College of Psychology: Faculty Articles

Title

Issues in designing and implementing a Spanish-language multisite clinical trial.

Document Type

Article

Publication Date

5-2007

Keywords

Communication Barriers, Culture, Emigration and Immigration, Ethnic Groups, Multicenter Studies as Topic, Multilingualism, Patient Dropouts, Patient Selection, Randomized Controlled Trials as Topic, Research Design, Research Personnel, Substance-Related Disorders, United States

Publication Title

American Journal on Addictions

ISSN

1055-0496

Volume

16

Issue/No.

3

Abstract

To address at least in part health disparities in Hispanic populations, the NIDA Clinical Trials Network implemented the first multi-site randomized clinical trial of substance abuse treatment conducted entirely in Spanish. This trial was intended to evaluate the effectiveness of Motivational Enhancement Therapy in a diverse population of Hispanics. In the conduct of this trial, several barriers to the successful implementation of a Spanish-language multi-site trial had to be addressed, including the appropriate translation of assessment instruments, shortage of appropriately trained Spanish-speaking clinical staff, and barriers to recruitment and retention of this population. To encourage similar research, strategies are described that were developed by the study team to meet these challenges.

DOI

10.1080/10550490701375707