Biscyclic guanidine compound compositions, methods of use and treatment thereof, Lindsey Shaw, Renee Fleeman, Richard A. Houghten, Marc Giulianotti, Radleigh Santos, Adel Nefzi
Mathematics Faculty Proceedings, Presentations, Speeches, Lectures

Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities, Miao Hu, Marc Giulianotti, Jay P. McLaughlin, Jiaan Shao, Ginamarie Debevec, Laura E. Maida, Phaedra Geer, Margaret Cazares, Jaime Misler, Ling Li, Colette T. Dooley, Michelle L. Ganno, Shainnel O. Eans Torrey Pines Institute for Molecular Studies, Elisa Mizrachi, Radleigh Santos, Austin B. Yongye, Richard A. Houghten, Yongping Yu
Mathematics Faculty Articles

Combinatorial Libraries As a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens, Renee Fleeman, Travis LaVoi, Radleigh Santos, Angela Morales, Adel Nefzi, Greg Welmaker, Jose L. Medina-Franco, Marc Giulianotti, Richard A. Houghten, Lindsey N. Shaw
Mathematics Faculty Articles

Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin-4 Polymorphic Receptors (hMC4Rs), Erica M. Haslach, Huisuo Huang, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh Santos, Marc Giulianotti, Clemencia Pinilla, Jon R. Appel, Skye R. Doering, Michael A. Walters, Richard A. Houghten, Carrie Haskell-Luevano
Mathematics Faculty Articles

Selective Agonists and Antagonists of Formylpeptide Receptors: Duplex Flow Cytometry and Mixture-based Positional Scanning Libraries, Clemencia Pinilla, Bruce S. Edwards, Jon R. Appel, Tina Yates-Gibbins, Marc Giulianotti, Jose L. Medina-Franco, Susan M. Young, Radleigh Santos, Larry A. Sklar, Richard A. Houghten
Mathematics Faculty Articles

Conditional Probabilistic Analysis for Prediction of the Activity Landscape and Relative Compound Activities, Radleigh Santos, Marc Giulianotti, Richard A. Houghten, Jose L. Medina-Franco
Mathematics Faculty Articles

Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease, Michael T. Falta, Clemencia Pinilla, Douglas G. Mack, Alex N. Tinega, Francis Crawford, Marc Giulianotti, Radleigh Santos, Gina M. Clayton, Yuxiao Wang, Xuewu Zhang, Lisa A. Maier, Philippa Marrack, John W. Kappler, Andrew P. Fontenot
Mathematics Faculty Articles

Rapid Scanning Structure–Activity Relationships in Combinatorial Data Sets: Identification of Activity Switches, Jose L. Medina-Franco, Bruce S. Edwards, Clemencia Pinilla, Jon R. Appel, Marc Giulianotti, Radleigh Santos, Austin B. Yongye, Larry A. Sklar, Richard A. Houghten
Mathematics Faculty Articles

The Mathematics of a Successful Deconvolution: A Quantitative Assessment of Mixture-Based Combinatorial Libraries Screened Against Two Formylpeptide Receptors, Radleigh Santos, Jon R. Appel, Marc Giulianotti, Bruce S. Edwards, Larry A. Sklar, Richard A. Houghten, Clemencia Pinilla
Mathematics Faculty Articles

A Novel Method for the Determination of Isokinetic Ratios and Its Application in the Synthesis of Two New Positional Scanning Libraries, Marc Giulianotti, Ginamarie Debevac, Radleigh Santos, Laura E. Maida, Wenteng Chen, Lili Ou, Yongping Yu, Colette T. Dooley, Richard A. Houghten
Mathematics Faculty Articles

GM-CSF Production Allows the Identification of Immunoprevalent Antigens Recognized by Human CD4+ T Cells Following Smallpox Vaccination, Valeria A. Judkowski, Alcinette Bunying, Feng Ge, Jon R. Appel, Kingyee Law, Atima Sharma, Claudia Raja-Gabaglia, Patricia Norori, Radleigh Santos, Marc Giulianotti, Mark K. Slifka, Daniel C. Douek, Barney S. Graham, Clemencia Pinilla
Mathematics Faculty Articles

Characterization of a comprehensive flavor database, Karina Martinez-Mayorga, Terry L. Peppard, Austin B. Yongye, Radleigh Santos, Marc Giulianotti, Jose L. Medina-Franco
Mathematics Faculty Articles

Use and Implications of the Harmonic Mean Model on Mixtures for Basic Research and Drug Discovery, Radleigh Santos, Marc Giulianotti, Colette T. Dooley, Clemencia Pinilla, Jon R. Appel, Richard A. Houghten
Mathematics Faculty Articles

Towards a systematic characterization of the antiprotozoal activity landscape of benzimidazole derivatives, Jaime Perez-Villanueva, Radleigh Santos, Alicia Hernandez-Campos, Marc Giulianotti, Rafael Castillo, Jose L. Medina-Franco
Mathematics Faculty Articles

Structure–activity relationships of benzimidazole derivatives as antiparasitic agents: Dual activity-difference (DAD) maps, Jaime Perez-Villanueva, Radleigh Santos, Alicia Hernandez-Campos, Marc Giulianotti, Rafael Castillo, Jose L. Medina-Franco
Mathematics Faculty Articles