Biology Faculty Articles
Genetic Mapping in Mammals: Chromosome Map of Domestic Cat
A genetic map of 31 biochemical loci located on 17 feline syntenic (linkage) groups has been derived by somatic cell genetic analysis of cat-rodent hybrids. Most of these syntenic groups have been assigned to one of the 19 feline chromosomes. Comparative linkage analysis of the feline biochemical loci and homologous human loci revealed considerable conservation of linkage associations between the primates and the Felidae (order Carnivora). Many of these same linkage groups have not been conserved in the murine genome. The genetic and evolutionary implications of comparative mapping analysis among mammalian species are discussed.
O'Brien, Stephen J. and William G. Nash. 1982. "Genetic Mapping in Mammals: Chromosome Map of Domestic Cat." Science 216, (4543): 257-265. doi:10.1126/science.7063884.
©1982 American Association for the Advancement of Science