The Feasibility of Modified Directly Observed Therapy for HIV-Seropositive African American Substance Users

Author(s)

Mindy M. Ma, Nova Southeastern UniversityFollow
Billy R. Brown, G.V. (Sonny) Montgomery Medical Center
Melissa Coleman, Central Mississippi Medical Center Inspiration
Jeffrey L. Kibler, Nova Southeastern UniversityFollow
Helen Loewenthal, Miriam Hospital and Brown University School of Medicine
Jennifer A. Mitty, Miriam Hospital and Brown University School of Medicine

Document Type

Article

Publication Date

2-9-2008

Publication Title

AIDS Patient Care and STDs

Volume

22

Issue/Number

2

First Page

139

ISSN

1087-2914

Last Page

146

Abstract/Excerpt

Recently, modified directly observed therapy (MDOT) has emerged as a promising intervention to address nonadherence for hard-to-reach populations infected with HIV. To date, there are no existing data on MDOT focusing exclusively on African Americans. The present study sought to determine the feasibility of MDOT among 31 HIV-seropositive African American substance users in the South. An outreach worker observed the participants’ medication intake 5 days per week (once per day) for a period of 3 months (intensive phase). This phase was followed by a transition phase of 3 months during which the frequency of MDOT was gradually tapered from 5 days to once weekly. Assessments to gather demographic information, HIV risk behaviors, substance use, depression, and medication adherence were conducted at baseline, 3 months, and 6 months. Results indicated that more participants adhered to their medication regimen and had viral loads of less than 400 copies per milliliter at 3 and 6 months compared to baseline. Participants reported significantly less depressive symptoms at the 6-month assessment compared to baseline and 3 months. With regard to acceptability, 95% of participants indicated they liked having the outreach visits, 100% reported MDOT helped them take their medications, and only 5% felt MDOT was a violation of privacy. These results suggest MDOT is feasible among African American substance users in the South and a larger controlled study of MDOT with this population is warranted.

DOI

10.1089/apc.2007.0063

Comments

This is a copy of an article published in the AIDS Patient Care and STDs © 2008, copyright Mary Ann Liebert, Inc.; AIDS Patient Care and STDs is available online at: http://www.liebertpub.com/

NSUWorks Citation

Ma, M. M., Brown, B. R., Coleman, M., Kibler, J. L., Loewenthal, H., Mitty, J. A. (2008). The Feasibility of Modified Directly Observed Therapy for HIV-Seropositive African American Substance Users. AIDS Patient Care and STDs, 22(2), 139-146.
Available at: https://nsuworks.nova.edu/cps_facarticles/3