A Population-Based Study to Investigate Host Genetic Factors Associated with Hepatitis B Infection and Pathogenesis in the Chinese Population, Zheng Zheng, Li Guan, Ping An, Shan Sun, Stephen J. O'Brien, Cheryl Winkler
Stephen O'Brien

Genome-Wide and Differential Proteomic Analysis of Hepatitis B Virus and Aflatoxin B1 Related Hepatocellular Carcinoma in Guangxi, China, Lu-Nan Qi, Le-Qun Qi, Yuan-Yuan Chen, Zhao-Hong Chen, Tao Bai, Bang-De Xiang, Xiao Qin, Kai-Yin Xiao, Min-Hao Peng, Zhi-Ming Liu, Tang-Wei Liu, Xue Qin, Shan Li, Ze-Guang Han, Zeng-Nan Mo, Regina M. Santella, Cheryl Winkler, Stephen J. O'Brien, Tao Peng
Stephen O'Brien

Polymorphisms of CUL5 are Associated with CD4+ T Cell Loss in HIV-1 Infected Individuals, Ping An, Priya Duggal, Li Hua Wang, Stephen J. O'Brien, Sharyne Donfield, James J. Goedert, John Phair, Susan Buchbinder, Gregory D. Kirk, Cheryl Winkler
Stephen O'Brien

Regulatory Polymorphisms in the Cyclophilin A Gene, PPIA, Accelerate Progression to AIDS, Ping An, Li Hua Wang, Holli Hutcheson-Dilks, George Nelson, Sharyne Donfield, James J. Goedert, Charles Rinaldo, Susan Buchbinder, Gregory D. Kirk, Stephen J. O'Brien, Cheryl Winkler
Stephen O'Brien

Role of Exonic Variation in Chemokine Receptor Genes on AIDS: CCRL2 F167Y Association with Pneumocystis Pneumonia, Ping An, Rongling Li, Ji Ming Wang, Teizo Yoshimura, Munehisa Takahashi, Ram Samudralal, Stephen J. O'Brien, John Phair, James J. Goedert, Gregory D. Kirk, Jennifer L. Troyer, Efe Sezgin, Susan Buchbinder, Sharyne Donfield, George W. Nelson, Cheryl Winkler
Stephen O'Brien

Genome-Wide and Differential Proteomic Analysis of Hepatitis B Virus and Aflatoxin B1 Related Hepatocellular Carcinoma in Guangxi, China, Lu-Nan Qi, Le-Qun Qi, Yuan-Yuan Chen, Zhao-Hong Chen, Tao Bai, Bang-De Xiang, Xiao Qin, Kai-Yin Xiao, Min-Hao Peng, Zhi-Ming Liu, Tang-Wei Liu, Xue Qin, Shan Li, Ze-Guang Han, Zeng-Nan Mo, Regina M. Santella, Cheryl Winkler, Stephen J. O'Brien, Tao Peng
Biology Faculty Articles

Association Study of Common Genetic Variants and HIV- 1 Acquisition in 6,300 Infected Cases and 7,200 Controls, Paul J. McLaren, Cedric Coulonges, Stephan Ripke, Leonard H. van den Berg, Susan Buchbinder, Mary Carrington, Andrea Cossarizza, Judith Dalmau, Steven G. Deeks, Olivier Delaneau, Andrea De Luca, James J. Goedert, David W. Haas, Joshua T. Herbeck, Sekar Kathiresan, Gregory D. Kirk, Olivier Lambotte, Ma Luo, Simon Mallal, Danielle van Manen, Javier Martinez-Picado, Florencia Pereyra, Francis A. Plummer, Guido Poli, Ying Qi, Pierre Rucart, Manj S. Sandhu, Patrick R. Shea, Hanneke Schuitemaker, Ioannis Theodorou, Fredrik Vannberg, Jan Veldink, Bruce D. Walker, Amy C. Weintrob, Cheryl Winkler, Steven M. Wolinsky, Amalio Telenti, David B. Goldstein, Paul I. W. de Bakker, Jean-Francois Zagury, Jacques Fellay
Biology Faculty Articles

Risk Factors for Symptomatic Hyperlactatemia and Lactic Acidosis Among Combination Antiretroviral Therapy-Treated Adults in Botswana: Results from a Clinical Trial, C. William Wester, Svetlana K. Eden, Bryan E. Shepherd, Herman Bussmann, Vladimir Novitsky, David C. Samuels, Sher L. Hendrickson, Cheryl Winkler, Stephen J. O'Brien, Max Essex, Richard T. D'Aquila, Victor deGruttola, Richard G. Marlink
Biology Faculty Articles

Multicohort Genomewide Association Study Reveals a New Signal of Protection Against HIV-1 Acquisition, Sophie Limou, Olivier Delaneau, Danielle van Manen, Ping An, Efe Sezgin, Sigrid Le Clerc, Cedric Coulonges, Jennifer L. Troyer, Jan H. Veldink, Leonard H. van den Berg, Jean-Louis Spadoni, Lieng Taing, Taoufik Labib, Matthieu Montes, Jean-Francois Delfraissy, Francois Schachter, Stephen J. O'Brien, Susan Buchbinder, Mark Van Natta, Douglas A. Jabs, Philippe Froguel, Hanneke Schuitemaker, Cheryl Winkler, Jean-Francois Zagury
Biology Faculty Articles

Role of Exonic Variation in Chemokine Receptor Genes on AIDS: CCRL2 F167Y Association with Pneumocystis Pneumonia, Ping An, Rongling Li, Ji Ming Wang, Teizo Yoshimura, Munehisa Takahashi, Ram Samudralal, Stephen J. O'Brien, John Phair, James J. Goedert, Gregory D. Kirk, Jennifer L. Troyer, Efe Sezgin, Susan Buchbinder, Sharyne Donfield, George W. Nelson, Cheryl Winkler
Biology Faculty Articles

Genome-Wide Association Study Implicates PARD3B-Based AIDS Restriction, Jennifer L. Troyer, George W. Nelson, J. A. Lautenberger, Leslie Chinn, Carl McIntosh, Randall C. Johnson, Efe Sezgin, Bailey Kessing, Michael Malasky, Sher L. Hendrickson, Guan Li, J. U. Pontius, M. Tang, Ping An, Cheryl Winkler, Sophie Limou, Sigrid le Clerc, Olivier Delaneau, Jean-Francois Zagury, Hanneke Schuitemaker, Danielle van Manen, Jay H. Bream, Edward Gomperts, Susan Buchbinder, James J. Goedert, Gregory Kirk, Stephen J. O'Brien
Biology Faculty Articles

A Common HLA–DPA1 Variant is a Major Determinant of Hepatitis B Virus Clearance in Han Chinese, Ping An, Cheryl Winkler, Li Guan, Stephen J. O'Brien, Zheng Zeng, HBV Study Consortium
Biology Faculty Articles

Multistage Genomewide Association Study Identifies a Locus at 1q41 Associated with Rate of HIV-1 Disease Progression to Clinical AIDS, Joshua T. Herbeck, Geoffrey S. Gottlieb, Cheryl Winkler, George W. Nelson, Ping An, Brandon S. Maust, Kim G. Wong, Jennifer L. Troyer, James J. Goedert, Bailey Kessing, Roger Detels, Steven M. Wolinsky, Jeremy J. Martinson, Susan Buchbinder, Gregory D. Kirk, Lisa Jacobson, Joseph Margolick, Richard A. Kaslow, Stephen J. O'Brien, James I. Mullins
Biology Faculty Articles

A Population-Based Study to Investigate Host Genetic Factors Associated with Hepatitis B Infection and Pathogenesis in the Chinese Population, Zheng Zheng, Li Guan, Ping An, Shan Sun, Stephen J. O'Brien, Cheryl Winkler, HBV Study Consortium
Biology Faculty Articles

Regulatory Polymorphisms in the Cyclophilin A Gene, PPIA, Accelerate Progression to AIDS, Ping An, Li Hua Wang, Holli Hutcheson-Dilks, George Nelson, Sharyne Donfield, James J. Goedert, Charles Rinaldo, Susan Buchbinder, Gregory D. Kirk, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Polymorphisms of CUL5 are Associated with CD4+ T Cell Loss in HIV-1 Infected Individuals, Ping An, Priya Duggal, Li Hua Wang, Stephen J. O'Brien, Sharyne Donfield, James J. Goedert, John Phair, Susan Buchbinder, Gregory D. Kirk, Cheryl Winkler
Biology Faculty Articles

Effects of Human TRIM5α Polymorphisms on Antiretroviral Function and Susceptibility to Human Immunodeficiency Virus Infection, Hassan Javanbakht, Ping An, Bert Gold, Desiree C. Petersen, Colm O'Huigin, George W. Nelson, Roger Detels, Susan Buchbinder, Sharyne Donfield, Sergey Shulenin, Byeongwoon Song, Michel J. Perron, Matthew Stremlau, Joseph Sodroski, Michael Dean, Cheryl Winkler
Biology Faculty Articles

Genetic Variation in the CCL18-CCL3-CCL4 Chemokine Gene Cluster Influences HIV Type 1 Transmission and AIDS Disease Progression, William Modi, J. A. Lautenberger, Ping An, Kevin Scott, James J. Goedert, Gregory D. Kirk, Susan Buchbinder, John Phair, Sharyne Donfield, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Haplotype Analysis of the SDF-1 (CXCL12) Gene in a Longitudinal HIV-1/AIDS Cohort Study, William Modi, K. Scott, James J. Goedert, David Vlahov, Susan Buchbinder, Roger Detels, Sharyne Donfield, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Stromal Cell–Derived Factor–1 Genotype, Coreceptor Tropism, and HIV Type 1 Disease Progression, Eric S. Daar, Henry S. Lynn, Sharyne Donfield, Alice Lail, Stephen J. O'Brien, Wei Huang, Cheryl Winkler
Biology Faculty Articles

The Effect of RANTES Chemokine Genetic Variants on Early HIV-1 Plasma RNA Among African American Injection Drug Users, Priya Duggal, Cheryl Winkler, Ping An, Xiao-Fang Yu, Homayoon Farzadegan, Stephen J. O'Brien, T. H. Beaty, David Vlahov
Biology Faculty Articles

Dominant Effects of CCR2-CCR5 Haplotypes in HIV-1 Disease Progression, Cheryl Winkler, Houria Hendel, Mary Carrington, Michael W. Smith, George W. Nelson, Stephen J. O'Brien, John Phair, David Vlahov, Lisa Jacobson, Jay Rappaport, Alexandre Vasilescu, Sebastien Berlin-Maghit, Ping An, Wei Lu, Jean-Marie Andrieu, Francois Schachter, Amu Therwath, Jean-Francois Zagury
Biology Faculty Articles

Patterns of Ethnic Diversity Among the Genes That Influence AIDS, Cheryl Winkler, Ping An, Stephen J. O'Brien
Biology Faculty Articles

MCP-1-MCP-3–Eotaxin Gene Cluster Influences HIV-1 Transmission, William Modi, James J. Goedert, Steffanie A. Strathdee, Susan Buchbinder, Roger Detels, Sharyne Donfield, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

A Tumor Necrosis Factor-α-Inducible Promoter Variant of Interferon-γ Accelerates CD4+ T Cell Depletion in Human Immunodeficiency Virus-1-Infected Individuals, Ping An, David Vlahov, Joseph Margolick, John Phair, Thomas R. O'Brien, J. A. Lautenberger, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Genetic Influence of CXCR6 Chemokine Receptor Alleles on PCP-Mediated AIDS Progression Among African Americans, Priya Duggal, P. An, T. H. Beaty, Steffanie A. Strathdee, H. Farzadegan, R. D. Markham, L. Johnson, Stephen J. O'Brien, David Vlahov, Cheryl Winkler
Biology Faculty Articles

Haplotype Diversity in the Interleukin-4 Gene is Not Associated with HIV-1 transmission and AIDS Progression, William Modi, Thomas R. O'Brien, David Vlahov, Susan Buchbinder, Edward Gomperts, John Phair, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Validation of Genetic Case-Control Studies in AIDS and Application to the CX3CR1 Polymorphism, Houria Hendel, Cheryl Winkler, Ping An, Elisabeth Roemer-Binns, George Nelson, Philippe Haumont, Stephen J. O'Brien, Kamel Khalilli, Jean-Francois Zagury, Jay Rappaport, Jean-Francois Zagury
Biology Faculty Articles

Hepatitis C Virus Load is Associated with Human Immunodeficiency Virus Type 1 Disease Progression in Hemophiliacs, Eric S. Daar, Henry Lynn, Sharyne Donfield, Edward Gomperts, Stephen J. O'Brien, Margaret Hilgartner, Keith Hoots, David Chernoff, Steven Arkin, W.-Y. Wong, Cheryl Winkler, Hemophilia Growth and Development Study
Biology Faculty Articles

Genetic Heterogeneity and Molecular Epidemiology of GB Virus C/Hepatitis G Virus in China, Ping An, H. Luo, T. Lu, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Influence of CCR5 Promoter Haplotypes on AIDS Progression in African–Americans, Ping An, Maureen P. Martin, George W. Nelson, Mary Carrington, Michael W. Smith, Kui Gong, David Vlahov, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Polygenic and Multifactorial Disease Gene Association in Man: Lessons from AIDS, Stephen J. O'Brien, George W. Nelson, Cheryl Winkler, Michael W. Smith
Biology Faculty Articles

Effects of Plasma HIV RNA, CD4+ T Lymphocytes, and the Chemokine Receptors CCR5 and CCR2b on HIV Disease Progression in Hemophiliacs, Eric S. Daar, Sharyne Donfield, Edward Gomperts, Margaret Hilgartner, Keith Hoots, David Chernoff, Cheryl Winkler, Stephen J. O'Brien, Hemophilia Growth and Development Study
Biology Faculty Articles

New Class I and II HLA Alleles Strongly Associated with Opposite Patterns of Progression to AIDS, Houria Hendel, Sophie Caillat-Zucman, Helene Lebuanec, Mary Carrington, Stephen J. O'Brien, Jean-Marie Andrieu, Francois Schachter, Daniel Zagury, Jay Rappaport, Cheryl Winkler, George W. Nelson, Jean-Francois Zagury
Biology Faculty Articles

Distinctive Effects of CCR5, CCR2, and SDF1 Genetic Polymorphisms in AIDS Progression, Houria Hendel, N. Henon, Helene Lebuanec, Abderrahim Lachgar, H. Poncelet, Sophie Caillat-Zucman, Cheryl Winkler, Michael W. Smith, L. Kenefic, Stephen J. O'Brien, W. Lu, Jean-Marie Andrieu, Daniel Zagury, Francois Schachter, Jay Rappaport, Jean-Francois Zagury
Biology Faculty Articles

Genetic Acceleration of AIDS Progression by a Promoter Variant of CCR5, Maureen P. Martin, Michael Dean, Michael W. Smith, Cheryl Winkler, Bernard Gerrard, Nelson L. Michael, Benhur Lee, Robert W. Doms, Joseph Margolick, Susan Buchbinder, James J. Goedert, Thomas R. O'Brien, Margaret Hilgartner, David Vlahov, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles

Progression to AIDS, Sharyne Donfield, Henry S. Lynn, Margaret Hilgartner, Michael W. Smith, Michael Dean, Mary Carrington, Cheryl Winkler, Stephen J. O'Brien
Biology Faculty Articles

Evolutionary Analysis of the 5'-Terminal Region of Hepatitis G Virus Isolated From Different Regions in China, Ping An, Li Wei, Xueyun Wu, Naoya Yuhki, Stephen J. O'Brien, Cheryl Winkler
Biology Faculty Articles

Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression, Michael W. Smith, Michael Dean, Mary Carrington, Cheryl Winkler, Gavin A. Huttley, Deborah A. Lomb, James J. Goedert, Thomas R. O'Brien, Lisa Jacobson, Richard A. Kaslow, Susan Buchbinder, Eric Vittinghoff, David Vlahov, Keith Hoots, Margaret Hilgartner, Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study, Stephen J. O'Brien
Biology Faculty Articles

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene, Michael Dean, Mary Carrington, Cheryl Winkler, Gavin A. Huttley, Michael W. Smith, Rando Allikmets, James J. Goedert, Susan Buchbinder, Eric Vittinghoff, Edward Gomperts, Sharyne Donfield, David Vlahov, Richard A. Kaslow, A. J. Saah, Charles Rinaldo, Roger Detels, Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, Stephen J. O'Brien
Biology Faculty Articles