Biology Faculty Proceedings, Presentations, Speeches, Lectures
Event Name/Location
23rd International Colloquium on Animal Cytogenetics and Genomics, June 9-12, Saint Petersburg, Russia
Presntation Date
2018
Document Type
Conference Proceeding
ORCID ID
0000-0001-7353-8301
ResearcherID
N-1726-2015
Proceeding Title
Comparative Cytogenetics v.12(3)
ISSN
1993-0771
Description
The mammalian X chromosome is characterized by high level of conservation. On the contrary the Cetartiodactyl X chromosome displays variation in morphology and G-banding pattern. It is hypothesized that X chromosome has undergone multiple rearrangements during Cetartiodactyla speciation. To investigate the evolution of this sex chromosome we have selected 26 BAC clones from cattle CHORI-240 library evenly distributed along the cattle X chromosome. High-resolution maps were obtained by fluorescence in situ hybridisation in a representative range of cetartiodactyl species from different families: pig (Suidae), gray whale (Eschrichtiidae), pilot whale (Delphinidae), hippopotamus (Hippopotamidae), Java mouse deer (Tragulidae), pronghorn (Antilocapridae), Siberian musk deer (Moschidae), giraffe (Giraffidae). To trace the X chromosome evolution during fast radiation in speciose families, we mapped more than one species in Cervidae (moose, Siberian roe deer, fallow deer and Pere David’s deer) and Bovidae (musk ox, goat, sheep, sable antelope, nilgau, gaur, saola, and cattle). We have identified three major conserved synteny blocks and based on this data reconstructed the structure of putative ancestral cetartiodactyl X chromosome. We demonstrate that intrachromosomal rearrangements such as inversions and centromere reposition are main drivers of cetartiodactyl’s chromosome X evolution.
DOI
10.3897/CompCytogen.v12i3.27748
First Page
307
Last Page
308
Additional Comments
Russian Science Foundation grant #: 16-14-10009
NSUWorks Citation
Proskuryakova, Anastasiya A.; Kulemzina, Anastasia I.; Perelman, Polina L.; Makunin, Alexey I.; Lemskaya, Natalya A.; Beklemisheva, Violetta R.; Larkin, Denis M.; Farre, Marta; Kukekova, Anna V.; Ryder, Oliver A.; O'Brien, Stephen James; and Graphodatsky, Alexander S., "X Chromosome Evolution in Cetartiodactyla" (2018). Biology Faculty Proceedings, Presentations, Speeches, Lectures. 322.
https://nsuworks.nova.edu/cnso_bio_facpres/322
Comments
Copyright S. Galkina, M. Vishnevskaya. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.