Comparing Outcomes of Appendectomy Versus Non-operative Antibiotic Therapy for Acute Appendicitis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Israel Zagales, Matthew Sauder, Sruthi Selvakumar, Jeffrey Spardy, Radleigh Santos, Jozef Cruz, Tracy Bilski, Adel Elkbuli
Mathematics Faculty Articles

The Relationship Between COVID-19 Infection Rates and Social Determinants of Health in Broward and Miami-Dade Counties, Florida, Lindsey A. Taylor, Jarrod Sheehan, Ariel T. Paz, Monica Tromer, Erica Pieper, Iman Squires, Aysha Nuhuman, Radleigh Santos, Robin Jacobs
Mathematics Faculty Articles

Disparities in Adult and Pediatric Trauma Outcomes: a Systematic Review and Meta-Analysis, Carol Sanchez, Saamia Shaikh, Brianna Dowd, Radleigh Santos, Mark McKenney, Adel Elkbuli
Radleigh Santos

Disparities in Adult and Pediatric Trauma Outcomes: a Systematic Review and Meta-Analysis, Carol Sanchez, Saamia Shaikh, Brianna Dowd, Radleigh Santos, Mark McKenney, Adel Elkbuli
Mathematics Faculty Articles

Biscyclic guanidine compound compositions, methods of use and treatment thereof, Lindsey Shaw, Renee Fleeman, Richard A. Houghten, Marc Giulianotti, Radleigh Santos, Adel Nefzi
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Melanocortin Ligands and Methods of Use Thereof, Carrie Haskell-Luevano, Skye R. Doering, Jon R. Appel, Marc Giulianotti, Richard A. Houghten, Clemencia Pinilla, Radleigh Santos
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

BIS-cyclic guanidine compound compositions, methods of use and treatment thereof, Lindsey Neil Shaw, Renee Fleeman, Richard A. Houghten, Marc Giulianotti, Radleigh Santos, Adel Nefzi
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Calcium Transient Assays for Compound Screening with Human iPSC-derived Cardiomyocytes: Evaluating New Tools, Neil J. Daily, Radleigh Santos, Joseph Vecchi, Pinar Kemanli, Tetsuro Wakatsuki
Mathematics Faculty Articles

Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrate, Franck Madoux, Daniela Dreymuller, Jean-Phillipe Pettiloud, Radleigh Santos, Christoph Becker-Pauly, Andreas Ludwig, Gregg B. Fields, Thomas Bannister, Timothy P. Spicer, Mare Cudic, Louis D. Scampavia, Dmitriy Minond
Mathematics Faculty Articles

Categorizing immune responders with fusion metrics and simulation for association to survival & progression free survival with immune response in HLA-A2+ patients with GBM from a phase 2 trial of dendritic cell (DC) immunotherapy (ICT-107)., Radleigh Santos, Clemencia Pinilla, Steve J. Swanson, Anthony Gringeri, John Yu
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Using Fusion of Response Metrics and Monte Carlo Simulation to Determine Immune Response in Cancer Immunotherapy Patients, Radleigh Santos, Alcinette Bunying, Nazila Sabri, John Yu, Steve J. Swanson, Valeria A. Judkowski, Pedro Romero, Sylvia Janetzki, Clemencia Pinilla
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library, Laura D. Hamel, Brian J. Lenhart, David A. Mitchell, Radleigh Santos, Marc A. Giulianotti, Robert J. Deschenes
Mathematics Faculty Articles

Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734 821 Pyrrolidine Bis-piperazines, Richard A. Houghten, Michelle L. Ganno, Jay P. McLaughlin, Colette T. Dooley, Shainnel O. Eans Torrey Pines Institute for Molecular Studies, Radleigh Santos, Travis LaVoi, Adel Nefzi, Greg Welmaker, Marc A. Giulianotti, Lawrence Toll
Mathematics Faculty Articles

Association of Survival and Progression-Free Survival with Immune Response in HLA-A2+ Newly- Diagnosed GBM Patients in Randomized Double-Blind Placebo-Controlled Phase 2 Trial of Dentritic Cell (DC) Immunotherapy with ICT-107, Patrick Wen, David Reardon, Surasak Phuphanich, Robert Aiken, Joseph Landolfi, William Curry, Jay-Jiguang Zhu, Michael Glantz, David Peereboom, James Markert, Renato Larocca, Donald O'Rourke, Karen Fink, Lyndon Kim, Michael Gruber, Glenn Lesser, Ed Pan, Radleigh Santos, Clemencia Pinilla, John Yu
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Statistically significant association of glioblastoma immunotherapy phase II clinical study (ICT-107) treatment and survival to immune response using a novel comprehensive ELISPOT analysis., Radleigh Santos, Anthony Gringeri, John Yu, Sylvia Janetzki, Valeria A. Judkowski, Clemencia Pinilla
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Investigating the Role of the Host Multidrug Resistance Associated Protein Transporter Family in Burkholderia cepacia Complex Pathogenicity Using a Caenorhabditis elegans Infection Model, Pietro Tedesco, Marco Visone, Ermenegilda Parrilli, Maria Luisa Tutino, Elena Perrin, Isabel Maida, Renato Fani, Francesco Ballestriero, Radleigh Santos, Clemencia Pinilla, Elia Di Schiavi, George Tegos, Donatella de Pascale
Mathematics Faculty Articles

Antigen Discovery for the Identification of Vaccine Candidates and Biomarkers Using a T Cell Driven Approach in Combination with Positional Scanning Peptide Libraries, Valeria A. Judkowski, Radleigh Santos, Gonzalo R. Acevedo, Marc Giulianotti, Jon R. Appel, Silvia A. Longhi, Karina A. Gomez, Clemencia Pinilla
Mathematics Faculty Articles

Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities, Miao Hu, Marc Giulianotti, Jay P. McLaughlin, Jiaan Shao, Ginamarie Debevec, Laura E. Maida, Phaedra Geer, Margaret Cazares, Jaime Misler, Ling Li, Colette T. Dooley, Michelle L. Ganno, Shainnel O. Eans Torrey Pines Institute for Molecular Studies, Elisa Mizrachi, Radleigh Santos, Austin B. Yongye, Richard A. Houghten, Yongping Yu
Mathematics Faculty Articles

Combinatorial Libraries As a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens, Renee Fleeman, Travis LaVoi, Radleigh Santos, Angela Morales, Adel Nefzi, Greg Welmaker, Jose L. Medina-Franco, Marc Giulianotti, Richard A. Houghten, Lindsey N. Shaw
Mathematics Faculty Articles

Improvement of IFNg ELISPOT Performance Following Overnight Resting of Frozen PBMC Samples Confirmed Through Rigorous Statistical Analysis, Radleigh Santos, Alcinette Bunying, Nazila Sabri, John Yu, Anthony Gringeri, James Bender, Sylvia Janetzki, Clemencia Pinilla, Valeria A. Judkowski
Mathematics Faculty Articles

Cytokine Production but Lack of Proliferation in Peripheral Blood Mononuclear Cells from Chronic Chagas' Disease Cardiomyopathy Patients in Response to T. cruzi Ribosomal P Proteins, Silvia A. Longhi, Augusto Atienza, Graciela Perez Prados, Alcinette Buying, Virginia Balouz, Carlos A. Buscaglia, Radleigh Santos, Laura M. Tasso, Ricardo Bonato, Pablo Chiale, Clemencia Pinilla, Valeria A. Judkowski, Karina A. Gomez
Mathematics Faculty Articles

Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin-4 Polymorphic Receptors (hMC4Rs), Erica M. Haslach, Huisuo Huang, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh Santos, Marc Giulianotti, Clemencia Pinilla, Jon R. Appel, Skye R. Doering, Michael A. Walters, Richard A. Houghten, Carrie Haskell-Luevano
Mathematics Faculty Articles

GM-CSF Production Allows the Identification of Immunoprevalent Antigens Recognized by Human CD4+ T Cells Following Smallpox Vaccination, Valeria A. Judkowski, Alcinette Bunying, Feng Ge, Jon R. Appel, Kingyee Law, Atima Sharma, Claudia Raja-Gabaglia, Patricia Norori, Radleigh Santos, Marc Giulianotti, Mark K. Slifka, Daniel C. Douek, Barney S. Graham, Clemencia Pinilla
Mathematics Faculty Articles

Structure–activity relationships of benzimidazole derivatives as antiparasitic agents: Dual activity-difference (DAD) maps, Jaime Perez-Villanueva, Radleigh Santos, Alicia Hernandez-Campos, Marc Giulianotti, Rafael Castillo, Jose L. Medina-Franco
Mathematics Faculty Articles