Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2, Skye R. Doering, Katie T. Freeman, Sathya M. Schnell, Erica M. Haslach, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh Santos, Marc A. Giulianotti, Clemencia Pinilla, Jon R. Appel, Robert Charles Speth, Richard A. Houghten, Carrie Haskell-Luevano
Robert Speth

Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist, Mark D. Ericson, Skye R. Doering, Courtney M. Larson, Katie T. Freeman, Travis M. LaVoi, Haley M. Donow, Radleigh G. Santos, Rachel H. Cho, Zoe M. Koerperich, Marc A. Giulianotti, Clemencia Pinilla, Richard A. Houghten, Carrie Haskell-Luevano
Mathematics Faculty Articles

Discovery of Selective Nanomolar Potent Melanocortin-3 Receptor Ligands, Skye R. Doering, Phaedra Geer, Radleigh Santos, Marc Giulianotti, Clemencia Pinilla, Jon R. Appel, Richard A. Houghten, Carrie Haskell-Luevano
Radleigh Santos

Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist Versus a μM MC4R Partial Agonist, Katlyn A. Fleming, Katie T. Freeman, Mike D. Powers, Radleigh Santos, Ginamarie Debevac, Marc Giulianotti, Richard A. Houghten, Skye R. Doering, Clemencia Pinilla, Carrie Haskell-Luevano
Radleigh Santos

Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist Versus a μM MC4R Partial Agonist, Katlyn A. Fleming, Katie T. Freeman, Mike D. Powers, Radleigh Santos, Ginamarie Debevac, Marc Giulianotti, Richard A. Houghten, Skye R. Doering, Clemencia Pinilla, Carrie Haskell-Luevano
Mathematics Faculty Articles

Discovery of Selective Nanomolar Potent Melanocortin-3 Receptor Ligands, Skye R. Doering, Phaedra Geer, Radleigh Santos, Marc Giulianotti, Clemencia Pinilla, Jon R. Appel, Richard A. Houghten, Carrie Haskell-Luevano
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Melanocortin Ligands and Methods of Use Thereof, Carrie Haskell-Luevano, Skye R. Doering, Jon R. Appel, Marc Giulianotti, Richard A. Houghten, Clemencia Pinilla, Radleigh Santos
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2, Skye R. Doering, Katie T. Freeman, Sathya M. Schnell, Erica M. Haslach, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh Santos, Marc A. Giulianotti, Clemencia Pinilla, Jon R. Appel, Robert Charles Speth, Richard A. Houghten, Carrie Haskell-Luevano
Mathematics Faculty Articles

Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin-4 Polymorphic Receptors (hMC4Rs), Erica M. Haslach, Huisuo Huang, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh Santos, Marc Giulianotti, Clemencia Pinilla, Jon R. Appel, Skye R. Doering, Michael A. Walters, Richard A. Houghten, Carrie Haskell-Luevano
Mathematics Faculty Articles