Biology Faculty Articles
Cloning, Characterization, Expression, and Chromosomal Localization of a Human Ferritin Heavy-Chain Gene
Proceedings of the National Academy of Sciences of the United States of America
A genomic phage clone containing a full-length copy of a functional human gene for ferritin heavy chain has been isolated. The gene consists of four exons spanning approximately 3 kilobases and has been localized to chromosome 11. The functionality of the gene was demonstrated by the fact that both transient transfectants and stable transformants of murine fibroblasts actively transcribe human ferritin heavy-chain mRNA.
Hentze, Matthias W.; Stephen Keim; Panos Papadopoulos; Stephen J. O'Brien; William Modi; Jim Drysdale; William J. Leonard; Joe B. Harford; and Richard D. Klausner. 1986. "Cloning, Characterization, Expression, and Chromosomal Localization of a Human Ferritin Heavy-Chain Gene." Proceedings of the National Academy of Sciences of the United States of America 83, (19): 7226-7230. https://nsuworks.nova.edu/cnso_bio_facarticles/241
National Institute of Health Grant #AM17775