Biology Faculty Proceedings, Presentations, Speeches, Lectures

Event Name/Location

23rd International Colloquium on Animal Cytogenetics and Genomics, June 9-12, Saint Petersburg, Russia

Document Type

Conference Proceeding

Publication Date

2018

Abstract

The mammalian X chromosome is characterized by high level of conservation. On the contrary the Cetartiodactyl X chromosome displays variation in morphology and G-banding pattern. It is hypothesized that X chromosome has undergone multiple rearrangements during Cetartiodactyla speciation. To investigate the evolution of this sex chromosome we have selected 26 BAC clones from cattle CHORI-240 library evenly distributed along the cattle X chromosome. High-resolution maps were obtained by fluorescence in situ hybridisation in a representative range of cetartiodactyl species from different families: pig (Suidae), gray whale (Eschrichtiidae), pilot whale (Delphinidae), hippopotamus (Hippopotamidae), Java mouse deer (Tragulidae), pronghorn (Antilocapridae), Siberian musk deer (Moschidae), giraffe (Giraffidae). To trace the X chromosome evolution during fast radiation in speciose families, we mapped more than one species in Cervidae (moose, Siberian roe deer, fallow deer and Pere David’s deer) and Bovidae (musk ox, goat, sheep, sable antelope, nilgau, gaur, saola, and cattle). We have identified three major conserved synteny blocks and based on this data reconstructed the structure of putative ancestral cetartiodactyl X chromosome. We demonstrate that intrachromosomal rearrangements such as inversions and centromere reposition are main drivers of cetartiodactyl’s chromosome X evolution.

Comments

Copyright S. Galkina, M. Vishnevskaya. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Additional Comments

Russian Science Foundation grant #: 16-14-10009

Conference Proceeding Title

Comparative Cytogenetics v.12(3)

ISSN

1993-0771

DOI

10.3897/CompCytogen.v12i3.27748

First Page

307

Last Page

308

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015

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