Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2, Skye R. Doering, Katie T. Freeman, Sathya M. Schnell, Erica M. Haslach, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh Santos, Marc A. Giulianotti, Clemencia Pinilla, Jon R. Appel, Robert Charles Speth, Richard A. Houghten, Carrie Haskell-Luevano
Robert Speth

Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist, Mark D. Ericson, Skye R. Doering, Courtney M. Larson, Katie T. Freeman, Travis M. LaVoi, Haley M. Donow, Radleigh G. Santos, Rachel H. Cho, Zoe M. Koerperich, Marc A. Giulianotti, Clemencia Pinilla, Richard A. Houghten, Carrie Haskell-Luevano
Mathematics Faculty Articles

Inhibition of Aminoglycoside 6’-N-Acetyltransferase Type Ib [Aac(6′)-Ib]: Structure-Activity Relationship of Substituted Pyrrolidine Pentamine Derivatives as Inhibitors, Kenneth Rocha, Jesus Magallon, Craig Reeves, Kimberly Phan, Peter Vu, Crista L. Oakley-Havens, Stella Kwan, Maria S. Ramirez, Travis LaVoi, Haley Donow, Prem Chapagain, Radleigh Santos, Clemencia Pinilla, Marc A. Giulianotti, Marcelo E. Tolmasky
Mathematics Faculty Articles

Scaffold Ranking and Positional Scanning Identify Novel Neurite Outgrowth Promoters with Nanomolar Potency, Hassan Al-Ali, Ginamarie Debevec, Radleigh Santos, Richard A. Houghten, Jennifer C. Davis, Adel Nefzi, Vance P. Lemmon, John L. Bixby, Marc A. Giulianotti
Radleigh Santos

Scaffold Ranking and Positional Scanning Identify Novel Neurite Outgrowth Promoters with Nanomolar Potency, Hassan Al-Ali, Ginamarie Debevec, Radleigh Santos, Richard A. Houghten, Jennifer C. Davis, Adel Nefzi, Vance P. Lemmon, John L. Bixby, Marc A. Giulianotti
Mathematics Faculty Articles

Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2, Skye R. Doering, Katie T. Freeman, Sathya M. Schnell, Erica M. Haslach, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh Santos, Marc A. Giulianotti, Clemencia Pinilla, Jon R. Appel, Robert Charles Speth, Richard A. Houghten, Carrie Haskell-Luevano
Mathematics Faculty Articles

Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library, Laura D. Hamel, Brian J. Lenhart, David A. Mitchell, Radleigh Santos, Marc A. Giulianotti, Robert J. Deschenes
Mathematics Faculty Articles

Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734 821 Pyrrolidine Bis-piperazines, Richard A. Houghten, Michelle L. Ganno, Jay P. McLaughlin, Colette T. Dooley, Shainnel O. Eans Torrey Pines Institute for Molecular Studies, Radleigh Santos, Travis LaVoi, Adel Nefzi, Greg Welmaker, Marc A. Giulianotti, Lawrence Toll
Mathematics Faculty Articles

Novel T cell driven approach leads to the identification of immunoprevalent antigens, Valeria A. Judkowski, Radleigh G. Santos, Alcinette Bunying, Marc A. Giulianotti, Jon R. Appel, Clemencia Pinilla
Mathematics Faculty Articles