Issues in designing and implementing a Spanish-language multisite clinical trial.
Communication Barriers, Culture, Emigration and Immigration, Ethnic Groups, Multicenter Studies as Topic, Multilingualism, Patient Dropouts, Patient Selection, Randomized Controlled Trials as Topic, Research Design, Research Personnel, Substance-Related Disorders, United States
American Journal on Addictions
To address at least in part health disparities in Hispanic populations, the NIDA Clinical Trials Network implemented the first multi-site randomized clinical trial of substance abuse treatment conducted entirely in Spanish. This trial was intended to evaluate the effectiveness of Motivational Enhancement Therapy in a diverse population of Hispanics. In the conduct of this trial, several barriers to the successful implementation of a Spanish-language multi-site trial had to be addressed, including the appropriate translation of assessment instruments, shortage of appropriately trained Spanish-speaking clinical staff, and barriers to recruitment and retention of this population. To encourage similar research, strategies are described that were developed by the study team to meet these challenges.
Ball, S. A.,
Carroll, K. M.
(2007). Issues in designing and implementing a Spanish-language multisite clinical trial.. American Journal on Addictions, 16(3), 206-215.
Available at: http://nsuworks.nova.edu/cps_facarticles/157