College of Osteopathic Medicine Faculty Articles

Title

Clinical characteristics of community-dwelling black Alzheimer's disease patients.

ISBN or ISSN

0027-9684

Publication Title

Journal of the National Medical Association

Volume

92

Issue

9

Publication Date / Copyright Date

9-1-2000

First Page

424

Last Page

429

Publisher

Slack for the National Medical Association

Abstract

There is a relative dearth of studies examining the cognitive and neuropsychiatric features of black Alzheimer's disease (AD) patients in the United States. Therefore, this cross-sectional investigation reported on the prevalence and clinical correlates of depression and psychosis in a community-dwelling black AD sample. The study participants comprised 55 English-speaking black patients evaluated consecutively at a university-affiliated memory disorders clinic. All patients were evaluated utilizing standardized procedures and diagnosed with possible or probable AD according to the criteria established by the National Institute of Neurological and Communicative Diseases and Stroke-Alzheimer's Disease and Related Disorders Association. The presence of neuropsychiatric symptoms, including major depression and psychosis (delusions or hallucinations) was established via a semistructured psychiatric interview with the patient and primary care giver. The level of global cognitive impairment was rated with the Mini-Mental State Examination. The results showed that major depression and psychosis were observed in 20% and 58% of the sample, respectively. Mood disturbance was linked with low education, whereas psychosis was associated with greater cognitive dysfunction. This study provides important insight into the clinical characteristics of community-dwelling black AD patients. It is clear that continued research in the area of ethnicity and dementia is warranted to better understand the clinical needs of blacks and other minority populations in the United States that are afflicted with AD.

Disciplines

Medical Specialties | Medicine and Health Sciences | Osteopathic Medicine and Osteopathy

Keywords

African Continental Ancestry Group, Aged, Alzheimer Disease, Cross-Sectional Studies, Depressive Disorder, Female, Florida, Humans, Logistic Models, Male, Prevalence, Psychotic Disorders, Risk Factors