Biology Faculty Articles

Document Type

Article

Publication Date

9-1983

Publication Title

Journal of Virology

ISSN

0022-538X

Volume

47

Issue/No.

3

First Page

649

Last Page

651

Abstract

The two murine retroviral restriction genes, Fv-4 and Akvr-1, are very similar in their effects, distributions, ranges of action, and phenotypes. Akvr-1 has been shown to segregate independently in backcrosses with a variety of retroviral restriction loci, including Fv-1, Fv-2, Ril-1, and Ril-2. An allelism test cross of FRG (Fv-4R) x LCRR (Akvr-1R) hybrids mated to AKR mice failed to produce any viremic offspring. These results suggested that Akvr-1R and Fv-4R are alleles of a single locus, Fv-4, on mouse chromosome 12.

Comments

©1983, American Society for Microbiology

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015

Peer Reviewed

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