Changes in prevalence of prescription opioid abuse after introduction of an abuse-deterrent opioid formulation
The reformulation of oxycodone hydrochloride controlled-release (CR) tablets in August 2010 created a natural experiment at a national scale, providing an opportunity to evaluate patterns of abuse of prescription opioids and other drugs before and after introduction of this abuse-deterrent formulation (ADF).
Cassidy, T. A.,
Black, R. A.,
Wieman, M. S.,
Butler, S. F.
(2014). Changes in prevalence of prescription opioid abuse after introduction of an abuse-deterrent opioid formulation. Pain Medicine, 15(3), 440-451.
Available at: https://nsuworks.nova.edu/cps_facarticles/1527