brien, Ranajit Chakraborty
Biology Faculty Articles

Phenotypic Expressions of CCR5-Δ32/Δ32 Homozygosity, Giang T. Nguyen, Mary Carrington, Judith A. Beeler, Michael Dean, Louis M. Aledort, Philip M. Blatt, Alan R. Cohen, Donna DiMichele, M. Elaine Eyster, Craig M. Kessler, Barbara Konkle, Cindy Leissinger, Naomi Luban, Stephen J. O'Brien, James J. Goedert, Thomas R. O'Brien
Biology Faculty Articles

Reduced Risk of AIDS Lymphoma in Individuals Heterozygous for the CCR5-Δ32 Mutation, Michael Dean, Lisa Jacobson, Glen McFarlane, Joseph Margolick, Frank J. Jenkins, O. M. Zack Howard, Hui-Fang Dong, James J. Goedert, Susan Buchbinder, Edward Gomperts, David Vlahov, Joost J. Oppenheim, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Effects of Plasma HIV RNA, CD4+ T Lymphocytes, and the Chemokine Receptors CCR5 and CCR2b on HIV Disease Progression in Hemophiliacs, Eric S. Daar, Sharyne Donfield, Edward Gomperts, Margaret Hilgartner, Keith Hoots, David Chernoff, Cheryl Winkler, Stephen J. O'Brien, Hemophilia Growth and Development Study
Biology Faculty Articles

A Scan for Linkage Disequilibrium Across the Human Genome, Gavin A. Huttley, Michael W. Smith, Mary Carrington, Stephen J. O'Brien
Biology Faculty Articles

A Human Genome Map of Comparative Anchor Tagged Sequences, Z-Q. Chen, J. A. Lautenberger, Leslie A. Lyons, L. McKenzie, Stephen J. O'Brien
Biology Faculty Articles

Selection Against Susceptibility to HIV-1, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

New Class I and II HLA Alleles Strongly Associated with Opposite Patterns of Progression to AIDS, Houria Hendel, Sophie Caillat-Zucman, Helene Lebuanec, Mary Carrington, Stephen J. O'Brien, Jean-Marie Andrieu, Francois Schachter, Daniel Zagury, Jay Rappaport, Cheryl Winkler, George W. Nelson, Jean-Francois Zagury
Biology Faculty Articles

Development of a Feline Whole Genome Radiation Hybrid Panel and Comparative Mapping of Human Chromosome 12 and 22 Loci, William J. Murphy, Marilyn Menotti-Raymond, Leslie A. Lyons, Mary A. Thompson, Stephen J. O'Brien
Biology Faculty Articles

Class II HLA Alleles and Hepatitis B Virus Persistence in African Americans, Chloe L. Thio, Mary Carrington, Darlene Marti, Stephen J. O'Brien, David Vlahov, Kenrad E. Nelson, Jacquie Astemborski, David L. Thomas
Biology Faculty Articles

CCR5 Promoter Alleles and Specific DNA Binding Factors, Jay Bream, Howard A. Young, Nancy Rice, Maureen P. Martin, Michael W. Smith, Mary Carrington, Stephen J. O'Brien
Biology Faculty Articles

HLA and HIV-1: Heterozygote Advantage and B*35-Cw*04 Disadvantage, Mary Carrington, George W. Nelson, Maureen P. Martin, Teri Kissner, David Vlahov, James J. Goedert, Richard A. Kaslow, Susan Buchbinder, Keith Hoots, Stephen J. O'Brien
Biology Faculty Articles

Genetics of HIV-1 Infection: Chemokine Receptor Ccr5 Polymorphism and its Consequences, Mary Carrington, Michael Dean, Maureen P. Martin, Stephen J. O'Brien
Biology Faculty Articles

CXCR4 Polymorphisms and HIV-1 Pathogenesis, Maureen P. Martin, Mary Carrington, Michael Dean, Stephen J. O'Brien, Haynes W. Sheppard, Scott A. Wegner, Nelson L. Michael
Biology Faculty Articles

Distinctive Effects of CCR5, CCR2, and SDF1 Genetic Polymorphisms in AIDS Progression, Houria Hendel, N. Henon, Helene Lebuanec, Abderrahim Lachgar, H. Poncelet, Sophie Caillat-Zucman, Cheryl Winkler, Michael W. Smith, L. Kenefic, Stephen J. O'Brien, W. Lu, Jean-Marie Andrieu, Daniel Zagury, Francois Schachter, Jay Rappaport, Jean-Francois Zagury
Biology Faculty Articles

Genetic Acceleration of AIDS Progression by a Promoter Variant of CCR5, Maureen P. Martin, Michael Dean, Michael W. Smith, Cheryl Winkler, Bernard Gerrard, Nelson L. Michael, Benhur Lee, Robert W. Doms, Joseph Margolick, Susan Buchbinder, James J. Goedert, Thomas R. O'Brien, Margaret Hilgartner, David Vlahov, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Association of HLA Profiles with Early Plasma Viral Load, CD4+ Cell Count and Rate of Progression to AIDS Following Acute HIV‐1 Infection, A. J. Saah, Donald R. Hoover, Shingui Weng, Mary Carrington, John Mellors, Charles R. Rinaldo Jr., Dean Mann, R. Apple, John Phair, Roger Detels, Stephen J. O'Brien, Cheryl Enger, Pamela Johnson, Richard A. Kaslow, Multicenter AIDS Cohort Study
Biology Faculty Articles

Genetic Characterization of Canine Distemper Virus in Serengeti Carnivores, Margaret A. Carpenter, Max J. G. Appel, Melody E. Roelke-Parker, Linda Munson, Heribert Hofer, Marion East, Stephen J. O'Brien
Biology Faculty Articles

Influence of the CCR2-V64I Polymorphism on Human Immunodeficiency Virus Type 1 Coreceptor Activity and on Chemokine Receptor Function of CCR2b, CCR3, CCR5, and CXCR4, Benhur Lee, Benjamin J. Doranz, Shalini Rana, Yanji Yi, Mario Mellado, Jose M. R. Frade, Carlos Martinez-A., Stephen J. O'Brien, Michael Dean, Ronald G. Collman, Robert W. Doms
Biology Faculty Articles

Exclusive and Persistent Use of the Entry Coreceptor CXCR4 by Human Immunodeficiency Virus Type 1 from a Subject Homozygous for CCR5 Δ32, Nelson L. Michael, Julie A. E. Nelson, Vineet N. Kewalramani, George Chang, Stephen J. O'Brien, John R. Mascola, Barbara Volsky, Mark Louder, Gilbert C. White II, Dan R. Littman, Ronald Swanstrom, Thomas R. O'Brien
Biology Faculty Articles

Dating the Origin of the CCR5-Δ32 AIDS-Resistance Allele by the Coalescence of Haplotypes, J. Claiborne Stephens, David E. Riech, David B. Goldstein, Hyoung Doo Shin, Michael W. Smith, Mary Carrington, Cheryl Winkler, Gavin A. Huttley, Rando Allikmets, Lynn Schriml, Bernard Gerrard, Michael Malasky, Maria D. Ramos, Susanne Morlot, Maria Tzetis, Carole Oddoux, Francesco S. di Giovine, Georgios Nasioulas, David Chandler, Michael Aseev, Matthew Hanson, Luba Kalaydjieva, Damjan Glavac, Paolo Gasparini, E. Kanavakis, Mireille Claustres, Marios Kambouris, Harry Ostrer, Gordon Duff, Vladislav Baranov, Hiljar Sibul, Andres Metspalu, David Goldman, Nick Martin, David Duffy, Jorg Schmidtke, Xavier Estivill, Stephen J. O'Brien, Michael Dean
Biology Faculty Articles

Progression to AIDS, Sharyne Donfield, Henry S. Lynn, Margaret Hilgartner, Michael W. Smith, Michael Dean, Mary Carrington, Cheryl Winkler, Stephen J. O'Brien
Biology Faculty Articles

CCR2-64I Allele and Genotype Association with Delayed AIDS Progression in African Women, A. O. Anzala, T. B. Ball, T. Rostron, Stephen J. O'Brien, F. A. Plummer, S. L. Rowland-Jones, University of Nairobi Collaboration for HIV Research
Biology Faculty Articles

C-C Chemokines, Pivotal in Protection Against HIV Type 1 Infection, Daniel Zagury, Abderrahim Lachgar, Vida Chams, Lat S. Fall, Jacky Bernard, Jean-Francois Zagury, Bernard Bizzini, Allesandro Gringeri, Elena Santagostino, Jay Rappaport, Michael Feldman, Stephen J. O'Brien, Arsene Burny, Robert C. Gallo
Biology Faculty Articles

Genetic Restriction of AIDS Pathogenesis by an SDF-1 Chemokine Gene Variant, Cheryl Winkler, William Modi, Michael W. Smith, George W. Nelson, Xueyun Wu, Mary Carrington, Michael Dean, Tasaku Honjo, Kai Tashiro, D. Yabe, Susan Buchbinder, Eric Vittinghoff, James J. Goedert, Thomas R. O'Brien, Lisa Jacobson, Roger Detels, Sharyne Donfield, Anne Willoughby, Edward Gomperts, David Vlahov, John Phair, ALIVE Study, Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, Stephen J. O'Brien
Biology Faculty Articles

Novel Alleles of the Chemokine-Receptor Gene CCR5, Mary Carrington, Teri Kissner, Bernard Gerrard, Sergey Ivanov, Stephen J. O'Brien, Michael Dean
Biology Faculty Articles

CCR2 Chemokine Receptor and AIDS Progression, Michael W. Smith, Mary Carrington, Cheryl Winkler, Deborah A. Lomb, Michael Dean, Gavin A. Huttley, Stephen J. O'Brien
Biology Faculty Articles

Evolutionary Analysis of the 5'-Terminal Region of Hepatitis G Virus Isolated From Different Regions in China, Ping An, Li Wei, Xueyun Wu, Naoya Yuhki, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

In Search of AIDS-Resistance Genes, Stephen J. O'Brien, Michael Dean
Biology Faculty Articles

CCR5-Δ32 Gene Deletion in HIV-1 Infected Patients, Michael W. Smith, Michael Dean, Mary Carrington, Gavin A. Huttley, Stephen J. O'Brien
Biology Faculty Articles

Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression, Michael W. Smith, Michael Dean, Mary Carrington, Cheryl Winkler, Gavin A. Huttley, Deborah A. Lomb, James J. Goedert, Thomas R. O'Brien, Lisa Jacobson, Richard A. Kaslow, Susan Buchbinder, Eric Vittinghoff, David Vlahov, Keith Hoots, Margaret Hilgartner, Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study, Stephen J. O'Brien
Biology Faculty Articles

Growth of Lion and Puma Lentiviruses in Domestic Cat Cells and Comparisons with FIV, Sue VandeWoude, Stephen J. O'Brien, Ken Langelier, William D. Hardy, Jill P. Slattery, Evelyn E. Zuckerman, Edward A. Hoover
Biology Faculty Articles

The tax Gene Sequences Form Two Divergent Monophyletic Lineages Corresponding to Types I and II of Simian and Human T-Cell Leukemia/Lymphotropic Viruses, Adriana Giri, Jill Pecon-Slattery, Walid Heneine, Antoine Gessain, Emilia Rivadeneira, Ronald C. Desrosiers, Leon Rosen, Ronald Anthony, Joko Pamungkas, Diah Iskandriati, Allen L. Richards, Vincent Herve, Harold McClure, Stephen J. O'Brien, Genoveffa Franchini
Biology Faculty Articles

The HIV-AIDS Debate is Over, Stephen J. O'Brien
Biology Faculty Articles

Conservation of Human vs. Feline Genome Organization Revealed by Reciprocal Chromosome Painting, J. Weinberg, R. Stanyon, W. G. Nash, P. C. O'Brien, F. Yang, Stephen J. O'Brien, M. A. Ferguson-Smith
Biology Faculty Articles

Participants in HIV Study: Correction, Michael Dean, Mary Carrington, James J. Goedert, Stephen J. O'Brien
Biology Faculty Articles

HIV Causes AIDS: Koch's Postulates Fulfilled, Stephen J. O'Brien, James J. Goedert
Biology Faculty Articles

Prevalence of Antibodies to Feline Parvovirus, Calicivirus, Herpesvirus, Coronavirus, and Immunodeficiency Virus and of Feline Leukemia Virus Antigen and the Interrelationship of These Viral Infections in Free-Ranging Lions in East Africa, Regina Hofmann-Lehmann, Daniela Fehr, Markus Grob, Muhamed Elgizoli, Craig Packer, Janice S. Martenson, Stephen J. O'Brien, Hans Lutz
Biology Faculty Articles

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene, Michael Dean, Mary Carrington, Cheryl Winkler, Gavin A. Huttley, Michael W. Smith, Rando Allikmets, James J. Goedert, Susan Buchbinder, Eric Vittinghoff, Edward Gomperts, Sharyne Donfield, David Vlahov, Richard A. Kaslow, A. J. Saah, Charles Rinaldo, Roger Detels, Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, Stephen J. O'Brien
Biology Faculty Articles

Serum Antibody to Rift Valley Fever Virus in African Carnivores, Carol House, Kathleen A. Alexander, Pieter W. Kat, Stephen J. O'Brien, Joseph Mangiafico
Biology Faculty Articles

Influence of Combinations of Human Major Histocompatibility Complex Genes on the Course of HIV−1 Infection, Richard A. Kaslow, Mary Carrington, R. Apple, L. Park, A. Muñoz, A. J. Saah, James J. Goedert, Cheryl Winkler, Stephen J. O'Brien, Charles Rinaldo, Roger Detels, W. Blattner, John Phair, H. Erlich, Dean L. Mann
Biology Faculty Articles

Report of the Fifth International Workshop on Human Chromosome 11 Mapping 1996, T. B. Shows, M. Alders, S. Bennett, D. Burbee, P. Cartwright, S. Chandrasekharappa, P. Cooper, A. Courseaux, C. Davies, M. D. Devignes, P. Devilee, R. Elliott, G. Evans, J. Fantes, H. Garner, P. Gaudray, D. S. Gerhard, M. Gessler, M. Higgins, H. Hummerich, M. James, J. Lagercrantz, M. Litt, P. Little, M. Mannens, D. Munroe, N. Nowak, Stephen J. O'Brien, N. Parker, M. Perlin, L. Reid, C. Richard, M. Sawicki, D. Swallow, R. Thakker, E. van Heyningen, I. Vorechovsky, C. Wadelius, B. Weber, B. Zabel
Biology Faculty Articles

Genome Evolution Comes of Age, Daniel L. Hartl, Fotis C. Kafatos, Stephen J. O'Brien
Biology Faculty Articles

African Horse Sickness and African Carnivores, K. A. Alexander, P. W. Kat, Carol House, Stephen J. O'Brien, M. Karen Laurenson, J. Weldon McNutt, Bennie I. Osburn
Biology Faculty Articles

Genomic Prospecting, Stephen J. O'Brien
Biology Faculty Articles

Assignment of Islet Amyloid Polypeptide (IAPP) Gene to Feline Chromosome B4 Using the Polymerase Chain Reaction Technique on Feline-Rodent Hybrid Cell Lines, K. Jordan, Stephen J. O'Brien, K. H. Johnson, T. D. O'Brien
Biology Faculty Articles

Polymorphic Admixture Typing in Human Ethnic Populations, Michael Dean, J. Claiborne Stephens, Cheryl Winkler, Deborah A. Lomb, Mark Ramsburg, Raleigh Boaze, Claudia Stewart, Lauren Charbonneau, David Goldman, Bernard J. Albaugh, James J. Goedert, R. Palmer Beasley, Lu-Yu Hwang, Susan Buchbinder, Michael Weedon, Patricia A. Johnson, Mary Eichelberger, Stephen J. O'Brien
Biology Faculty Articles

Mapping by Admixture Linkage Disequilibrium in Human Populations: Limits and Guidelines, J. Claiborne Stephens, D. Briscoe, Stephen J. O'Brien
Biology Faculty Articles

Polymorphisms in the 3′ Untranslated Region of the IκB/MAD-3 (NFKBI) Gene Located on Chromosome 14, Damjan Glavac, Metka Ravnik-Glavac, Stephen J. O'Brien, Michael Dean
Biology Faculty Articles

Phylogenetic Associations of Human and Simian T-Cell Leukemia/Lymphotropic Virus Type I Strains: Evidence for Interspecies Transmission, Igor J. Koralnik, Enzo Boeri, W. Carl Saxinger, Anita Lo Monico, Jake Fullen, Antoine Gessain, Hong-Guang Guo, Robert C. Gallo, Phillip Markham, Vaniambadi Kalyanaraman, Vanessa Hirsch, Jonathan Allan, Krishna Murthy, Patricia Alford, Jill Pecon-Slattery, Stephen J. O'Brien, Genoveffa Ranchini
Biology Faculty Articles

Linkage Disequilibrium in Admixed Populations: Applications in Gene Mapping, D. Briscoe, J. Claiborne Stephens, Stephen J. O'Brien
Biology Faculty Articles

Genomes and Evolution - Editorial Overview, Stephen J. O'Brien, Michael T. Clegg
Biology Faculty Articles

Chromosomal Mapping of Two Members of the Human Glutamate Dehydrogenase (GLUD) Gene Family to Chromosomes 10q22.3-q23 and Xq22-q23, Nicholas P. Anagnou, H. N. Seuanez, W. S. Modi, Stephen J. O'Brien, J. Papamatheakis, N. K. Moschonas
Biology Faculty Articles

The Genomics Generation, Stephen J. O'Brien
Biology Faculty Articles

Estimation of Heterozygosity for Single-Probe Multilocus DNA Fingerprints, J. Claiborne Stephens, Dennis Gilbert, Naoya Yuhki, Stephen J. O'Brien
Biology Faculty Articles

Adaptive Chaos and AIDS, Stephen J. O'Brien, Dean L. Mann
Biology Faculty Articles

Detecting Single Base Substitutions as Heteroduplex Polymorphisms, Marga Belle White, Magda Carvalho, David Derse, Stephen J. O'Brien, Michael Dean
Biology Faculty Articles

BEK, a Receptor for Multiple Members of the Fibroblast Growth Factor (FGF) Family, Maps to Human Chromosome 10q25.3----q26, C. A. Dionne, W. S. Modi, G. Crumley, Stephen J. O'Brien, J. Schlessinger, M. Jaye
Biology Faculty Articles

Linkage Mapping of Human Polymorphic Proteins Identified by Two-Dimensional Electrophoresis, David Goldman, Stephen J. O'Brien, Susan Lucas-Derse, Michael Dean
Biology Faculty Articles

Mapping of the Gene Encoding the α Subunit of the Stimulatory G Protein of Adenylyl Cyclase (GNAS1) to 20q13.2 → q13.3 in Human by In Situ Hybridization, Michael A. Levine, William Modi, Stephen J. O'Brien
Biology Faculty Articles

Genetic Mapping of the β1 GABA Receptor Gene to Human Chromosome 4, Using a Tetranucleotide Repeat Polymorphism, Michael Dean, Susan Lucas-Derse, Annabel Bolos, Stephen J. O'Brien, Ewen F. Kirkness, Claire M. Fraser, David Goldman
Biology Faculty Articles

Ghetto Legacy: Can the High Incidence of Tay-Sachs Disease in Ashkenazi Jews be Linked to Historic Epidemics of Tuberculosis in Industrial European Cities?, Stephen J. O'Brien
Biology Faculty Articles

Detecting High-Resolution Polymorphisms in Human Coding Loci by Combining PCR and Single-Strand Conformation Polymorphism (SSCP) Analysis, Shirley E. Poduslo, Michael Dean, Ulricke Kolch, Stephen J. O'Brien
Biology Faculty Articles

Linkage Mapping of the Human CSF2 and IL3 Genes, Elena I. Frolova, Gregory M. Dolganov, Ilya A. Mazo, Dmitzy V. Smirnov, Paul Copeland, Stephen J. O'Brien, Michael Dean
Biology Faculty Articles

Report of the Committee on Comparative Gene Mapping, Stephen J. O'Brien, J. A. M. Graves
Biology Faculty Articles

Developmental Changes in Pituitary–Gonadal Function in Free-Ranging Lions (Panthera leo leo) of the Serengeti Plains and Ngorongoro Crater, J. L. Brown, Mitch E. Bush, Craig Packer, A. E. Pusey, S. L. Monfort, Stephen J. O'Brien, D. L. Janssen, David E. Wildt
Biology Faculty Articles

Dissociative Anaesthesia in Free-Ranging Male Koalas and Selected Marsupials in Captivity, Mitch E. Bush, J. A. M. Graves, Stephen J. O'Brien, David E. Wildt
Biology Faculty Articles

Chromosomal Localization of the Genes Encoding Two Forms of the G Protein β Polypeptide, β1 and β3, in Man, Michael A. Levine, William Modi, Stephen J. O'Brien
Biology Faculty Articles

Sequence and Chromosomal Location of the I-309 Gene. Relationship to Genes Encoding a Family of Inflammatory Cytokines, Michael D. Miller, Stephen D. Wilson, Martin E. Dorf, Hector Seuanez, Stephen J. O'Brien, Michael S. Krangel
Biology Faculty Articles

Application of DNA Fingerprints for Cell-Line Individualization, Dennis A. Gilbert, Yvonne Reid, Mitchell H. Gail, David Pee, Christine White, Robert J. Hay, Stephen J. O'Brien
Biology Faculty Articles

An Oncogenic Chromosome 8-9 Gene Fusion Isolated Following Transfection of Human Ovarian Carcinoma Cell Line DNA, D. Halverson, W. S. Modi, M. Dean, E. P. Gelmann, K. J. Dunn, D. Clanton, M. Oskarsson, Stephen J. O'Brien, D. G. Blair
Biology Faculty Articles

Chromosome Assignment by Polymerase Chain Reaction Techniques: Assignment of the Oncogene FGF-5 to Human Chromosome 4, C. A. Dionne, R. Kaplan, H. N. Seuanez, Stephen J. O'Brien, M. Jaye
Biology Faculty Articles

Report of the Committee on Comparative Gene Mapping, Stephen J. O'Brien, J. A. Graves
Biology Faculty Articles

Monocyte-Derived Neutrophil Chemotactic Factor (MDNCF/IL-8) Resides in a Gene Cluster along with Several Other Members of the Platelet Factor 4 Gene Superfamily, William Modi, Michael Dean, Hector Seuanez, Naofumi Mukaida, Kouji Matsushima, Stephen J. O'Brien
Biology Faculty Articles

The Human Chromogranin A Gene: Chromosome Assignment and RFLP Analysis., William Modi, Michael A. Levine, Hector Seuanez, Michael Dean, Stephen J. O'Brien
Biology Faculty Articles

Cloning and Comparative Mapping of a Human Class III (X) Alcohol Dehydrogenase cDNA, P. Rathna Giri, Jane F. Krug, Christine Kozak, Tamyra Moretti, Stephen J. O'Brien, Hector Seuanez, David Goldman
Biology Faculty Articles

Mapping of PRM 1 to Human Chromosome 16 and Tight Linkage of Prm-1 and Prm-2 on Mouse Chromosome 16, Roger Reeves, John Gearhart, N. B. Hecht, P. Yelick, P. Johnson, Stephen J. O'Brien
Biology Faculty Articles

A Glutaminase (Gls) Gene Maps to Mouse Chromosome 1, Rat Chromosome 9, and Human Chromosome 2, Beverly Mock, Christine Kozak, Michael F. Seldin, Naomi Ruff, Lawrence D'Hoostelaere, Claude Szpirer, Hector Seuanez, Stephen J. O'Brien, Carl Banner
Biology Faculty Articles

The Human Homolog of the Moloney Leukemia Virus Integration 2 Locus (MLVI2) Maps to Band p14 of Chromosome 5, Nicholas P. Anagnou, Agathe Economou-Pachnis, Stephen J. O'Brien, William S. Modi, Arthur W. Nienhuis, Philip N. Tsichlis
Biology Faculty Articles

Chromosomal Localization of Nucleic Acid-Binding Proteins by Affinity Mapping: Assignment of the IRE-Binding Protein Gene to Human Chromosome 9, Matthias W. Hentze, Hector Seuanez, Stephen J. O'Brien, Joe B. Harford, Richard D. Klausner
Biology Faculty Articles

Origin of the HIV-Susceptible Human CD4+ Cell Line H9, Dean L. Mann, Stephen J. O'Brien, Dennis A. Gilbert, Yvonne Reid, Mikulas Popovic, Elizabeth Read-Connole, Robert C. Gallo, Adi F. Gazdar
Biology Faculty Articles

Comparative Features of a Coronavirus Isolated from a Cheetah with Feline Infectious Peritonitis, J. F. Evermann, J. L. Heeney, A. J. McKeirnan, Stephen J. O'Brien
Biology Faculty Articles

The t(11;14)(p15;q11) in a T-Cell Acute Lymphoblastic Leukemia Cell Line Activates Multiple Transcripts, Including Ttg-1, a Gene Encoding a Potential Zinc Finger Protein, Elizabeth A. McGuire, Richard D. Hockett, Karen M. Pollock, Marty F. Bartholdi, Stephen J. O'Brien, Stanley J. Korsmeyer
Biology Faculty Articles

Genetic Characterization of FLA, the Cat Major Histocompatibility Complex, Cheryl Winkler, Alan Schultz, Stephen J. O'Brien
Biology Faculty Articles

The Human Endonexin II (ENX2) Gene Is Located at 4q28----q32, William Modi, H. N. Seuanez, M. Jaye, H. J. Haigler, R. Kaplan, Stephen J. O'Brien
Biology Faculty Articles

Report of the Committee on Comparative Mapping, P. A. Lalley, M. T. Davisson, J. A. Graves, Stephen J. O'Brien, J. E. Womack, T. H. Roderick, N. Creau-Goldberg, A. L. Hillyard, D. P. Doolittle, J. A. Rogers
Biology Faculty Articles

Molecular Analysis of the Human Serum Amyloid a (SAA) Gene Family, G. H. Sack Jr., C. C. Talbot Jr., Hector Seuanez, Stephen J. O'Brien
Biology Faculty Articles

Molecular Cloning and Chromosomal Localization of the Human T-Cell Receptor ζ Chain: Distinction from the Molecular CD3 Complex, Allan M. Weissman, Damon Hou, David G. Orloff, William S. Modi, Hector Seuanez, Stephen J. O'Brien, Richard D. Klausner
Biology Faculty Articles

The Human erg Gene Maps to Chromosome 21, Band q22: Relationship to the 8; 21 Translocation of Acute Myelogenous Leukemia, V. N. Rao, W. S. Modi, H. D. Drabkin, D. Patterson, Stephen J. O'Brien, T. S. Papas, E. S. Reddy
Biology Faculty Articles

The GLI-Kruppel Family of Human Genes, John M. Ruppert, Kenneth W. Kinzler, Albert J. Wong, Sandra H. Bigner, Fa-Ten Kao, Martha L. Law, Hector Seuanez, Stephen J. O'Brien, Bert Vogelstein
Biology Faculty Articles

Chromosomal Localization of the Human Interleukin 1α (IL-1α) Gene, William Modi, Akinori Masuda, Masaaki Yamada, Joost J. Oppenheim, Kouji Matsushima, Stephen J. O'Brien
Biology Faculty Articles

The κ-Deleting Element: Germline and Rearranged, Duplicated and Dispersed Forms, Winfried B. Graninger, Paula L. Goldman, Cynthia C. Morton, Stephen J. O'Brien, Stanley J. Korsmeyer
Biology Faculty Articles

Report of the Committee on Comparative Mapping, P. A. Lalley, M. T. Davisson, J. A. Graves, Stephen J. O'Brien, T. H. Roderick, D. P. Doolittle, A. L. Hillyard
Biology Faculty Articles

Chromosomal Localization and Racial Distribution of the Polymorphic Human Dihydrofolate Reductase Pseudogene (DHFRP1), Nicholas P. Anagnou, S. E. Antonarakis, Stephen J. O'Brien, William S. Modi, Arthur W. Nienhuis
Biology Faculty Articles

Partial Structure of the Human α2(IV) Collagen Chain and Chromosomal Localization of the Gene (COL4A2), Paul D. Killen, Clair A. Francomano, Yoshihiko Yamada, William Modi, Stephen J. O'Brien
Biology Faculty Articles

Isolation of a cDNA Clone for the Human Laminin-B1 Chain and its Gene Localization, Michael Jaye, William Modi, George A. Ricca, Robert Mudd, Inc-Ming Chiu, Stephen J. O'Brien, William N. Drohan
Biology Faculty Articles

Molecular Analysis of Integrated Human Papillomavirus 16 Sequences in the Cervical Cancer Cell Line SiHa, Mostafa K. El Awady, Jeffrey B. Kaplan, Stephen J. O'Brien, Robert D. Burk
Biology Faculty Articles

The Interleukin 3 Gene is Located on Human Chromosome 5 and is Deleted in Myeloid Leukemias with a Deletion of 5q, MIchelle M. LeBeau, Neal D. Epstein, Stephen J. O'Brien, Arthur W. Nienhuis, Yu-Chung Yang, Steven C. Clark, Janet D. Rowley
Biology Faculty Articles

A Novel Form of Human Polymorphism Involving the hDHFR-ψ1 Pseudogene Identifies Three RFLPs, Nicholas P. Anagnou, S. E. Antonarakis, Stephen J. O'Brien, Arthur W. Nienhuis
Biology Faculty Articles

The Human Myelin-Basic-Protein Gene: Chromosomal Localization and RFLP Analysis, John Kamholz, Richard Spielman, William Modi, Stephen J. O'Brien, Robert Lazzarini
Biology Faculty Articles

Identification of an Amplified, Highly Expressed Gene in a Human Glioma, Kenneth W. Kinzler, Sandra H. Bigner, Darrell D. Bigner, Jeffrey M. Trent, Martha L. Law, Stephen J. O'Brien, Albert J. Wong, Bert Vogelstein
Biology Faculty Articles

Genetic Characterization of Human c-rel Sequences, Elise Brownell, Stephen J. O'Brien, William Nash, Nancy Rice
Biology Faculty Articles

Cloning, Characterization, Expression, and Chromosomal Localization of a Human Ferritin Heavy-Chain Gene, Matthias W. Hentze, Stephen Keim, Panos Papadopoulos, Stephen J. O'Brien, William Modi, Jim Drysdale, William J. Leonard, Joe B. Harford, Richard D. Klausner
Biology Faculty Articles

Dynamic and Nonspecific Dispersal of Human T-Cell Leukemia/Lymphoma Virus Type-I Integration in Cultured Lymphoma Cells, Leonard J. Seigel, William G. Nash, Bernard J. Poiesz, Janet L. Moore, Stephen J. O'Brien
Biology Faculty Articles

Comparative Genetic Mapping of Cellular rel Sequences in Man, Mouse, and the Domestic Cat, Elise Brownell, Christine Kozak, John R. Fowle III, William Modi, Nancy Rice, Stephen J. O'Brien
Biology Faculty Articles

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization, Michael Jaye, Richard Howk, Wilson Burgess, George A. Ricca, Ing-Ming Chiu, Mark W. Ravera, Stephen J. O'Brien, William Modi, Thomas Maciag, William N. Drohan
Biology Faculty Articles

The Cellular ets Genes: Molecular Biology and Clinical Implications in Human Leukemias, T. S. Papas, D. K. Watson, N. Sacchi, Stephen J. O'Brien, R. Ascione
Biology Faculty Articles

Molecular Evolution of ets Genes from Avians to Mammals and Their Cytogenetic Localization to Regions Involved in Leukemia, T. S. Papas, D. K. Watson, N. Sacchi, Stephen J. O'Brien, R. Ascione
Biology Faculty Articles

Tetraploid Partial Hydatidiform Moles: Two Cases with a Triple Paternal Contribution and a 92,XXXY Karyotype, U. Surti, A. E. Szulman, K. Wagner, M. Leppert, Stephen J. O'Brien
Biology Faculty Articles

Transactivation Induced by Human T-Lymphotropic Virus Type III (HTLV III) Maps to a Viral Sequence Encoding 58 Amino Acids and Lacks Tissue Specificity, Leonard J. Seigel, Lee Ratner, Steven F. Josephs, David Dersefi, Mark B. Feinberg, Gregory R. Reyes, Stephen J. O'Brien, Flossie Wong-Staal
Biology Faculty Articles

Expression of the Human C-Fms Proto-Oncogene in Hematopoietic Cells and its Deletion in the 5q− Syndrome, Arthur W. Nienhuis, H. Franklin Bunn, Patricia H. Turner, T. Venkat Gopal, William Nash, Stephen J. O'Brien, Charles J. Sherr
Biology Faculty Articles

Twenty-Seven Protein Polymorphisms by Two-Dimensional Electrophoresis of Serum, Erythrocytes, and Fibroblasts in Two Pedigrees, David Goldman, Lynn R. Goldin, P. Rathnagiri, Stephen J. O'Brien, Janice A. Egeland, Carl R. Merril
Biology Faculty Articles

Organization and Chromosomal Specificity of Autosomal Homologs of Human Y Chromosome Repeated DNA, Robert D. Burk, Paul Szabo, Stephen J. O'Brien, William G. Nash, Lohchung Yu, Kirby D. Smith
Biology Faculty Articles

ERV3, a Full-Length Human Endogenous Provirus: Chromosomal Localization and Evolutionary Relationships, Cathy O'Connell, Stephen J. O'Brien, William G. Nash, Maurice Cohen
Biology Faculty Articles

Isolation of HTLV-Transformed B-Lymphocyte Clone from a Patient with HTLV-Associated Adult T-Cell Leukaemia, Dan L. Longo, Edward P. Gelmann, Jeffrey Cossman, Rebecca A. Young, Robert C. Gallo, Stephen J. O'Brien, Louis A. Matis
Biology Faculty Articles

The Human Homologs of the raf (mil) Oncogene are Located on Human Chromosomes 3 and 4, Tom I. Bonner, Stephen J. O'Brien, William Nash, Ulf R. Rapp, Cynthia C. Morton, Philip Leder
Biology Faculty Articles

Gene for T-Cell Growth Factor: Location on Human Chromosome 4q and Feline Chromosome B1, Leonard J. Seigel, Mary E. Harper, Flossie Wong-Staal, Robert C. Gallo, William Nash, Stephen J. O'Brien
Biology Faculty Articles

Clonal Variation of MCF-7 Breast Cancer Cells In Vitro and in Athymic Nude Mice, Katherine Seibert, Samir M. Shafie, Timothy J. Triche, Jacqueline J. Whang-Peng, Stephen J. O'Brien, Jeffrey H. Toney, Karen K. Huff, Marc E. Lippman
Biology Faculty Articles

Mapping of an Endogenous Retroviral Sequence to Human Chromosome 18, Stephen J. O'Brien, Tom I. Bonner, Maurice Cohen, Cathy O'Connell, William Nash
Biology Faculty Articles

Dispersion of the ras Family of Transforming Genes to Four Different Chromosomes in Man, Stephen J. O'Brien, William G. Nash, Jerome L. Goodwin, Douglas R. Lowy, Esther H. Chang
Biology Faculty Articles

Parallels of Genomic Organization and of Endogenous Retrovirus Organization in Cat and Man, Stephen J. O'Brien, Roger Reeves, Janice M. Simonson, Mary Eichelberger, William G. Nash
Biology Faculty Articles

Owl Monkey Cell Line, Stephen J. O'Brien
Biology Faculty Articles

Contamination of Hodgkin's Disease Cell Cultures, Nancy L. Harris, David L. Gang, Steven C. Quay, Sibrand Poppema, Paul C. Zamecnik, Walter A. Nelson-Rees, Stephen J. O'Brien
Biology Faculty Articles

Genetic Diversity in Leukemia-Prone Feral House Mice Infected with Murine Leukemia Virus, Catherine Rice, Murray B. Gardner, Stephen J. O'Brien
Biology Faculty Articles

A Molecular Approach to the Identification and Individualization of Human and Animal Cells in Culture: Isozyme and Allozyme Genetic Signatures, Stephen J. O'Brien, John E. Shannon, Mitchell H. Gail
Biology Faculty Articles

Characteristics of HeLa Strains: Permanent vs. Variable Features, W. A. Nelson-Rees, L. Hunter, G. J. Darlington, Stephen J. O'Brien
Biology Faculty Articles

Complete (Classic) Hydatidiform Mole with 46,XY Karyotype of Paternal Origin, U. Surti, A. E. Szulman, Stephen J. O'Brien
Biology Faculty Articles

Characterization of WiDr: A Human Colon Carcinoma Cell Line, P. Noguchi, R. Wallace, J. Johnson, E. M. Earley, Stephen J. O'Brien, S. Ferrone, M. A. Pellegrino, J. Milstien, C. Needy, W. Browne, J. Petricciani
Biology Faculty Articles

Genetic Aspects of Carcinogenesis and Carcinogen Testing, Stephen J. O'Brien, Catherine Rice
Biology Faculty Articles

Establishment and Characterization of Three New Continuous Cell Lines Derived from Human Breast Carcinomas, Linda W. Engel, Nathaniel A. Young, Tommie Sue Tralka, Marc E. Lippman, Stephen J. O'Brien, Mary Jo Joyce
Biology Faculty Articles

A Gene (Bevi) on Human Chromosome 6 Is an Integration Site for Baboon Type C DNA Provirus in Human Cells, Richard S. Lemons, William G. Nash, Stephen J. O'Brien, Raoul E. Benveniste, Charles J. Sherr
Biology Faculty Articles

On the “Lucke Tumor” Origin of Cell Line LT-1: Reply, Louis S. Kucera, Janice Simonson, Stephen J. O'Brien, Hayden Coon
Biology Faculty Articles

The Bevi Locus (Chromosome 6) Encodes a Post-Penetrational Cellular Function Required for Baboon Endogenous Virus Replication in Human Cells, R. S. Lemons, Stephen J. O'Brien, C. J. Sherr
Biology Faculty Articles

A New Genetic Locus, Bevi, on Human Chromosome 6 Which Controls the Replication of Baboon Type C Virus in Human Cells, Richard S. Lemons, Stephen J. O'Brien, Charles J. Sherr
Biology Faculty Articles

Enzyme Polymorphisms as Genetic Signatures in Human Cell Cultures, Stephen J. O'Brien, Gail Kleiner, Russell Olson, John E. Shannon
Biology Faculty Articles